Grinding Chemicals Together in an Effort to be Greener

News

Published: 18Jul2016

...In 2011, the mechanochemist Tomislav Friscic and his team used mechanochemical methods to make bismuth subsalicylate, the active ingredient of Pepto-Bismol, by grinding together bismuth oxide and salicylic acid. The method not only does away with solvents, but also uses bismuth oxide, a safe reagent, in lieu of toxic bismuth salts.

In 2013, Dr. Friscic reported a new single-step process to prepare sulfonylguanidines, a family of chemicals used in herbicides and pharmaceuticals, through grinding. His research team at McGill University in Montreal tried to reproduce the process in solution, but failed. New York Times

Back to top