Publications

2023

Yedire, S. G. et al. Additive manufacturing leveraged microfluidic setup for sample to answer colorimetric detection of pathogens. Lab Chip 23, 4134-4145 (2023). https://doi.org:10.1039/d3lc00429e

Yang, Z. et al. Development of an Integrated Continuous Manufacturing Process for the rVSV-Vectored SARS-CoV-2 Candidate Vaccine. Vaccines (Basel) 11 (2023). https://doi.org:10.3390/vaccines11040841

Yang, E. et al. The default network dominates neural responses to evolving movie stories. Nat Commun 14, 4197 (2023). https://doi.org:10.1038/s41467-023-39862-y

Wagner, C. E. et al. Comparison of Physicochemical Properties of Native Mucus and Reconstituted Mucin Gels. Biomacromolecules 24, 628-639 (2023). https://doi.org:10.1021/acs.biomac.2c01016

Smith, K. S., Kinsella, E. A., Moodie, S., McCorquodale, L. & Teachman, G. Mindfulness in paediatric occupational therapy practice: a phenomenological inquiry. Disabil Rehabil, 1-9 (2023). https://doi.org:10.1080/09638288.2023.2214380

Smith, K. S., Kinsella, E. A., Moodie, S., McCorquodale, L. & Teachman, G. Mindfulness and therapeutic relationships: A phenomenological inquiry into paediatric occupational therapists' practices. Scand J Occup Ther, 1-10 (2023). https://doi.org:10.1080/11038128.2023.2217670

Siavash Moakhar, R. et al. Aptamer-Based Electrochemical Microfluidic Biosensor for the Detection of Cryptosporidium parvum. ACS Sens 8, 2149-2158 (2023). https://doi.org:10.1021/acssensors.2c01349

Shams, S., Prokopiou, P., Esmaelbeigi, A., Mitsis, G. D. & Chen, J. J. Modeling the dynamics of cerebrovascular reactivity to carbon dioxide in fMRI under task and resting-state conditions. Neuroimage 265, 119758 (2023). https://doi.org:10.1016/j.neuroimage.2022.119758

Shafique, H. et al. Advances in the Translation of Electrochemical Hydrogel-Based Sensors. Adv Healthc Mater 12, e2201501 (2023). https://doi.org:10.1002/adhm.202201501

Sene, M. A., Xia, Y. & Kamen, A. A. Comparative Transcriptomic Analyses of a Vero Cell Line in Suspension versus Adherent Culture Conditions. Int J Cell Biol 2023, 9364689 (2023). https://doi.org:10.1155/2023/9364689

Saad-Roy, C. M. et al. Medium-term scenarios of COVID-19 as a function of immune uncertainties and chronic disease. J R Soc Interface 20, 20230247 (2023). https://doi.org:10.1098/rsif.2023.0247

Prowse, E. N. P., Chaudhary, A. R., Sharon, D. & Hendricks, A. G. Huntingtin S421 phosphorylation increases kinesin and dynein engagement on early endosomes and lysosomes. Biophys J 122, 1168-1184 (2023). https://doi.org:10.1016/j.bpj.2023.02.006

Panerai, R. B. et al. Transfer function analysis of dynamic cerebral autoregulation: A CARNet white paper 2022 update. J Cereb Blood Flow Metab 43, 3-25 (2023). https://doi.org:10.1177/0271678X221119760

O'Connor, D., Chang, C. & Mitsis, G. D. Editorial: Advancing the measurement, interpretation, and validation of dynamic functional connectivity. Front Hum Neurosci 17, 1206098 (2023). https://doi.org:10.3389/fnhum.2023.1206098

Normandin, K. et al. Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations. PLoS Genet 19, e1010903 (2023). https://doi.org:10.1371/journal.pgen.1010903

Nithianantham, S. et al. The kinesin-5 tail and bipolar minifilament domains are the origin of its microtubule crosslinking and sliding activity. Mol Biol Cell 34, ar111 (2023). https://doi.org:10.1091/mbc.E23-07-0287

Ni, Z. et al. Guiding the choice of informatics software and tools for lipidomics research applications. Nat Methods 20, 193-204 (2023). https://doi.org:10.1038/s41592-022-01710-0

Moco, P. D., Xu, X., Silva, C. A. T. & Kamen, A. A. Production of adeno-associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities. Biotechnol J 18, e2300051 (2023). https://doi.org:10.1002/biot.202300051

Melnyk, A., Kozarov, L. & Wachsmann-Hogiu, S. A deconvolution approach to modelling surges in COVID-19 cases and deaths. Sci Rep 13, 2361 (2023). https://doi.org:10.1038/s41598-023-29198-4

Leyland, Z. A., Walton, D. M. & Kinsella, E. A. Two Puzzles, a Tour Guide, and a Teacher: The First Cohorts' Lived Experience of Participating in the MClSc Interprofessional Pain Management Program. Healthcare (Basel) 11 (2023). https://doi.org:10.3390/healthcare11101397

LeBlanc-Omstead, S. & Kinsella, E. A. "Come and share your story and make everyone cry": complicating service user educator storytelling in mental health professional education. Adv Health Sci Educ Theory Pract 28, 387-410 (2023). https://doi.org:10.1007/s10459-022-10157-z

Koushki, N., Ghagre, A., Srivastava, L. K., Molter, C. & Ehrlicher, A. J. Nuclear compression regulates YAP spatiotemporal fluctuations in living cells. Proc Natl Acad Sci U S A 120, e2301285120 (2023). https://doi.org:10.1073/pnas.2301285120

Kort-Mascort, J. et al. Bioprinted cancer-stromalin-vitromodels in a decellularized ECM-based bioink exhibit progressive remodeling and maturation. Biomed Mater 18 (2023). https://doi.org:10.1088/1748-605X/acd830

Kort-Mascort, J. et al. Decellularized ECM hydrogels: prior use considerations, applications, and opportunities in tissue engineering and biofabrication. Biomater Sci 11, 400-431 (2023). https://doi.org:10.1039/d2bm01273a

Koopman, W. J., LaDonna, K. A., Kinsella, E. A., Venance, S. L. & Watling, C. J. Archetypes of incomplete stories in chronic illness medical encounters. Patient Educ Couns 117, 107973 (2023). https://doi.org:10.1016/j.pec.2023.107973

Kleiner, M. J. et al. An integrative review of the qualities of a 'good' physiotherapist. Physiother Theory Pract 39, 89-116 (2023). https://doi.org:10.1080/09593985.2021.1999354

Karakis, R., Gurkahraman, K., Mitsis, G. D. & Boudrias, M. H. Deep learning prediction of motor performance in stroke individuals using neuroimaging data. J Biomed Inform 141, 104357 (2023). https://doi.org:10.1016/j.jbi.2023.104357

Jin, Z., Vighi, A., Dong, Y., Bureau, J. A. & Ignea, C. Engineering membrane architecture for biotechnological applications. Biotechnol Adv 64, 108118 (2023). https://doi.org:10.1016/j.biotechadv.2023.108118

Jalali, M. et al. MoS(2)-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma. ACS Nano 17, 12052-12071 (2023). https://doi.org:10.1021/acsnano.2c09222

Heidari Nia, M. et al. Internally bridged nanosilica for loadings and release of sparsely soluble compounds. J Colloid Interface Sci 649, 456-470 (2023). https://doi.org:10.1016/j.jcis.2023.06.118

Heidari Nia, M., Ashkar, S., Munguia-Lopez, J. G., Kinsella, J. & van de Ven, T. G. M. Hairy Nanocellulose-Based Supramolecular Architectures for Sustained Drug Release. Biomacromolecules 24, 2100-2117 (2023). https://doi.org:10.1021/acs.biomac.2c01514

Guichaoua, L. et al. Using Combination of X-Ray 3D Tomography and FEG-SEM to Perform 3D-FIB Reconstruction in Identified Area to Investigate Effect of Mining Contamination on Scallop Shell Growth. Microsc Microanal 29, 560-561 (2023). https://doi.org:10.1093/micmic/ozad067.267

Gracia-Tabuenca, Z., Barbeau, E. B., Xia, Y. & Chai, X. Predicting depression risk in early adolescence via multimodal brain imaging. bioRxiv (2023). https://doi.org:10.1101/2023.04.10.536286

