Un événement commun se produit dans maintes pathologies du système nerveux : des cellules microgliales, qui sont des sentinelles chargées de surveiller, se muent en combattantes. Cellules immunitaires du système nerveux, les microglies ingèrent et détruisent des agents pathogènes et des cellules nerveuses lésées. Bien que ce processus soit crucial dans l’organisme, on savait jusqu’à présent très peu au sujet des mécanismes moléculaires d’activation des microglies.
In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters. Microglia are the immune cells of the nervous system, ingesting and destroying pathogens and damaged nerve cells. Until now little was known about the molecular mechanisms of microglia activation despite this being a critical process in the body.
International study with researchers at The Neuro reveals links with other neurodegenerative diseases MONTREAL, October 9, 2012 - Scientists at the Montreal Neurological Institute and Hospital – The Neuro, McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders. Using a new technique that has revolutionized genetic studies, the teams determined that mutations in the RMND1 gene were responsible for severe neurodegenerative disorders, in two infants, ultimately leading to thei
Genes predict the brain’s reaction to smoking Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes. A study from the Montreal Neurological Institute and Hospital - The Neuro, McGill University shows that people with genetically fast nicotine metabolism have a significantly greater brain response to smoking cues than those with slow nicotine metabolism.
Have you ever wondered why some people find it so much easier to stop smoking than others? New research shows that vulnerability to smoking addiction is shaped by our genes. A study from the Montreal Neurological Institute and Hospital - The Neuro, McGill University shows that people with genetically fast nicotine metabolism have a significantly greater brain response to smoking cues than those with slow nicotine metabolism. Previous research shows that greater reactivity to smoking cues predicts decreased success at smoking cessation and that environmental cues promote increased nicotine intake in animals and humans. This new finding that nicotine metabolism rates affect the brain’s response to smoking may lead the way for tailoring smoking cessation programs based on individual genetics.<!--break-->
Two projects led by McGill professors are among the 17 that will receive a total of $28 million over six years to help science and engineering graduates add job skills to their academic achievements, thanks to the Natural Sciences and Engineering Research Council of Canada’s (NSERC) CREATE program.
Creativity, teamwork, determination (possibly accompanied by blood, sweat and tears) are some of the skills honed by grade 6 – 8 students participating in the All Science Challenge, a unique, one-day, highly charged competition hosted by Let’s Talk Science on May 25 at The Neuro- the Montreal Neurological Institute and Hospital of McGill University and the McGill University Health Centre.
“Don’t be safe, be brilliant” a saying by philosopher George Santayana was a favourite of world-renowned scientist Dr. David Colman, late director of the Montreal Neurological Institute and Hospital at McGill University and McGill University Health Centre.
More than 50 members of The Neuro's staff are conducting laboratory and clinical studies related to MS. They employ the finest scientific equipment--from brain imaging scanners to the latest cell biology tools-to study the disease in all its aspects and at every stage. The Neuro's basic scientists and clinical physicians cooperate closely to translate research into patient therapies.
Now, a new review of human brain imaging studies published by Cell Press in the journal Trends in Endocrinology and Metabolism suggests that a major reason for the dramatic increase in obesity may be a heightened sensitivity to heavily advertised and easily accessible high-calorie foods.
A cholesterol drug commonly prescribed to reduce cardiovascular disease risk restores blood vessel function in a mouse model of Alzheimer’s disease, according to a study in the April 4 issue of The Journal of Neuroscience.