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Biomaterials Research Group

Research in biomaterials and biointerfaces combines knowledge of chemistry, physics, biology, biochemistry, and engineering. This makes research in this field challenging, interesting and rewarding.

The development of novel interfaces for the improved interaction of biomaterials with biological environment is the overall objective of our research. We aim to build a deeper understanding of cell-biomaterial interactions in order improve our ability to predict and control the host response to new materials. This is carried out through the design, fabrication and characterization of multifunctional and bioactive surfaces as well as through the development of methodologies and protocols for creating these new biointerfaces. Our motivation rises from our belief that the future of biomedical devices will exploit materials surfaces that are designed on the basis of engineering principles to mimic the way that nature does it. As such, our laboratory masters a broad expertise in surface modification techniques, namely chemical, molecular assembly and biological methods to cope with the highly divergent requirements for surface properties in biomedical applications. Our target applications are mainly focused on regenerative medicine, nanomedicine and Lab-on-a-Chip platforms.

In the Biomat'X Research Laboratories, projects covering a broad range of topics are currently in progress. Some of these areas include:

  • Cell-cell and cell-biomaterial interactions.
  • Layer-by-Layer self-assembly as bioactive interface on artificial and biological nanoparticulate templates for imaging, molecular therapy and tissue engineering.
  • 3D and 2D biocompatible hydrogels and sponges for molecular therapy and tissue engineering.
  • Surface molecular engineering and nanopatterning for biorecognition systems
  • Microfluidic platform and Lab-on-a-Chip devices for genomic, proteomic, cell sorting and cell culturing.
  • Non-invasive and real-time assessment of cell and tissue growth in microenvironment