Flores-Torres, S. et al. Constructing 3D In Vitro Models of Heterocellular Solid Tumors and Stromal Tissues Using Extrusion-Based Bioprinting. ACS Biomater Sci Eng 9, 542-561 (2023). https://doi.org:10.1021/acsbiomaterials.2c00998

Flores-Torres, S. et al. Bioprinted Multicomponent Hydrogel Co-culture Tumor-Immune Model for Assessing and Simulating Tumor-Infiltrated Lymphocyte Migration and Functional Activation. ACS Appl Mater Interfaces 15, 33250-33262 (2023). https://doi.org:10.1021/acsami.3c02995

Dobroiu, S. et al. Spatially Addressable Multiplex Biodetection by Calibrated Micro/Nanostructured Surfaces. ACS Sens 8, 1882-1890 (2023). https://doi.org:10.1021/acssensors.2c01939

Dimitriou, N. M., Flores-Torres, S., Kinsella, J. M. & Mitsis, G. D. Detection and Spatiotemporal Analysis of In-vitro 3D Migratory Triple-Negative Breast Cancer Cells. Ann Biomed Eng 51, 318-328 (2023). https://doi.org:10.1007/s10439-022-03022-y

Del Real Mata, C., Jeanne, O., Jalali, M., Lu, Y. & Mahshid, S. Nanostructured-Based Optical Readouts Interfaced with Machine Learning for Identification of Extracellular Vesicles. Adv Healthc Mater 12, e2202123 (2023). https://doi.org:10.1002/adhm.202202123

Dash, S. et al. A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing. Protein Expr Purif 210, 106295 (2023). https://doi.org:10.1016/j.pep.2023.106295

Bustos, N. A., Ribbeck, K. & Wagner, C. E. The role of mucosal barriers in disease progression and transmission. Adv Drug Deliv Rev 200, 115008 (2023). https://doi.org:10.1016/j.addr.2023.115008

Buss, D. J., Rechav, K., Reznikov, N. & McKee, M. D. Mineral tessellation in mouse enthesis fibrocartilage, Achilles tendon, and Hyp calcifying enthesopathy: A shared 3D mineralization pattern. Bone 174, 116818 (2023). https://doi.org:10.1016/j.bone.2023.116818

Bureau, J. A., Oliva, M. E., Dong, Y. & Ignea, C. Engineering yeast for the production of plant terpenoids using synthetic biology approaches. Nat Prod Rep (2023). https://doi.org:10.1039/d3np00005b

Beaudet, D. & Hendricks, A. G. Reconstitution of Organelle Transport Along Microtubules In Vitro. Methods Mol Biol 2623, 113-132 (2023). https://doi.org:10.1007/978-1-0716-2958-1_8

Ayad, N. M. E., Lakins, J. N., Ghagre, A., Ehrlicher, A. J. & Weaver, V. M. Tissue tension permits beta-catenin phosphorylation to drive mesoderm specification in human embryonic stem cells. bioRxiv (2023). https://doi.org:10.1101/2023.07.14.549074

Aminzare, M. et al. Biomolecules incorporated in halide perovskite nanocrystals: synthesis, optical properties, and applications. Nanoscale 15, 2997-3031 (2023). https://doi.org:10.1039/d2nr05565a

Alberici Delsin, L. E. et al. MAP4K4 regulates forces at cell-cell and cell-matrix adhesions to promote collective cell migration. Life Sci Alliance 6 (2023). https://doi.org:10.26508/lsa.202302196

AbdElFatah, T. et al. Nanoplasmonic amplification in microfluidics enables accelerated colorimetric quantification of nucleic acid biomarkers from pathogens. Nat Nanotechnol 18, 922-932 (2023). https://doi.org:10.1038/s41565-023-01384-5

Tough Transient Ionic Junctions Printed with Ionic Microgels. (2023).

The androgen receptor as a potential regulator of prostate cancer contractility. (2023).

Tau acts as a selective barrier along microtubules to regulate multi-motor cargo transport. (2023).

Targeted Delivery of Chimeric Antigen Receptor into T Cells via CRISPR-Mediated Homology-Directed Repair with a Dual-AAV6 Transduction System. (2023).

Support Vector Machine for Color Classification of RNA. (2023).

SSCAE: A Neuromorphic SNN Autoencoder for sc-RNA-seq Dimensionality Reduction. (2023).

Resolving cadherin-mediated inter-cell contractile tension in multicellular migration. (2023).

Raman and SERS spectroscopy for EV characterization: detection of amyloid beta and bulk chemical analysis (Conference Presentation). (2023).

Production of adeno-associated viral vector serotype 6 by triple transfection of suspension HEK293 cells at higher cell densities. (2023).

Performing a Digital Nucleic Acid Test in a Nanofluidic Device with Pneumatic Confinement Control. (2023).

"Optogenetic control of kinesins-1,-2,-3, and dynein reveals their specific roles in vesicular transport". (2023).

Optogenetic control of kinesins and dynein reveals their specific roles in vesicular transport. (2023).

Optical Tweezers and Force Spectrum Microscopy. (2023).

On-Chip Rapid Impedimetric Detection of Viral Antibodies in Whole Blood. (2023).

On the variability of dynamic functional connectivity assessment methods. (2023).

Nanostructured?Based Optical Readouts Interfaced with Machine Learning for Identification of Extracellular Vesicles (Adv. Healthcare Mater. 5/2023). (2023).

"Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XX". (2023).

Nanoplasmonic acceleration of nucleic acid amplification for pathogen detection. Nat Nanotechnol 18, 846-847 (2023). https://doi.org:10.1038/s41565-023-01398-z

MoS2-Plasmonic Nanocavities for Raman Spectra of Single Extracellular Vesicles Reveal Molecular Progression in Glioblastoma. (2023).

"Mineral tessellation in mouse enthesis fibrocartilage, Achilles tendon, and Hyp calcifying enthesopathy: A shared 3D mineralization pattern". (2023).

Microfluidic-based colorimetric nucleic acid detection of pathogens. (2023).

Medium-term scenarios of COVID-19 as a function of immune uncertainties and chronic disease. (2023).

Medium-and high-cell-density production of Adeno-Associated virus serotype 6 and the mitigation of cell density effect via medium supplementation. (2023).

MDB-39. ASSESSMENT OF MEDULLOBLASTOMA PATIENTS THROUGH MONITORING EXTRACELLULAR VESICLES VIA SURFACE-ENHANCED RAMAN SPECTROSCOPY COMBINED WITH MACHINE LEARNING. (2023).

MAP4K4 regulates forces at cell–cell and cell–matrix adhesions to promote collective cell migration. (2023).

Huntingtin polyglutamine expansions impair the transport of signalling and degradative cargoes. (2023).

High-cell-density production of adeno-associated viral vector serotype 6 by triple transfection in suspension HEK293 cell cultures. (2023).

Electrochemiluminescence detection of uric acid at point-of-need by using a lab-on-a-CMOS platform (Conference Presentation). (2023).

Effects of 70Hz Transcranial Alternating Current Stimulation (tACS) on Movement-related Brainwaves and Associated Motor Task Performance: A Pilot Study. (2023).

Doublecortin regulates neuronal migration by editing the tubulin code. (2023).

"Decellularized ECM hydrogels: Prior use considerations, applications, and opportunities in tissue engineering and biofabrication". (2023).

"Corrigendum to “Assessing roughness of extrusion printed soft materials using a semi-quantitative method” [Mater. Lett. 303 (2021) 130480] (Materials Letters (2021) 303, (S0167577X21011770), (10.1016/j.matlet.2021.130480))". (2023).

Cancer cell sedimentation in 3D cultures reveals active migration regulated by self-generated gradients and adhesion sites. (2023).

Bioprinted cancer-stromal in-vitro models in a decellularized ECM-based bioink exhibit progressive remodeling and maturation. (2023).

"Biomolecules incorporated in halide perovskite nanocrystals: synthesis, optical properties, and applications". (2023).

An Electrochemical Aptamer-Based Biosensor Accompanied by a Portable and Smartphone-Operated Potentiostat for Point-of-Care Applications. (2023).

"Advancing the measurement, interpretation, and validation of dynamic functional connectivity". (2023).

