Recent studies suggest that patients with frequent premature ventricular complexes (PVCs) are at a higher risk for cardiac myopathy and sudden cardiac death. However, risk stratification for these patients remains a significant challenge and the mechanism generating PVCs in a given patient is usually unclear. In this talk, we demonstrate how analysis of long ECGs with frequent PVCs reveal robust patterns in individual patients as a function of heart rate and time of day.
22Jan202111:00
to11:30
29Jan202111:00
to12:00
This presentation will review the role of the fungal exopolysaccharide galactosaminogalactan in the pathogenesis of invasive aspergillosis, the elucidation of the biosynthetic pathways governing the production of this virulence factor, and the development of novel therapeutic strategies targeting this important glycan.
This seminar will be given online via Zoom. Details in attached poster.
5Feb202111:00
to12:00
There is a need for developing treatments to stimulate bone formation in regenerative medicine since the approved drugs can only be used for a maximum of two years and have potential high risk side effects. Using FIAT (Factor Inhibiting ATF4 Mediated Transcription) as a target for drug development, we have developed a high-throughput assay that identified a lead compound (small molecule) for the development of drugs that could stimulate bone formation.
19Feb202111:00
to12:00
Immune cells and their derived molecules have major impact on brain function. Mice deficient in adaptive immunity have impaired cognitive and social function compared to that of wild-type mice. Importantly, replenishment of the T cell compartment in immune deficient mice restored proper brain function. We have identified several key T cell-derived cytokines that mediate the effect. Despite the robust influence on brain function, T cells are not found within the brain parenchyma, a fact that only adds more mystery into these enigmatic interactions between T cells and the brain.
7May202111:00
to12:00
This seminar will be given online via Zoom. Details in attached poster.
14May202115:30
to16:30
BIERMAN'S LECTURE
Plasticity of cancer invasion, metastasis and therapy response