Gary Armstrong will use fish models to understand nervous system signaling

A researcher from the Montreal Neurological Institute and Hospital (The Neuro) is one of eight scientists to receive a grant this year from the ALS Society of Canada.

Gary Armstrong, who joined The Neuro in 2017, is furthering our understanding of synaptic defects arising both at peripheral neuromuscular junctions and central spinal cord synapses in Amyotrophic Lateral Sclerosis (ALS) using zebrafish models. The award is valued at $125,000.

Classified as: MNI, medicine research, ALS research, ALS Society of Canada, Gary Armstrong
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Published on: 16 Nov 2018

Carriers at higher risk of developing neurodegenerative disease

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital (The Neuro) has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson’s disease (PD), dementia with Lewy-Bodies (DLB) and multiple system atrophy (MSA).

Classified as: MNI, genetics, Parkinson's disease, Healthy Brains for Healthy Lives, multiple system atrophy, Lewy-Bodies, PD, Ziv Gan-Or
Published on: 1 Oct 2018

Technique can be used to better categorize patients with neurological disease, according to their therapeutic needs

Personalized medicine – delivering therapies specially tailored to a patient’s unique physiology – has been a goal of researchers and doctors for a long time. New research provides a way of delivering personalized treatments to patients with neurological disease.

Classified as: Ludmer Centre, neuroinformatics, The Neuro, Neuro, MNI, Yasser Iturria Medina, Dr Yasser Iturria-Medina, Yasser Iturria-Medina
Published on: 10 Jul 2018

Finding is key for future treatment and earlier diagnosis 

Scientists at the Montreal Neurological Institute and Hospital (The Neuro) of McGill University have used a unique approach to track brain degeneration in Alzheimer’s disease, uncovering a pathway through which degeneration spreads from one region to another.

Classified as: Alzheimer's, MNI, Nathan Spreng
Published on: 4 Jul 2018

Montreal — In a study published in Stem Cell Reports, a McGill team of scientists led by Dr. Carl Ernst, researcher at the Douglas Hospital Research Centre, revealed a molecular mechanism that may play a role in the development of autism.

Classified as: MNI, Douglas Research Institute, autism
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Published on: 26 Jun 2018

CENTECH, a Montreal-based technology incubator, announced earlier that it has selected a company founded by Dr. Etienne de Villers-Sidani for its Propulsion Program, which helps the most innovative start-ups move from the initial development phase to commercializing their products and services on the international market. Dr. de Villers-Sidani is a researcher and neurologist at Montreal Neurological Institute and Hospital (The Neuro) and member of the Center for Research on Brain, Language and Music (CRBLM).

Classified as: MNI, neuroscience, The Neuro, Étienne de Villers-Sidani, Etienne De Villers-Sidan
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Published on: 16 May 2018

A study by a group of researchers including those from The Montreal Neurological Institute and Hospital of McGill University has tested the theory that brain degeneration in Parkinson’s disease (PD) originates in subcortical regions and spreads along neural networks to the cerebral cortex. By analyzing data on PD patients and healthy controls collected over one year, the researchers found that brain regions closely connected to subcortical regions showed the most degeneration over the one-year period in PD patients, and that this happens earlier than previously thought.

Classified as: Parkinson's, Montreal Neurological Institute and Hospital, MNI
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Published on: 11 Jan 2018

NeuroSGC created to increase volume and quality of cell assays for drug discovery

A new partnership between the Structural Genomics Consortium (SGC) and the Montreal Neurological Institute and Hospital (The Neuro) will use a unique open science framework to help scientists discover new targets for drug development for neurological diseases.

The partnership, called NeuroSGC, will initially focus on Parkinson’s disease and amyotrophic lateral sclerosis (ALS), two of the most common neurodegenerative diseases.

Classified as: open science, MNI, Guy Rouleau
Published on: 6 Dec 2017

By Shawn Hayward

Whether it is dancing or just tapping one foot to the beat, we all experience how auditory signals like music can induce movement. Now new research suggests that motor signals in the brain actually sharpen sound perception, and this effect is increased when we move in rhythm with the sound.

Classified as: auditory response, Sound, Motor signals, Sound perception, MNI, Montreal Neurological Institute & Hospital, science, External, staff, students, faculty
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Published on: 6 Oct 2017

Lawyers representing both sides in concussion lawsuits against sports leagues may eventually have a new tool at their disposal: a diagnostic signature that uses artificial intelligence to detect brain trauma years after it has occurred. 

Classified as: Montreal Neurological Institute and Hospital (The Neuro), MNI, Research News, Athletics, concussion in athletics, External, faculty, MRI, staff, students, Sports, concussions
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Published on: 12 Jul 2017

Much work to be done to improve diagnosis and treatment

When NHL star player Sidney Crosby suffered a concussion during a game in May – the fourth concussion of his career – the news made nationwide headlines. A few years earlier, a concussion had kept the Pittsburgh Penguins star off the ice for ten months.

Concussions can have serious consequences, even in cases where the victim shows few symptoms immediately. Victims often shrug off a mild blow to the head, unaware that brain damage has occurred.

Classified as: Sports, concussions, football, mental health, medicine research, MNI, Neuro, Neurology, alain ptito
Published on: 7 Jun 2017

Deep learning transforming neuroscience research

In an article published in Nature on Feb. 15, 2017, researchers, including principal investigators from the Montreal Neurological Institute’s McConnell Brain Imaging Centre (BIC), used magnetic resonance imaging (MRI) to predict the development of autism in babies.

Classified as: MNI, autism, Neuro, Sylvain Baillet, BIC, neuroimaging, brain imaging centre, deep learning
Published on: 20 Mar 2017

Discovery could be key to treating brain and spinal cord injury

A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.

Classified as: Neuro, MNI, stroke, Neurology, spinal cord injury, axon repair, 14-3-3, Fusicoccin-A, Alyson Fournier
Published on: 8 Mar 2017

Dec. 1 is World AIDS Day, a time to raise awareness about a disease that has afflicted 70 million people worldwide, 35 million of whom have died as a result.

When most people think of AIDS, they generally do not think of a neurological disease, yet HIV infection can have an important impact on brain function. Untreated, HIV can cause severe dementia.

Classified as: MNI, Lesley Fellows, World AIDS Day, Department of Neurology & Neurosurgery
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Published on: 30 Nov 2016

McGill Newsroom

Chemicals found to improve low-light vision of tadpoles by sensitizing retinal cells

A multidisciplinary team including researchers from the Montreal Neurological Institute has improved our understanding of how cannabinoids, the active agent in marijuana, affect vision in vertebrates.

Classified as: Montreal Neurological Institute, MNI, tadpoles, vision, marijuana, health and lifestyle, cannabis, vertebrates, RGC, CB1R
Published on: 25 Aug 2016

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