Additively manufactured multiplexed electrochemical device (AMMED) for portable sample-to-answer detection. (2023).

"A rapid procedure to generate stably transfected HEK293 suspension cells for recombinant protein manufacturing: Yield improvements, bioreactor production and downstream processing". (2023).

A novel approach for quantifying active viscoelastic cellular mechanics using cardiomyocyte contractility. (2023).

A dual-index quality evaluation method for direct ink writing of soft materials. (2023).

"A calibration and uncertainty quantification analysis of classical, fractional and multiscale logistic models of tumour growth". (2023).

(Invited) Translational Applications of Nanostructured Biosensors: Diagnostics at the Point of Care. (2023).

 

2022

Yeung, K. K. et al. Utilizing Gradient Porous Graphene Substrate as the Solid-Contact Layer To Enhance Wearable Electrochemical Sweat Sensor Sensitivity. Nano Lett 22, 6647-6654 (2022). https://doi.org:10.1021/acs.nanolett.2c01969

Yang, Z. et al. Membrane Chromatography-Based Downstream Processing for Cell-Culture Produced Influenza Vaccines. Vaccines (Basel) 10 (2022). https://doi.org:10.3390/vaccines10081310

Yan, X., Boudrias, M. H. & Mitsis, G. D. Removal of Transcranial Alternating Current Stimulation EEG Artifacts Using Blind Source Separation and Wavelets. IEEE Trans Biomed Eng 69, 3183-3192 (2022). https://doi.org:10.1109/TBME.2022.3162490

Wondraczek, L. et al. Advancing the Mechanical Performance of Glasses: Perspectives and Challenges. Adv Mater 34, e2109029 (2022). https://doi.org:10.1002/adma.202109029

Wagner, C. E., Saad-Roy, C. M. & Grenfell, B. T. Modelling vaccination strategies for COVID-19. Nat Rev Immunol 22, 139-141 (2022). https://doi.org:10.1038/s41577-022-00687-3

Tsuzuki, T. et al. Hydrophobic Recovery of PDMS Surfaces in Contact with Hydrophilic Entities: Relevance to Biomedical Devices. Materials (Basel) 15 (2022). https://doi.org:10.3390/ma15062313

Tran, M. Y. & Kamen, A. A. Production of Lentiviral Vectors Using a HEK-293 Producer Cell Line and Advanced Perfusion Processing. Front Bioeng Biotechnol 10, 887716 (2022). https://doi.org:10.3389/fbioe.2022.887716

Sutton, A. A. et al. Cell monolayer deformation microscopy reveals mechanical fragility of cell monolayers following EMT. Biophys J 121, 629-643 (2022). https://doi.org:10.1016/j.bpj.2022.01.003

Siavash Moakhar, R. et al. A non-enzymatic photoelectrochemical sensor based on Co-Pi modified one-dimensional titanium oxide embedded microscale reactor. Biosensors and Bioelectronics: X 11 (2022). https://doi.org:10.1016/j.biosx.2022.100157

Siavash Moakhar, R. et al. A Versatile Biomimic Nanotemplating Fluidic Assay for Multiplex Quantitative Monitoring of Viral Respiratory Infections and Immune Responses in Saliva and Blood. Adv Sci (Weinh) 9, e2204246 (2022). https://doi.org:10.1002/advs.202204246

Shelvock, M., Kinsella, E. A. & Harris, D. Beyond the Corporatization of Death Systems: Towards Green Death Practices. Illn Crises Loss 30, 640-658 (2022). https://doi.org:10.1177/10541373211006882

Sene, M. A., Xia, Y. & Kamen, A. A. From functional genomics of vero cells to CRISPR-based genomic deletion for improved viral production rates. Biotechnol Bioeng 119, 2794-2805 (2022). https://doi.org:10.1002/bit.28190

Savva, A. D., Matsopoulos, G. K. & Mitsis, G. D. A Wavelet-Based Approach for Estimating Time-Varying Connectivity in Resting-State Functional Magnetic Resonance Imaging. Brain Connect 12, 285-298 (2022). https://doi.org:10.1089/brain.2021.0015

RS Moakhar, C. d. R. M., M Jalali, H Shafique, A Sanati, J de Vries, ... in 241st ECS Meeting (2022).

R Siavash Moakhar, C. d. R. M., H Shafique, M Jalali, J de Vries, ... (Digital Presentation) Biomimic Nanotemplating Assay Based on Molecularly Imprinted Polymers for the Impedimetric Detection of Sars-Cov-2 and Influenza A …. Electrochemical Society Meeting Abstracts 242, 2446-2446 (2022).

Prokopiou, P. C., Xifra-Porxas, A., Kassinopoulos, M., Boudrias, M. H. & Mitsis, G. D. Modeling the Hemodynamic Response Function Using EEG-fMRI Data During Eyes-Open Resting-State Conditions and Motor Task Execution. Brain Topogr 35, 302-321 (2022). https://doi.org:10.1007/s10548-022-00898-w

Pollet, L., Lambourne, L. & Xia, Y. Structural Determinants of Yeast Protein-Protein Interaction Interface Evolution at the Residue Level. J Mol Biol 434, 167750 (2022). https://doi.org:10.1016/j.jmb.2022.167750

Olivera-Ugarte, S. M. et al. A nanoparticle-based COVID-19 vaccine candidate elicits broad neutralizing antibodies and protects against SARS-CoV-2 infection. Nanomedicine 44, 102584 (2022). https://doi.org:10.1016/j.nano.2022.102584

Oceguera-Contreras, E. et al. Establishment of the upstream processing for renewable production of hydrogen using vermicomposting-tea and molasses as substrate. Waste Manag 139, 279-289 (2022). https://doi.org:10.1016/j.wasman.2021.12.027

Molter, C. W. et al. Prostate cancer cells of increasing metastatic potential exhibit diverse contractile forces, cell stiffness, and motility in a microenvironment stiffness-dependent manner. Front Cell Dev Biol 10, 932510 (2022). https://doi.org:10.3389/fcell.2022.932510

McKee, M. D., Buss, D. J. & Reznikov, N. Corrigendum to "Mineral tessellation in bone and the stenciling principle for extracellular matrix mineralization" [J. Struct. Biol. 214(1) (2022) 107823]. J Struct Biol 214, 107858 (2022). https://doi.org:10.1016/j.jsb.2022.107858

Mann-Krzisnik, D. & Mitsis, G. D. Extracting electrophysiological correlates of functional magnetic resonance imaging data using the canonical polyadic decomposition. Hum Brain Mapp 43, 4045-4073 (2022). https://doi.org:10.1002/hbm.25902

Liu, J. & Wachsmann-Hogiu, S. Progress and Challenges of Point-of-Need Photonic Biosensors for the Diagnosis of COVID-19 Infections and Immunity. Biosensors (Basel) 12 (2022). https://doi.org:10.3390/bios12090678

Leyland, Z. A., Walton, D. M. & Kinsella, E. A. "Maybe I would've been more comfortable in my Ignorance?": Exploring future physical therapist's lived experience of an elective pain science course. Physiother Theory Pract, 1-10 (2022). https://doi.org:10.1080/09593985.2022.2098213

Kleiner, M. J., Kinsella, E. A., Miciak, M., Teachman, G. & Walton, D. M. The 'responsive' practitioner: physiotherapists' reflections on the 'good' in physiotherapy practice. Physiother Theory Pract, 1-14 (2022). https://doi.org:10.1080/09593985.2022.2092567

Kleiner, M. J., Kinsella, E. A., Miciak, M., Teachman, G. & Walton, D. M. "Passion to do the right thing": searching for the 'good' in physiotherapist practice. Physiother Theory Pract, 1-16 (2022). https://doi.org:10.1080/09593985.2022.2116740

Kassinopoulos, M. & Mitsis, G. D. A multi-measure approach for assessing the performance of fMRI preprocessing strategies in resting-state functional connectivity. Magn Reson Imaging 85, 228-250 (2022). https://doi.org:10.1016/j.mri.2021.10.028

Kang'iri, S. M., Salem, A., Nicolau, D. V. & Nitta, T. Effects of defective motors on the active transport in biosensors powered by biomolecular motors. Biosens Bioelectron 203, 114011 (2022). https://doi.org:10.1016/j.bios.2022.114011

