Research on elderly rats suggests possible avenue for prevention of osteoporosis
Faleh Tamimi, is the leader of a research team that has just discovered that melatonin supplements make bones stronger in elderly rats and therefore, potentially, in elderly humans too. “Old rats are tedious to work with because they get sick a lot and that means they also cost a lot more. But if you’re interested in diseases like osteoporosis, they’re an essential part of the process.”
CIHR Canada Graduate Scholarships - MSc program
- Sandrine Couldwell, "The effect of exercise and high fat diet on circulating mediators of energy metabolism" (Kaartinen Lab)
- Yekta Ansari, "The role of salivary trace elements in tooth homeostasis" (Tamimi Lab)
A team led by McGill University’s Dr Michael H Weber, and Professor Jake Barralet, are developing a new technology with a 3D printer which seeks to create replicas of bone for spinal grafts. The concept creates a bone-like replacement material in the exact shape of bone or bone segment which is to be removed. Professor Barralet holds the Canada Research Chair in osteoinductive biomaterials.
It gives us great pleasure to announce that Dr. Luda Diatchenko will be joining the Faculties of Dentistry and Medicine as the holder of a Canada Excellence Research Chair (CERC) in Human Pain Genetics. The announcement was made On September 25th at McGill University by the Federal Government Minister of State for Science and Technology, Mr. Greg Rickford. The award will see $10millon in federal funds and another $20million in matching provincial and private funds over the next 7 years coming to support the research of Dr.
Dieter Reinhardt, of the Faculties of Dentistry and Medicine, was recently awarded a Canada Research Chair in Cell-Matrix Biology. Congratulations Dr. Reinhardt!
Betty Hoac, PhD student (supervisor Dr. Marc McKee, co-supervisor Dr. Monzur Murshed) wins 2-year FRQS studentship for her research on regulation of mineralization in bones and teeth.
David Wright, Postdoctoral Fellow (co-supervised by Dr. Mary Ellen Macdonald and Dr. Jennifer Fishman) wins 2-year FRQS fellowship for his research on ethical issues in end-of-life care to better understand nursing practice with patients who desire death.
Last week, Dr. Jocelyne Feine was honoured with IADR’s Distinguished Service Award in Seattle, WA. The award is presented to an individual member of the International Association for Dental Research (IADR) for outstanding instances of service to the Association or distinguished service over a period of time. It is intended to recognize members who have not served as officers of the IADR official. Read the official press release here.
Elusive substrate protein identified in the most common form of heritable rickets
Diagnosed in toddlers, X-linked hypophosphatemia (XLH) is the most common form of heritable rickets, in which soft bones bend and deform, and tooth abscesses develop because infections penetrate soft teeth that are not properly calcified. Researchers at McGill University and the Federal University of Sao Paulo have identified that osteopontin, a major bone and tooth substrate protein, plays a role in XLH. Their discovery may pave the way to effectively treating this rare disease.
The team led by Prof. Laura Stone, a professor at the Faculty of Dentistry and the Alan Edwards Centre for Research on Pain, and Prof. Moshe Szyf, a professor at the Faculty of Medicine’s Department of Pharmacology and Therapeutics, have discovered a mechanism that embeds the memory of an injury in the way the DNA is marked in the brain by a chemical coating called methyl groups or DNA methylation.
Professors Marc McKee (as lead investigator), Jake Barralet and Maryam Tabrizian, along with Hojatollah Vali as Director of the Facility for Electron Microscopy Research (FEMR) and six others, have received funding for a new cryo-focused ion beam scanning electron microscope. This nanotechnology instrument allows artifact-free sectioning of essentially any hard or soft material ‒ particularly frozen biological cells and tissues including bones and teeth ‒ for correlative microscopies and 3D ultrastructural and molecular reconstructions.