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Times of India - Red wine, vitamins don't really boost longevity

Published: 7 July 2010

Thought taking antioxidants via red wine and vitamins would increase your chances of living longer? Well, not really — a new study casts doubt on the theory that oxidative stress to our tissues shortens lifespan.

Researchers from McGill University have identified mutations in 10 different genes of worms (genes believed to have counterparts in humans) that extend their lifespan without reducing the level of oxidative stress the worms suffer. The results contradict the popular theory that production of toxic reactive oxygen species in tissues is responsible for aging.

"We hope that our study will help in tempering the undue emphasis put on the notion that oxidative stress causes aging and thus that antioxidants could combat aging," said Dr. Siegfried Hekimi, the senior author of the study from the Department of Biology at McGill University in Montreal. "We also hope that the genes we have discovered can be used in the future to modulate energy metabolism in a way that can help delay the health issues linked to aging, and possibly increase lifespan itself,” he added. The study has been published in the latest issue of the journal Genetics.

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