Imanbekova, M., Suarasan, S., Lu, Y., Jurchuk, S. & Wachsmann-Hogiu, S. Recent advances in optical label-free characterization of extracellular vesicles. Nanophotonics 11, 2827-2863 (2022). https://doi.org:10.1515/nanoph-2022-0057

Ignea, C. et al. Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks. Nat Commun 13, 5188 (2022). https://doi.org:10.1038/s41467-022-32921-w

Husain, A., Khadka, A., Ehrlicher, A., Saint-Geniez, M. & Krishnan, R. Substrate stiffening promotes VEGF-A functions via the PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun 586, 27-33 (2022). https://doi.org:10.1016/j.bbrc.2021.11.030

Harrison, H. F., Kinsella, E. A., DeLuca, S. & Loftus, S. "We know what they're struggling with": student peer mentors' embodied perceptions of teaching in a health professional education mentorship program. Adv Health Sci Educ Theory Pract 27, 63-86 (2022). https://doi.org:10.1007/s10459-021-10072-9

H Shafique, R. S. M., C del Real Mata, T Abdel Fatah, . (Digital Presentation) Development of an Electrochemical Microfluidic Device with on-Platform Sample Collection. Electrochemical Society Meeting Abstracts 241, 2191-2191 (2022).

Ghadie, M. A. & Xia, Y. Are transient protein-protein interactions more dispensable? PLoS Comput Biol 18, e1010013 (2022). https://doi.org:10.1371/journal.pcbi.1010013

Fulber, J. P. C. & Kamen, A. A. Development and Scalable Production of Newcastle Disease Virus-Vectored Vaccines for Human and Veterinary Use. Viruses 14 (2022). https://doi.org:10.3390/v14050975

Duarte, N. et al. Deploying wearable sensors for pandemic mitigation: A counterfactual modelling study of Canada's second COVID-19 wave. PLOS Digit Health 1, e0000100 (2022). https://doi.org:10.1371/journal.pdig.0000100

Dash, S., Sharon, D. M., Mullick, A. & Kamen, A. A. Only a small fraction of cells produce assembled capsids during transfection-based manufacturing of adeno-associated virus vectors. Biotechnol Bioeng 119, 1685-1690 (2022). https://doi.org:10.1002/bit.28068

Cario, A. et al. The pathogenic R5L mutation disrupts formation of Tau complexes on the microtubule by altering local N-terminal structure. Proc Natl Acad Sci U S A 119 (2022). https://doi.org:10.1073/pnas.2114215119

Cao, S. et al. Photoelectrochemical sensors based on heterogeneous nanostructures for in vitro diagnostics. Biosensors and Bioelectronics: X 11 (2022). https://doi.org:10.1016/j.biosx.2022.100200

Cable, J. et al. Innovative vaccine approaches-a Keystone Symposia report. Ann N Y Acad Sci 1511, 59-86 (2022). https://doi.org:10.1111/nyas.14739

Bustos, N. A., Saad-Roy, C. M., Cherstvy, A. G. & Wagner, C. E. Distributed medium viscosity yields quasi-exponential step-size probability distributions in heterogeneous media. Soft Matter 18, 8572-8581 (2022). https://doi.org:10.1039/d2sm00952h

Buss, D. J., Kroger, R., McKee, M. D. & Reznikov, N. Hierarchical organization of bone in three dimensions: A twist of twists. J Struct Biol X 6, 100057 (2022). https://doi.org:10.1016/j.yjsbx.2021.100057

Balabanian, L. et al. Tau differentially regulates the transport of early endosomes and lysosomes. Mol Biol Cell 33, ar128 (2022). https://doi.org:10.1091/mbc.E22-01-0018

Baker, R. E. et al. Infectious disease in an era of global change. Nat Rev Microbiol 20, 193-205 (2022). https://doi.org:10.1038/s41579-021-00639-z

Archer, R. M. & Kinsella, E. A. Phronesis in Veterinary Medicine: Navigating the Complexity of Practice with Wisdom. J Vet Med Educ, e20220094 (2022). https://doi.org:10.3138/jvme-2022-0094

Abbasi, R., Liu, J., Suarasan, S. & Wachsmann-Hogiu, S. SE-ECL on CMOS: a miniaturized electrochemiluminescence biosensor. Lab Chip 22, 994-1005 (2022). https://doi.org:10.1039/d1lc00905b

Vectored vaccines. (2022).

Utilizing gradient porous graphene substrate as the solid-contact layer to enhance wearable electrochemical sweat sensor sensitivity. (2022).

Two dominant timescales of cytoskeletal crosslinking in the viscoelastic response of the cytoplasm. (2022).

Tau inhibits the long-range dynein-mediated motility of early phagosomes. (2022).

Suspension Vero cell culture technology for high titer production of viral vaccines. (2022).

Structural determinants of yeast protein-protein interaction interface evolution at the residue level. (2022).

Sizing up the challenge: The number of active dynein teams scales with organelle size. (2022).

"Recent advancement in electrode materials and fabrication, microfluidic designs, and self-powered systems for wearable non-invasive electrochemical glucose monitoring". (2022).

Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models. (2022).

Protein-Mediated Aqueous Synthesis of Stable Methylammonium Lead Bromide Perovskite Nanocrystals: Implications for Biological and Environmental Applications. (2022).

"Prostate cancer cells of increasing metastatic potential exhibit diverse contractile forces, cell stiffness, and motility in a microenvironment stiffness-dependent manner". (2022).

Overview of recent advances in Vero cells genomic characterization and engineering for high-throughput vaccine manufacturing. (2022).

Optimization of rAd5 vectored Newcastle vaccine production in HEK293 at high cell densities. (2022).

"Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX". (2022).

Nanoplasmonic amplification in microfluidics enables minute-scale colorimetric quantification of nucleic acid biomarkers (preprint). (2022).

Multivalent Influenza vaccine production in HEK-293 cells in response to pandemic threats. (2022).

Monitoring the Recombinant Adeno-Associated Virus Production using Extended Kalman Filter. (2022).

Modelling vaccination strategies for COVID-19. (2022).

Modeling the carbon-dioxide response function in fMRI under task and resting-state conditions. (2022).

Mineral tessellation in bone and the stenciling principle for extracellular matrix mineralization. (2022).

Mapping of trabecular bone anisotropy and volume fraction in 3D using ?CT images of the human calcaneus. (2022).

Manufacturing of seasonal and pandemic influenza vaccines–A case study. (2022).

Intensified virus production in suspension HEK293SF cells using high inoculum fed-batch or low-perfusion rate cultures with continuous harvest. (2022).

Intensification of influenza virus production in fed-batch and perfusion cultures of HEK293SF cells. (2022).

Integrating hybrid spatiotemporal models and multiscale data for the study of cancer progression in 3D cultures. (2022).

Huntingtin S421 phosphorylation and expression levels differentially affect signalling and degradative intracellular cargoes. (2022).

Highly Concentrated Nitrogen? Doped Carbon Nanotubes in Alginate–Gelatin 3D Hydrogels Enable in Vitro Breast Cancer Spheroid Formation. (2022).

GTPase-Dependent Mechanointegration of Shear-Mediated Cell Contractility Through Dynamic Binding of FLNa and FilGAP. (2022).

Fungal Intelligence: Space Search by Filamentous Fungi. (2022).

Fabrication and Characterization of Autonomously Self?Healable and Stretchable Soft Microfluidics. (2022).

Do commonly-used dynamic Functional Connectivity Assessment methods produce comparable results? (2022).

Development of scalable downstream processing platform for HEK293SF cell-based influenza vaccine production. (2022).

Design and production of vaccines against COVID-19 using established vaccine platforms. (2022).

"Corrigendum to"" Mineral tessellation in bone and the stenciling principle for extracellular matrix mineralization""[J. Struct. Biol. 214 (1)(2022) 107823]". (2022).

"Complementary Metal-Oxide-Semiconductor-Based Sensing Platform for Trapping, Imaging, and Chemical Characterization of Biological Samples". (2022).

Bringing language to dynamic brain states: the default network dominates neural responses to evolving movie stories. (2022).

Bioprocessing of viral vaccines––Introduction. (2022).

Bioprocessing of Viral Vaccines. (2022).

