A group of proteins called 4E-BPs, involved in memory formation, is the key to unlocking the antidepressant effect of ketamine in the brain, according to researchers from three Canadian universities. The discovery could lead to better and safer treatments for certain patients suffering from major depression.

Classified as: ketamine, depression, antidepressant, brain, Nahum Sonenberg, Gabriella Gobbi
Published on: 16 Dec 2020

McGill Newsroom

Antidepressant use in North America has increased over the last 2 decades. A suspected reason for this trend is that primary care physicians are increasingly prescribing antidepressants for nondepressive indications, including unapproved (off-label) indications that have not been evaluated by regulatory agencies.

Classified as: depression, pain, health and lifestyle, antidepressant, Jenna Wong, manoamine oxidase inhibitors, insomnia, panic disorders
Published on: 24 May 2016
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