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Pair of proteins found to drive neuroinflammation


Study could pave way for development of novel therapeutic approaches for inflammatory diseases
Tue, 2016-10-11 11:53

McGill researchers have identified two proteins that work together to drive neuroinflammation in acute conditions such as microbial or autoimmune encephalitis, and in chronic conditions such as multiple sclerosis. 

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Contact: Cynthia Lee
Organization: McGill University
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Office Phone: 514-398-6754
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Source Site: /newsroom

Virtual protein engineering towards improved biocatalysts

Sat, 2016-01-09 22:45

As part of a new venture in the Moitessier research group, recent Ph.D graduate, Josh Pottel, has delved into developing software to guide protein engineering. Computers can be used to simulate the shape and function of a protein or enzyme, but need the correct tools to be able to create accurate models. An initial platform for generating and applying new side-chain (rotamer) libraries has shown promise as the foundation for a biocatalysis prediction software.

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Contact: Nicolas Moitessier
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Source Site: /chemistry

Understanding the barrier protecting the brain

Protein that helps maintain the blood-brain barrier gives hope for MS
Wed, 2015-04-22 10:00

The brain is a privileged organ in the body. So vital to life, the brain is protected from alterations elsewhere in the body by a highly regulated gateway known as the blood-brain barrier, which allows only selected molecules to pass through.

Contact Information

Contact: Chris Chipello
Organization: McGill Media Relations Office
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Office Phone: 514.398.4201
Source Site: /newsroom

Unleashing the watchdog protein

Thu, 2013-05-09 14:38

Research opens door to new drug therapies for Parkinson’s disease

McGill University researchers have unlocked a new door to developing drugs to slow the progression of Parkinson’s disease. Collaborating teams led by Dr. Edward A. Fon at the Montreal Neurological Institute and Hospital -The Neuro, and  Dr. Kalle Gehring  in the Department of Biochemistry at the Faculty of Medicine, have discovered the three-dimensional structure of the protein Parkin.

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Contact: Anita Kar
Organization: The Neuro
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Office Phone: 514 398 3376
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