Bioprinting An In Vitro Head And Neck Cancer Co-Culture Using A Decellularized Extracellular Matrix Bioink. (2022).

An adenovirus-based vaccine manufacturing technology platform for mucosal or parenteral immunization against poultry diseases in sub-Saharan Africa. (2022).

 

2021

Yan, X., Mitsis, G. D. & Boudrias, M. H. Identification of Beta Oscillatory Patterns During a Hand Grip Motor Task: A Comparative Analysis pre- and post-Exercise. Annu Int Conf IEEE Eng Med Biol Soc 2021, 993-996 (2021). https://doi.org:10.1109/EMBC46164.2021.9629631

Y Chehrehsaz, K. H., A Hadjizadeh, L Moradi, S Mahshid. in Metals and Materials International (2021).

Xifra-Porxas, A., Kassinopoulos, M. & Mitsis, G. D. Physiological and motion signatures in static and time-varying functional connectivity and their subject identifiability. Elife 10 (2021). https://doi.org:10.7554/eLife.62324

Xifra-Porxas, A., Ghosh, A., Mitsis, G. D. & Boudrias, M. H. Estimating brain age from structural MRI and MEG data: Insights from dimensionality reduction techniques. Neuroimage 231, 117822 (2021). https://doi.org:10.1016/j.neuroimage.2021.117822

Wagner, C. E. et al. Vaccine nationalism and the dynamics and control of SARS-CoV-2. Science 373, eabj7364 (2021). https://doi.org:10.1126/science.abj7364

Wagner, C. Vaccine breakthrough and the invasion dynamics of SARS-CoV-2 variants. medRxiv (2021).

Wagner, C. Leveraging large-deviation statistics to decipher the stochastic properties of measured trajectories. New Journal of Physics 23, 1 (2021).

Wagner, C. Flows and Networks in Global Innovation System among Top R&D Nations. (2021).

van Delft, F. C. M. J. M. et al. Design and fabrication of networks for bacterial computing. New Journal of Physics 23 (2021). https://doi.org:10.1088/1367-2630/ac1d38

V de Buffrénil, A. Q. Bone tissue types: A brief account of currently used categories. Vertebrate skeletal histology and paleohistology (2021). https://doi.org:10.1201/9781351189590-8

Tokarova, V. et al. Patterns of bacterial motility in microfluidics-confining environments. Proc Natl Acad Sci U S A 118 (2021). https://doi.org:10.1073/pnas.2013925118

Tirgar, P. et al. Toward embryo cryopreservation-on-a-chip: A standalone microfluidic platform for gradual loading of cryoprotectants to minimize cryoinjuries. Biomicrofluidics 15, 034104 (2021). https://doi.org:10.1063/5.0047185

T., K. i. S. M. S. A. N. D. V. N. in 2021 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2021 (2021).

Sudalaiyadum Perumal, A. et al. As good as it gets: a scaling comparison of DNA computing, network biocomputing, and electronic computing approaches to an NP-complete problem. New Journal of Physics 23 (2021). https://doi.org:10.1088/1367-2630/ac3883

Srivastava, L. K., Ju, Z., Ghagre, A. & Ehrlicher, A. J. Spatial distribution of lamin A/C determines nuclear stiffness and stress-mediated deformation. J Cell Sci 134 (2021). https://doi.org:10.1242/jcs.248559

Sharir-Ivry, A. & Xia, Y. Quantifying evolutionary importance of protein sites: A Tale of two measures. PLoS Genet 17, e1009476 (2021). https://doi.org:10.1371/journal.pgen.1009476

Sene, M. A. et al. Haplotype-resolved de novo assembly of the Vero cell line genome. NPJ Vaccines 6, 106 (2021). https://doi.org:10.1038/s41541-021-00358-9

Sène, M.-A., Xia, Y. & Kamen, A. A. Comparative Transcriptomics Analyses of a Vero Cell Line in Suspension Versus Adherent Culture Conditions. (2021). https://doi.org:10.21203/rs.3.rs-1014921/v1

SC Tetlalmatzi, A. H., G Brouhard. DCX Uses Distinct Domains to Sequentially Nucleate and Stabilize Microtubules. Biophysical Journal 120, 258 (2021).

Sanati, A. et al. Gold Nano/Micro-Islands Overcome the Molecularly Imprinted Polymer Limitations to Achieve Ultrasensitive Protein Detection. ACS Sens 6, 797-807 (2021). https://doi.org:10.1021/acssensors.0c01701

Saad-Roy, C. M. et al. Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes. Science 372, 363-370 (2021). https://doi.org:10.1126/science.abg8663

Saad-Roy, C. M. et al. Partial immunity and SARS-CoV-2 mutations-Response. Science 372, 354-355 (2021). https://doi.org:10.1126/science.abi6719

S Nithianantham, M. I., I Gaska, H Pandey, T Bodrug, S Inagaki, ... The mechanochemical origins of the microtubule sliding motility within the kinesin-5 domain organization. bioRxiv (2021). https://doi.org:10. 12.463902

R Carney, T. R., H Koster, HJ O'Toole, S Wachsmann-Hogiu. Surface enhanced Raman scattering (SERS) nanoparticles for rapid chemical analysis of tumor-associated extracellular vesicles (EVs). Colloidal Nanoparticles for Biomedical Applications XVI 11659, 116590H (2021).

Ort, C., Chen, Y., Ghagre, A., Ehrlicher, A. & Moraes, C. Bioprintable, Stiffness-Tunable Collagen-Alginate Microgels for Increased Throughput 3D Cell Culture Studies. ACS Biomater Sci Eng 7, 2814-2822 (2021). https://doi.org:10.1021/acsbiomaterials.1c00129

Ng, S. L., Rowland, P. & Kinsella, E. A. Emancipatory knowledge and epistemic reflexivity: The knowledge and practice for change? Med Educ 55, 8-10 (2021). https://doi.org:10.1111/medu.14414

Minh, A. D. & Kamen, A. A. Critical Assessment of Purification and Analytical Technologies for Enveloped Viral Vector and Vaccine Processing and Their Current Limitations in Resolving Co-Expressed Extracellular Vesicles. Vaccines (Basel) 9 (2021). https://doi.org:10.3390/vaccines9080823

MH Nia, S. A., JG Munguia-Lopez, JM Kinsella, TGM van de Ven. pH-responsive polymer-based biomacromolecule nanosponges as biodegradable carriers for DOX delivery. (2021).

Mahshid, S. S., Flynn, S. E. & Mahshid, S. The potential application of electrochemical biosensors in the COVID-19 pandemic: A perspective on the rapid diagnostics of SARS-CoV-2. Biosens Bioelectron 176, 112905 (2021). https://doi.org:10.1016/j.bios.2020.112905

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M Jalali, Z. G., Y Yu, RS Moakhar, Y Ding, M Zhuang, N Zhou, T König, ... Synergistic enhancement of photoluminesent intensity in monolayer molybdenum disulfide embedded with plasmonic nanostructures for catalytic sensing. (2021).

LP Bergeron-Sandoval, S. K., HK Heris, CLA Chang, CE Cornell, ... Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling. Proceedings of the National Academy of Sciences 118, e2113789118 (2021).

