Killam Seminar Series: Digging Deep: Uncovering Hidden Connections Between Epilepsy and Alzheimer’s Disease


Speaker: Alice Lam, MD, PhD

Assistant Professor of Neurology, Harvard Medical School and Massachusetts General Hospital, Boston, USA

Registration: available now on Eventbrite

Livestreaming via Vimeo: Vimeo

Abstract: An emerging hypothesis in the field of Alzheimer’s disease (AD) is that neuronal hyperexcitability and other forms of aberrant network activity play an important role in shaping the clinical course of AD. In this talk, Dr. Lam will highlight the close and bi-directional relationships between epilepsy and AD, noting recent advances in our understanding of this topic spanning from animal models to humans. She will describe recent intracranial electrode recordings in humans that have revealed silent hippocampal epileptiform activity occurring in early stages of AD. Finally, she will discuss machine learning approaches that her laboratory has been developing to non-invasively diagnose and quantify silent hippocampal epileptiform activity from scalp EEG recordings.

The Killam Seminar Series at The Neuro

Supported by the generosity of the Killam Trusts, The Neuro’s Killam Seminar series hosts outstanding guest speakers whose research is of interest to the scientific community at The Neuro and McGill University.

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Contact Information

Sasha Kelly
Montreal Neurological Institute-Hospital
sasha.kelly [at]
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