A study by a group of researchers including those from The Montreal Neurological Institute and Hospital of McGill University has tested the theory that brain degeneration in Parkinson’s disease (PD) originates in subcortical regions and spreads along neural networks to the cerebral cortex. By analyzing data on PD patients and healthy controls collected over one year, the researchers found that brain regions closely connected to subcortical regions showed the most degeneration over the one-year period in PD patients, and that this happens earlier than previously thought.

Classified as: Parkinson's, Montreal Neurological Institute and Hospital, MNI
Published on: 11 Jan 2018

NeuroSGC created to increase volume and quality of cell assays for drug discovery

A new partnership between the Structural Genomics Consortium (SGC) and the Montreal Neurological Institute and Hospital (The Neuro) will use a unique open science framework to help scientists discover new targets for drug development for neurological diseases.

The partnership, called NeuroSGC, will initially focus on Parkinson’s disease and amyotrophic lateral sclerosis (ALS), two of the most common neurodegenerative diseases.

Classified as: open science, MNI
Published on: 6 Dec 2017

By Shawn Hayward

Whether it is dancing or just tapping one foot to the beat, we all experience how auditory signals like music can induce movement. Now new research suggests that motor signals in the brain actually sharpen sound perception, and this effect is increased when we move in rhythm with the sound.

Classified as: auditory response, Sound, Motor signals, Sound perception, MNI, Montreal Neurological Institute & Hospital, science, External, staff, students, faculty
Published on: 6 Oct 2017

Lawyers representing both sides in concussion lawsuits against sports leagues may eventually have a new tool at their disposal: a diagnostic signature that uses artificial intelligence to detect brain trauma years after it has occurred. 

Classified as: Montreal Neurological Institute and Hospital (The Neuro), MNI, Research News, Athletics, concussion in athletics, External, faculty, MRI, staff, students, Sports, concussions
Published on: 12 Jul 2017

Much work to be done to improve diagnosis and treatment

When NHL star player Sidney Crosby suffered a concussion during a game in May – the fourth concussion of his career – the news made nationwide headlines. A few years earlier, a concussion had kept the Pittsburgh Penguins star off the ice for ten months.

Concussions can have serious consequences, even in cases where the victim shows few symptoms immediately. Victims often shrug off a mild blow to the head, unaware that brain damage has occurred.

Classified as: mental health, MNI, Neuro, Neurology, medicine research, football, Sports, concussions
Published on: 7 Jun 2017

Deep learning transforming neuroscience research

In an article published in Nature on Feb. 15, 2017, researchers, including principal investigators from the Montreal Neurological Institute’s McConnell Brain Imaging Centre (BIC), used magnetic resonance imaging (MRI) to predict the development of autism in babies.

Classified as: MNI, autism, Neuro, Sylvain Baillet, BIC, neuroimaging, brain imaging centre, deep learning
Published on: 20 Mar 2017

Discovery could be key to treating brain and spinal cord injury

A foray into plant biology led one researcher to discover that a natural molecule can repair axons, the thread-like projections that carry electrical signals between cells. Axonal damage is the major culprit underlying disability in conditions such as spinal cord injury and stroke.

Classified as: MNI, Neuro, Neurology, stroke, spinal cord injury, axon repair, 14-3-3, Fusicoccin-A
Published on: 8 Mar 2017

Dec. 1 is World AIDS Day, a time to raise awareness about a disease that has afflicted 70 million people worldwide, 35 million of whom have died as a result.

When most people think of AIDS, they generally do not think of a neurological disease, yet HIV infection can have an important impact on brain function. Untreated, HIV can cause severe dementia.

Classified as: MNI, Lesley Fellows, World AIDS Day, Department of Neurology & Neurosurgery
Published on: 30 Nov 2016

McGill Newsroom

Chemicals found to improve low-light vision of tadpoles by sensitizing retinal cells

A multidisciplinary team including researchers from the Montreal Neurological Institute has improved our understanding of how cannabinoids, the active agent in marijuana, affect vision in vertebrates.

Classified as: Montreal Neurological Institute, MNI, tadpoles, vision, marijuana, health and lifestyle, cannabis, vertebrates, RGC, CB1R
Published on: 25 Aug 2016

McGill Newsroom

Neuron cell death may be caused by overactive immune system 

A team of scientists led by Dr. Michel Desjardins from the University of Montreal and Dr. Heidi McBride from the Montreal Neurological Institute and Hospital (MNI) at McGill University have discovered that two genes associated with Parkinson's disease (PD) are key regulators of the immune system, providing direct evidence linking Parkinson's to autoimmune disease.

Classified as: neuroscience, MNI, lupus, Montreal Neurological Institute and Hospital, neurons, diabetes, sclerosis, neuroproject, neuroprojects, autoimmune disease, PINK1, Parkin, Parkinson's diease, PD, autoimmune, type 1 diabetes, rheumatoid arthritis
Published on: 28 Jun 2016

McGill Newsroom

Couche-Tard founder gives $4 million to McGill for groundbreaking research on intellectual disabilities

Classified as: Montreal Neurological Institute, MNI, couche-tard, intellectual disabilities, ID, Sandra Bouchard, Alain Bouchard, Sainte-Justine
Published on: 22 Jun 2016

McGill Newsroom

It’s all math: How Professor Alan Evans is using cutting-edge statistics to unravel the complexity of brain disorders.

When Alan Evans was starting out in the 1970s, researchers didn’t ask the boss to foot their bar tab. But that’s exactly what some of the coders in his Montreal Neurological Institute lab recently proposed: a 9-to-5 Saturday hackathon, held in an Irish pub a few blocks from the McGill University campus.

Classified as: neuroscience, Montreal Neurological Institute, MNI, Alan Evans, Simulation, neuroproject, neuroprojects, brain disorder, disorder
Published on: 20 Jun 2016

By the Media Relations Office, McGill Newsroom

Spotlight on neurosciences 

Neuroinformatics stands at the intersection of neuroscience and information science. One of the world leaders in this discipline is Prof. Pedro Valdes-Sosa, General Vice-Director for Research of the Cuban Neuroscience Center (CNEURO) which he co-founded in 1990.

Classified as: neuroscience, Montreal Neurological Institute, MNI, information science, science and technology, neuroproject, neuroprojects, podcast, Pedro Valdes-Sosa, neuroinformatics, Cuban Neuroscience Center, Havana
Published on: 2 Jun 2016

The Montreal Neurological Institute and Hospital (the Neuro) in Canada to conduct a radical experiment in open science.



Classified as: Guy Rouleau, Montreal Neurological Institute, MNI, Data sharing, open science
Published on: 12 May 2016

By Shawn Hayward, Montreal Neurological Institute and Hospital

Discovery will aid development of treatments for this debilitating disease

Scientists at the Montreal Neurological Institute and Hospital (MNI) have identified novel gene mutations that cause hereditary spastic paraplegia (HSP), a step forward in efforts to treat this debilitating disease.

Classified as: Guy Rouleau, MNI, Montreal Neurological Institute and Hospital, HSP, hereditary spastic paraplegia, gene mutation, debilitating disease, weakness, spasticity, CanHSP, Canadian Institutes for Health Research
Published on: 10 May 2016