Liu, J., Siavash Moakhar, R., Mahshid, S., Vasefi, F. & Wachsmann-Hogiu, S. Multimodal electrochemical and SERS platform for chlorfenapyr detection. Applied Surface Science 566 (2021). https://doi.org:10.1016/j.apsusc.2021.150617

Lin, Z., Jiang, T., Kinsella, J. M., Shang, J. & Luo, Z. Assessing roughness of extrusion printed soft materials using a semi-quantitative method. Materials Letters 303 (2021). https://doi.org:10.1016/j.matlet.2021.130480

Kort-Mascort, J. et al. Decellularized Extracellular Matrix Composite Hydrogel Bioinks for the Development of 3D Bioprinted Head and Neck in Vitro Tumor Models. ACS Biomater Sci Eng 7, 5288-5300 (2021). https://doi.org:10.1021/acsbiomaterials.1c00812

Klionsky, D. J. et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1). Autophagy 17, 1-382 (2021). https://doi.org:10.1080/15548627.2020.1797280

Kiesslich, S., Kim, G. N., Shen, C. F., Kang, C. Y. & Kamen, A. A. Bioreactor production of rVSV-based vectors in Vero cell suspension cultures. Biotechnol Bioeng 118, 2649-2659 (2021). https://doi.org:10.1002/bit.27785

Kassinopoulos, M. & Mitsis, G. D. Physiological noise modeling in fMRI based on the pulsatile component of photoplethysmograph. Neuroimage 242, 118467 (2021). https://doi.org:10.1016/j.neuroimage.2021.118467

Kamen, A. A. Vectored-Vaccine Platforms Enabled Rapid Development of Safe and Effective Vaccines in Response to COVID-19 Pandemic Situation. Vaccines (Basel) 9 (2021). https://doi.org:10.3390/vaccines9070722

Joshi, P. R. H., Venereo-Sanchez, A., Chahal, P. S. & Kamen, A. A. Advancements in molecular design and bioprocessing of recombinant adeno-associated virus gene delivery vectors using the insect-cell baculovirus expression platform. Biotechnol J 16, e2000021 (2021). https://doi.org:10.1002/biot.202000021

Joshi, P. R. H. et al. Development of a scalable and robust AEX method for enriched rAAV preparations in genome-containing VCs of serotypes 5, 6, 8, and 9. Mol Ther Methods Clin Dev 21, 341-356 (2021). https://doi.org:10.1016/j.omtm.2021.03.016

Joshi, P. R. H., Bernier, A., Chahal, P. S. & Kamen, A. Development and Validation of an Anion Exchange High-Performance Liquid Chromatography Method for Analysis of Empty Capsids and Capsids Encapsidating Genetic Material in a Purified Preparation of Recombinant Adeno-Associated Virus Serotype 5. Hum Gene Ther 32, 1390-1402 (2021). https://doi.org:10.1089/hum.2020.317

Jenkins, K., Kinsella, E. A. & DeLuca, S. Being and becoming a nurse: Toward an ontological and reflexive turn in first-year nursing education. Nurs Inq 28, e12420 (2021). https://doi.org:10.1111/nin.12420

JC Iglesias, V. M., A Venereo-Sanchez, X Xu, J Robitaille, R Voyer. in Journal of Physics: Conference Series (2021).

Janska, P. et al. Effect of physicochemical parameters on the stability and activity of garlic alliinase and its use for in-situ allicin synthesis. PLoS One 16, e0248878 (2021). https://doi.org:10.1371/journal.pone.0248878

Jalali, M. et al. in 2021 IEEE 21st International Conference on Nanotechnology (NANO) 400-402 (2021).

Jalali, M. et al. Plasmonic nanobowtiefluidic device for sensitive detection of glioma extracellular vesicles by Raman spectrometry. Lab Chip 21, 855-866 (2021). https://doi.org:10.1039/d0lc00957a

Imanbekova, M. et al. Identification of amyloid beta in small extracellular vesicles via Raman spectroscopy. Nanoscale Adv 3, 4119-4132 (2021). https://doi.org:10.1039/d1na00330e

Hosseini, II et al. Nanofluidics for Simultaneous Size and Charge Profiling of Extracellular Vesicles. Nano Lett 21, 4895-4902 (2021). https://doi.org:10.1021/acs.nanolett.0c02558

Heidari Nia, M. et al. Biotemplated Hollow Mesoporous Silica Particles as Efficient Carriers for Drug Delivery. ACS Appl Bio Mater 4, 4201-4214 (2021). https://doi.org:10.1021/acsabm.0c01671

Gonzalez-Dominguez, I. et al. A Four-Step Purification Process for Gag VLPs: From Culture Supernatant to High-Purity Lyophilized Particles. Vaccines (Basel) 9 (2021). https://doi.org:10.3390/vaccines9101154

Ghagre, A. et al. Pattern-Based Contractility Screening, a Reference-Free Alternative to Traction Force Microscopy Methodology. ACS Appl Mater Interfaces 13, 19726-19735 (2021). https://doi.org:10.1021/acsami.1c02987

Ghadie, M. & Xia, Y. Mutation Edgotype Drives Fitness Effect in Human. Front Bioinform 1, 690769 (2021). https://doi.org:10.3389/fbinf.2021.690769

Fulber, J. P. C. et al. Process Development for Newcastle Disease Virus-Vectored Vaccines in Serum-Free Vero Cell Suspension Cultures. Vaccines (Basel) 9 (2021). https://doi.org:10.3390/vaccines9111335

Flores-Torres, S. et al. Alginate-gelatin-Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models. Biofabrication 13 (2021). https://doi.org:10.1088/1758-5090/abdb87

Ezra, M., Garry, P., Rowland, M. J., Mitsis, G. D. & Pattinson, K. T. Phase dynamics of cerebral blood flow in subarachnoid haemorrhage in response to sodium nitrite infusion. Nitric Oxide 106, 55-65 (2021). https://doi.org:10.1016/j.niox.2020.10.004

E Arts, A. B., J Pedersen, MA Lafrance, J Knapp, H Azizi, Y Li, . A VSV-based HIV-1 vaccine provides protection in macaques against low dose cross-clade SHIVenv_SF162_P3 challenge. Journal of the International AIDS Society 24, 31-32 (2021).

Do Minh, A. et al. Characterization of Extracellular Vesicles Secreted in Lentiviral Producing HEK293SF Cell Cultures. Viruses 13 (2021). https://doi.org:10.3390/v13050797

Djaileb, A. et al. Cross-validation of ELISA and a portable surface plasmon resonance instrument for IgG antibody serology with SARS-CoV-2 positive individuals. Analyst 146, 4905-4917 (2021). https://doi.org:10.1039/d1an00893e

Del Real Mata, C., Siavash Moakhar, R., Hosseini, II, Jalali, M. & Mahshid, S. A nanostructured microfluidic device for plasmon-assisted electrochemical detection of hydrogen peroxide released from cancer cells. Nanoscale 13, 14316-14329 (2021). https://doi.org:10.1039/d0nr07608b

D Fixler, E. G., S Wachsmann-Hogiu. (Proc. of SPIE Vol 11976, 1197601-1, 2021).

D Beaudet, A. C., CL Berger, AG Hendricks. Cargo-Specific Regulation of Transport by TAU. Biophysical Journal (2021).

Chen, Y. F. & Xia, Y. Structural Profiling of Bacterial Effectors Reveals Enrichment of Host-Interacting Domains and Motifs. Front Mol Biosci 8, 626600 (2021). https://doi.org:10.3389/fmolb.2021.626600

Chang, H. Y. et al. A Practical Guide to Metabolomics Software Development. Anal Chem 93, 1912-1923 (2021). https://doi.org:10.1021/acs.analchem.0c03581

CAT Silva, A. K., O Henry. Recent advances and current challenges in process intensification of cell culture?based influenza virus vaccine manufacturing. The Canadian Journal of Chemical Engineering 99, 2525-2535 (2021).

Cario, A. et al. Novel Effect of Tau N-Terminal Mutation, R5L, on Microtubule Mediated Condensation. Biophysical Journal 120, 257a-258a (2021). https://doi.org:10.1016/j.bpj.2020.11.1661

C Webb, J. J. Laser applications in biology and biotechnology. Handb Laser Technol Appl: Laser Appl: Med Metrol Commun (2021).

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Bevacqua, A., Bakshi, S. & Xia, Y. Principal component analysis of alpha-helix deformations in transmembrane proteins. PLoS One 16, e0257318 (2021). https://doi.org:10.1371/journal.pone.0257318

Bergeron-Sandoval, L. P. et al. Endocytic proteins with prion-like domains form viscoelastic condensates that enable membrane remodeling. Proc Natl Acad Sci U S A 118 (2021). https://doi.org:10.1073/pnas.2113789118

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Baker, R. E., Park, S. W., Wagner, C. E. & Metcalf, C. J. E. The limits of SARS-CoV-2 predictability. Nat Ecol Evol 5, 1052-1054 (2021). https://doi.org:10.1038/s41559-021-01514-z

B., K. J. P. A. S. K. I. C. R. W. S. S. C. M. A. O. D.-H. B. Synthesis of nanomaterials for biofuel and bioenergy applications. Nanomaterials: Application in Biofuels and Bioenergy Production Systems (2021).

