Hugo Salmon, Ph.D.

hugo.salmon [at] mcgill.ca

 

Education

PhD in Physics from Université Paris Sud: “Mobile Magnetic Microrobots Control and Study in Microfluidic Environment : New Tools for Biomedical Applications”.

Biomedical DUFBSM from Cancer institute Gustave Roussy, Université Paris Sud.

Engineer from Ecole Centrale de Lille, major in waves, nanoelectronics and telecom.

Research interests

My research work is dedicated to build bridges between micro / nanotechnology and health sciences, taking advantage of microfluidic devices and analytical methods. Here at Biomat’X, I am contributing to develop whole microbiotes detection and quantification taking advantage of microfluidics, aptamer and SPRi. Bacteria in food and water has become a growing society concern as WHO recent report has driven regulation tighter. New methods with faster and lower limit of detection are required. Taking advantage of SPR label-free straightforward detection and microfluidics enhanced analytical performances, we are pushing the limits of detection as well as increasing specificity and analysis throughput.

During my thesis work, I focused on microrobotic mobile transducer for microbiology applications as well as microrobots dynamics analysis. The microfluidics provided a development environment as well as a ground for new applications. I then investigated nanovectors developments for hepatic imaging applications. Microfluidics becoming a key enable in nanomedicines clinical translation, I developed characterization using hyphenated methods combining fluidic separative methods and physical detection. I developed separative methods taking advantages of field flow flow fractionation for aggregation and conjugates quantification as well as size distribution analysis.

I am deeply convinced in the virtue of collaboration between academic world and industry in applied sciences. I have been collaborating with several SME partners (Eden Microfluidics, Black Hole Laboratory, Wyatt Technology France) with whom I have intended to maintain a virtuous circle of development for microfabrication, material and analytical method development. 

I welcome any question concerning my former work but also research fields and interests - closely related or not.

Keywords: MEMS for health, lab on chip, analytical chemistry, microrobotics, nanomedicines, microfabrication.

Publications

  • H. Salmon, L. Couraud, G. Hwang, “Microrobot-in-glass for dynamic motion analysis and wider in vitro applications”, in Micro and Nano Letters, 2019.
  • H. Salmon, R. Gahoual, P. Houzé, T. Ibrahim, M. Bessodes, D. Scherman, J. Seguin, N. Mignet, “Europium labelled lactosylated albumin as a model workflow for the development of biotherapeutics”, in Nanomedicine: Nanotechnology, Biology and Medicine, Feb. 2019.
  • H. Salmon, L. Couraud, C. Roblin, G. Hwang, “On-chip mobile microrobotic transducer for high-temporal resolution sensing using dynamics analysis”, in Sensors and Actuators A: Physical, vol. 288, pp. 27-38, Apr. 2019.
  • K. Lemdani, H. Salmon, R. Gahoual, M. Bessodes, D. Scherman, P. Houzé, J. Seguin, N. Mignet, “Assessment of the targeting specificity of a fluorescent albumin conceived as a preclinical agent of the liver function”, in Nanoscale, vol. 10, no. 45, pp. 21151-21160, Nov. 2018.
  • J. Lachaux, H. Salmon, F. Loisel, N. Arouche, I. Ochoa, L. Fernandez, G. Uzan, O. Mercier, T. Veres, E. Roy, “Soft Thermoplastic Elastomer for Easy and Rapid Spin-Coating Fabrication of Microfluidic Devices with High Hydrophilization and Bonding Performances”, in Advanced Materials Technologies, vol. 4, no. 2, p. 1800308, 2019.
  • H. Salmon, L. Couraud, C. Roblin and G. Hwang, “Glass-metal-glass microfluidic chip for on-chip mobile microrobotic applications”, under review.
  • K. Lemdani, H. Salmon, R. Gahoual, M. Bessodes, D. Scherman, P. Houzé, J. Seguin, N. Mignet, “Liver function imaging with lactosylated labelled human albumin. Pre-clinical demonstration in a mice model of metastatic liver from colorectal cancer”, under review.
  • H. Salmon, R. Gahoual, N. Mignet, P. Houze, “Microfluidic asymmetric flow field flow fraction device and method”, European Patent, EP18305185, 2018.
  • C. Perrault, H. Salmon, Olaf Mercier, Emmanuel Roy, “Insights on Polymers for Microfluidics Applied to Biomedical Applications”, Res Rev Polym, vol. 8, no. 1, p. 106, 2017.
  • Hwang, G. et al. Mobile microrobotic manipulator in microfluidics. Sensors Actuators, A: Physical 215, pp. 56–64, 2014.
  • H. Salmon, L. Couraud, and G. Hwang, “Using breakdown phenomenon as mobile magnetic field sensor in microfluidics,” in 2013 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), pp. 2041–2046, 2013.
  • H. Salmon, L. Couraud, and G. Hwang, “Swimming property characterizations of Magnetic Polarizable microrobots” IEEE International Conference on Robotics and Automation (ICRA), pp. 5520–5526, 2013.

Conferences

  • "Europium labelled lactosylated albumin as a daily laboratory practice for liver  targeting pre-evaluation", H. Salmon, J. Seguin, R. Gahoual, M. Bessodes, N. Mignet, French society for nanomedecines SFNano 2017.
  • “Bimodal imaging to ease the development of nanomedicines” H. Salmon, K. Lemdani, J. Seguin, S. Manta, BT Doan, F. Lux, O. Tillement, G. Renault, A. Delalande, C. Pichon, N. Mignet, Le Studium Conferences, 2017.
  • (oral) “Glass-Metal-Glass Microfluidic Chip for Moible Microrobotic and Applications» H. Salmon, L. Couraud, C. Roblin and G. Hwang, 40th Intl Conf. on Micro and Nano Engineering (MNE), 2014.
  • (oral) H. Salmon, L. Couraud, and G. Hwang, “Using breakdown phenomenon as mobile magnetic field sensor in microfluidics,” in 2013 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), pp. 2041–2046, 2013.
  • (oral) H. Salmon, L. Couraud, and G. Hwang, “Swimming property characterizations of Magnetic Polarizable microrobots” IEEE International Conference on Robotics and Automation (ICRA), pp. 5520–5526, 2013
  • “Large range versatile wireless Micro-robotic Manipulators in Microfluidic Devices” G. Hwang, H. Salmon, I. A. Ivan, J. A., N. Chaillet, S. Régnier, A.-M. Haghiri-Gosnet, IEEE 26th Intl Conf. on Micro Electro Mechanical Systems (MEMS), 2013.
  • “Fabrication and Characterization of Ultra-fast Thin-film Microrobots” G. Hwang, H. Salmon, L. Couraud, N. Allemandou, E. Cambril, L. Ferlazzo, D. Decanini, 38th Intl Conf. on Micro and Nano Engineering (MNE), 2012.
  • “Remotely powered floating microswimmers as colloidal microparticle manipulators” G. Hwang, H. Salmon,S. Haliyo, N. Chaillet, S. Régnier, A.-M. Haghiri-Gosnet, 37th Intl Conf. on Micro and Nano Engineering (MNE), 2011.

Awards and honors

  • Received at Agrégation de Mathématiques in 2016.
  • #1 at NIST& IEEE Micro Mobility Challenge 2014.
  • #1 at NIST& IEEE Micro Assembly Challenge 2013.

Additional information

Temporary teacher assistant at the University of Paris Descartes (2016-2018) in Analytical Chemistry and wet chemistry for Pharmacy students.

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