John Orlowski


Department:   Physiology

Appointments:  Professor; Chair, Department of Physiology; James McGill Prof.

Research:  The Orlowski lab focuses on Na+/H+ exchangers (NHEs) to understand the dynamics of cellular acid-base (pH) homeostasis. Current studies are addressing a variety of aims: (1) to define the transmembrane domains of the various NHEs; (2) to define the protein sorting and signaling mechanisms that underlie the membrane targeting and regulation of the NHEs; (3) to evaluate the physiological and pathophysiological contributions of certain NHEs to neuronal cell function, health and disease.

E-mail:  john.orlowski [at]


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