Amini, A., Khavari, A., Barthelat, F. & Ehrlicher, A. J. Centrifugation and index matching yield a strong and transparent bioinspired nacreous composite. Science 373, 1229-1234 (2021). https://doi.org:10.1126/science.abf0277

Alsheghri, A. et al. Optimization of 3D network topology for bioinspired design of stiff and lightweight bone-like structures. Mater Sci Eng C Mater Biol Appl 123, 112010 (2021). https://doi.org:10.1016/j.msec.2021.112010

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2020

Zhang, Y., Pham, H. M., Munguia-Lopez, J. G., Kinsella, J. M. & Tran, S. D. The Optimization of a Novel Hydrogel-Egg White-Alginate for 2.5D Tissue Engineering of Salivary Spheroid-Like Structure. Molecules 25 (2020). https://doi.org:10.3390/molecules25235751

Yan, X., Boudrias, M. H. & Mitsis, G. D. Artifact Removal in tACS-EEG Recordings: A Combined Methodology Based on the Empirical Wavelet Transform. Annu Int Conf IEEE Eng Med Biol Soc 2020, 944-947 (2020). https://doi.org:10.1109/EMBC44109.2020.9176488

Xia, C. H. et al. Multi-scale network regression for brain-phenotype associations. Hum Brain Mapp 41, 2553-2566 (2020). https://doi.org:10.1002/hbm.24982

Wang, H. T. et al. Finding the needle in a high-dimensional haystack: Canonical correlation analysis for neuroscientists. Neuroimage 216, 116745 (2020). https://doi.org:10.1016/j.neuroimage.2020.116745

Wagner, C. E. et al. Economic and Behavioral Influencers of Vaccination and Antimicrobial Use. Front Public Health 8, 614113 (2020). https://doi.org:10.3389/fpubh.2020.614113

Wagner, C. E. et al. Climatological, virological and sociological drivers of current and projected dengue fever outbreak dynamics in Sri Lanka. J R Soc Interface 17, 20200075 (2020). https://doi.org:10.1098/rsif.2020.0075

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Wachsmann-Hogiu, M. I. A. S. P. S. K. S. in SPIE - The International Society of Optics and Photonics (2020).

Transfiguracion, J. et al. Rapid In-Process Monitoring of Lentiviral Vector Particles by High-Performance Liquid Chromatography. Mol Ther Methods Clin Dev 18, 803-810 (2020). https://doi.org:10.1016/j.omtm.2020.08.005

Tavakolian, M. et al. Highly Absorbent Antibacterial and Biofilm-Disrupting Hydrogels from Cellulose for Wound Dressing Applications. ACS Appl Mater Interfaces 12, 39991-40001 (2020). https://doi.org:10.1021/acsami.0c08784

T Hofmann, G. L., S Ghoshal, N Tufenkji, D Brambilla, JR Dutcher, ... Technology readiness and overcoming barriers to sustainably implement nanotechnology-enabled plant agriculture. Nature Food 1, 416-425 (2020).

Suarasan, S. et al. Superhydrophobic bowl-like SERS substrates patterned from CMOS sensors for extracellular vesicle characterization. J Mater Chem B 8, 8845-8852 (2020). https://doi.org:10.1039/d0tb00889c

Siavash Moakhar, R. et al. A Nanostructured Gold/Graphene Microfluidic Device for Direct and Plasmonic-Assisted Impedimetric Detection of Bacteria. ACS Appl Mater Interfaces 12, 23298-23310 (2020). https://doi.org:10.1021/acsami.0c02654

Sharon, D. M. et al. A pooled genome-wide screening strategy to identify and rank influenza host restriction factors in cell-based vaccine production platforms. Sci Rep 10, 12166 (2020). https://doi.org:10.1038/s41598-020-68934-y

Savva, A. D., Kassinopoulos, M., Smyrnis, N., Matsopoulos, G. K. & Mitsis, G. D. Effects of motion related outliers in dynamic functional connectivity using the sliding window method. J Neurosci Methods 330, 108519 (2020). https://doi.org:10.1016/j.jneumeth.2019.108519

Sanati, A. et al. Deposition of Gold Nano-Micro Islands on Electrochemically Reduced Graphene Oxide to Use in Combination with Molecularly Imprinted Polymers. ECS Meeting Abstracts MA2020-01, 2471-2471 (2020). https://doi.org:10.1149/MA2020-01352471mtgabs

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Rostami, A., Hadjizadeh, A. & Mahshid, S. Colorimetric determination of dopamine using an electrospun nanofibrous membrane decorated with gold nanoparticles. Journal of Materials Science 55, 7969-7980 (2020). https://doi.org:10.1007/s10853-020-04547-0

Rojalin, T. et al. Hybrid Nanoplasmonic Porous Biomaterial Scaffold for Liquid Biopsy Diagnostics Using Extracellular Vesicles. ACS Sens 5, 2820-2833 (2020). https://doi.org:10.1021/acssensors.0c00953

Reznikov, N. et al. Biological stenciling of mineralization in the skeleton: Local enzymatic removal of inhibitors in the extracellular matrix. Bone 138, 115447 (2020). https://doi.org:10.1016/j.bone.2020.115447

Reznikov, N., Buss, D. J., Provencher, B., McKee, M. D. & Piche, N. Deep learning for 3D imaging and image analysis in biomineralization research. J Struct Biol 212, 107598 (2020). https://doi.org:10.1016/j.jsb.2020.107598

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Reznikov, N. et al. Altered topological blueprint of trabecular bone associates with skeletal pathology in humans. Bone Rep 12, 100264 (2020). https://doi.org:10.1016/j.bonr.2020.100264

Ram-Mohan, S. et al. Tissue traction microscopy to quantify muscle contraction within precision-cut lung slices. Am J Physiol Lung Cell Mol Physiol 318, L323-L330 (2020). https://doi.org:10.1152/ajplung.00297.2019

Patmanidis, S. et al. Individualized growth prediction of mice skin tumors with maximum likelihood estimators. Comput Methods Programs Biomed 185, 105165 (2020). https://doi.org:10.1016/j.cmpb.2019.105165

P Joshi, A. V.-S., P Chahal, A Kamen. Advancements in Insect-Cell Baculovirus Expression Vector Platform for Production of Recombinant Adeno-Associated Virus-Based Gene Delivery Vectors. Authorea Preprints (2020).

Nicolau, D. V. & Bafadhel, M. Inhaled corticosteroids in virus pandemics: a treatment for COVID-19? Lancet Respir Med 8, 846-847 (2020). https://doi.org:10.1016/S2213-2600(20)30314-3

Naseri, S., Koushki, N., Rezabeigi, E., Ehrlicher, A. & Nazhat, S. N. A nondestructive contactless technique to assess the viscoelasticity of blood clots in real-time. J Mech Behav Biomed Mater 110, 103921 (2020). https://doi.org:10.1016/j.jmbbm.2020.103921

Moco, P. D., Aharony, N. & Kamen, A. Adeno-Associated Viral Vectors for Homology-Directed Generation of CAR-T Cells. Biotechnol J 15, e1900286 (2020). https://doi.org:10.1002/biot.201900286

Mitsis, G. D. et al. Functional brain networks of patients with epilepsy exhibit pronounced multiscale periodicities, which correlate with seizure onset. Hum Brain Mapp 41, 2059-2076 (2020). https://doi.org:10.1002/hbm.24930

Mann-Krzisnik, D. W. & Mitsis, G. D. Modeling BOLD-fMRI Hemodynamics via Multidimensional Decomposition of Electrophysiology Data: A Simulation Study. Annu Int Conf IEEE Eng Med Biol Soc 2020, 398-401 (2020). https://doi.org:10.1109/EMBC44109.2020.9175469

Mangion, M. et al. Evaluation of novel HIV vaccine candidates using recombinant vesicular stomatitis virus vector produced in serum-free Vero cell cultures. Vaccine 38, 7949-7955 (2020). https://doi.org:10.1016/j.vaccine.2020.10.058

Mahshid, S. in Electrochemical Society Meeting Abstracts Vol. 237 (2020).

