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Des sentinelles silencieuses veillent à la défense du système nerveux

Mon, 2012-10-15 09:13

Un événement commun se produit dans maintes pathologies du système nerveux : des cellules microgliales, qui sont des sentinelles chargées de surveiller, se muent en combattantes.  Cellules immunitaires du système nerveux, les microglies ingèrent et détruisent des agents pathogènes et des cellules nerveuses lésées. Bien que ce processus soit crucial dans l’organisme, on savait jusqu’à présent très peu au sujet des mécanismes moléculaires d’activation des microglies.


Attack! Silent watchmen charge to defend the nervous system

Mon, 2012-10-15 08:55

In many pathologies of the nervous system, there is a common event - cells called microglia are activated from surveillant watchmen into fighters.  Microglia are the immune cells of the nervous system, ingesting and destroying pathogens and damaged nerve cells. Until now little was known about the molecular mechanisms of microglia activation despite this being a critical process in the body.

Contact Information

Contact: Anita Kar
Organization: The Neuro
Office Phone: 5143983376

Scientists discover gene behind rare disorders

Tue, 2012-10-09 10:07

International study with researchers at The Neuro reveals links with other neurodegenerative diseases

MONTREAL, October 9, 2012  - Scientists at the Montreal Neurological Institute and Hospital – The Neuro,  McGill University working with a team at Oxford University have uncovered the genetic defect underlying a group of rare genetic disorders. 

Using a new technique that has revolutionized genetic studies, the teams determined that mutations in the RMND1 gene were responsible for severe neurodegenerative disorders, in two infants, ultimately leading to thei