Luck, K. et al. A reference map of the human binary protein interactome. Nature 580, 402-408 (2020). https://doi.org:10.1038/s41586-020-2188-x

Liu, J. et al. An AgNP-deposited commercial electrochemistry test strip as a platform for urea detection. Sci Rep 10, 9527 (2020). https://doi.org:10.1038/s41598-020-66422-x

Liu, J., Jalali, M., Mahshid, S. & Wachsmann-Hogiu, S. Are plasmonic optical biosensors ready for use in point-of-need applications? Analyst 145, 364-384 (2020). https://doi.org:10.1039/c9an02149c

Kim, S. H. et al. Review on Stress Tolerance in Campylobacter jejuni. Front Cell Infect Microbiol 10, 596570 (2020). https://doi.org:10.3389/fcimb.2020.596570

Kiesslich, S., Vila-Cha Losa, J. P., Gelinas, J. F. & Kamen, A. A. Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X hydro fixed-bed. J Biotechnol 310, 32-39 (2020). https://doi.org:10.1016/j.jbiotec.2020.01.015

Kiesslich, S. & Kamen, A. A. Vero cell upstream bioprocess development for the production of viral vectors and vaccines. Biotechnol Adv 44, 107608 (2020). https://doi.org:10.1016/j.biotechadv.2020.107608

Jalali, M. et al. Hydrothermal Growth of Molybdenum Disulfide Composited with Electrodeposited Gold and Its Photoelectrochemical Properties. ECS Meeting Abstracts MA2020-01, 2156-2156 (2020). https://doi.org:10.1149/MA2020-01282156mtgabs

Jalali, M. et al. Nanopattern-Assisted Direct Growth of Peony-like 3D MoS(2)/Au Composite for Nonenzymatic Photoelectrochemical Sensing. ACS Appl Mater Interfaces 12, 7411-7422 (2020). https://doi.org:10.1021/acsami.9b17449

Jalali, M., Filine, E., Dalfen, S. & Mahshid, S. Microscale reactor embedded with Graphene/hierarchical gold nanostructures for electrochemical sensing: application to the determination of dopamine. Mikrochim Acta 187, 90 (2020). https://doi.org:10.1007/s00604-019-4059-4

Imanbekova, M., Perumal, A. S., Kheireddine, S., Nicolau, D. V. & Wachsmann-Hogiu, S. Lensless, reflection-based dark-field microscopy (RDFM) on a CMOS chip. Biomed Opt Express 11, 4942-4959 (2020). https://doi.org:10.1364/BOE.394615

Hosseini, I. I., Liu, Z., Reisner, W. & Mahshid, S. in 2020 IEEE 20th International Conference on Nanotechnology (IEEE-NANO) 246-249 (2020).

Hooshyar, M. et al. Cyclic epidemics and extreme outbreaks induced by hydro-climatic variability and memory. J R Soc Interface 17, 20200521 (2020). https://doi.org:10.1098/rsif.2020.0521

Hansen, N. L. et al. Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol. Microb Cell Fact 19, 15 (2020). https://doi.org:10.1186/s12934-020-1284-9

H. Sadreazami, G. M. in 2020 18th IEEE International New Circuits and Systems Conference (NEWCAS) (2020).

Gelinas, J. F., Kiesslich, S., Gilbert, R. & Kamen, A. A. Titration methods for rVSV-based vaccine manufacturing. MethodsX 7, 100806 (2020). https://doi.org:10.1016/j.mex.2020.100806

Fixler, D., Goldys, E. M. & Wachsmann-Hogiu, S. in PROGRESS IN BIOMEDICAL OPTICS AND IMAGING (2020).

FC van Delft1a, G. I., DV Nicolau Jr, AS Perumal, O Kašpar, ... Engineering Challenges and Future Road-map of Network Computing. INFORMATION STORAGE AND PROCESSING IN BIOLOGICAL SYSTEMS, 17 (2020).

Farnos, O. et al. Rapid High-Yield Production of Functional SARS-CoV-2 Receptor Binding Domain by Viral and Non-Viral Transient Expression for Pre-Clinical Evaluation. Vaccines (Basel) 8 (2020). https://doi.org:10.3390/vaccines8040654

Farnos, O. et al. Establishing a Robust Manufacturing Platform for Recombinant Veterinary Vaccines: An Adenovirus-Vector Vaccine to Control Newcastle Disease Virus Infections of Poultry in Sub-Saharan Africa. Vaccines (Basel) 8 (2020). https://doi.org:10.3390/vaccines8020338

Elting, J. W. et al. Assessment of dynamic cerebral autoregulation in humans: Is reproducibility dependent on blood pressure variability? PLoS One 15, e0227651 (2020). https://doi.org:10.1371/journal.pone.0227651

Dusseaux, S., Wajn, W. T., Liu, Y., Ignea, C. & Kampranis, S. C. Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids. Proc Natl Acad Sci U S A 117, 31789-31799 (2020). https://doi.org:10.1073/pnas.2013968117

Do Minh, A., Tran, M. Y. & Kamen, A. A. Lentiviral Vector Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells. Methods Mol Biol 2086, 77-83 (2020). https://doi.org:10.1007/978-1-0716-0146-4_6

del Real Mata, C., Siavash Moakhar, R. & Mahshid, S. A Nanostructured Electrode for Photoelectrochemical Detection of Hydrogen Peroxide. ECS Meeting Abstracts MA2020-01, 2189-2189 (2020). https://doi.org:10.1149/MA2020-01282189mtgabs

D.V., N. in IEEE Transactions on Nanobioscience (2020).

Chaubet, L., Khadivi Heris, H., Ehrlicher, A. J. & Hendricks, A. G. Dynamic Crosslinking of the Actin Cytoskeleton Governs Cell Mechanics. Biophysical Journal 118, 280a-281a (2020). https://doi.org:10.1016/j.bpj.2019.11.1603

Chaubet, L., Chaudhary, A. R., Heris, H. K., Ehrlicher, A. J. & Hendricks, A. G. Dynamic actin cross-linking governs the cytoplasm's transition to fluid-like behavior. Mol Biol Cell 31, 1744-1752 (2020). https://doi.org:10.1091/mbc.E19-09-0504

C Webb, J. J. in CRC Press (2020).

Buss, D. J., Reznikov, N. & McKee, M. D. Crossfibrillar mineral tessellation in normal and Hyp mouse bone as revealed by 3D FIB-SEM microscopy. J Struct Biol 212, 107603 (2020). https://doi.org:10.1016/j.jsb.2020.107603

Botvinik-Nezer, R. et al. Variability in the analysis of a single neuroimaging dataset by many teams. Nature 582, 84-88 (2020). https://doi.org:10.1038/s41586-020-2314-9

Benslimane, Y. et al. Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells. Mol Cell 79, 846-856 e848 (2020). https://doi.org:10.1016/j.molcel.2020.07.010

Bao, G. et al. Triggered micropore-forming bioprinting of porous viscoelastic hydrogels. Mater Horiz 7, 2336-2347 (2020). https://doi.org:10.1039/d0mh00813c

Athanasiadou, D. et al. Nanostructure of mouse otoconia. J Struct Biol 210, 107489 (2020). https://doi.org:10.1016/j.jsb.2020.107489

 

2019

Jiang, T., Munguia-Lopez, J., Gu, K., Bavoux, M., Flores-Torres, S., Kort-Mascort, J., Grant, J., Vijayakumar, S., De Leon-Rodriguez, A., Ehrlicher, A.J., and Kinsella, J.M. Engineering bioprintable alginate/gelatin composite hydrogels with tunable mechanical and cell adhesive properties to modulate tumor spheroid growth kinetics. IOP Science. 2019; 12 (1), https://doi.org/10.1088/1758-5090/ab3a5c

Jiang, T., Munguia-Lopez, J., Flores-Torres, S., Kort-Mascort, J., and Kinsella, J.M. Extrusion bioprinting of soft materials: An emerging technique for biological model fabrication. Applied Physics Review. 2019.

Tao, O., Kort-Mascort, J., Lin, Y. Pham, H.M., Charbonneau, A.M., ElKashty, O.A., Kinsella, J.M., and Tran, S.D. The Applications of 3D Printing for Craniofacial Tissue Engineering. MDPI. 2019. 10(7), 480; https://doi.org/10.3390/mi10070480

Botvinik-Nezer, R., Holzmeister, F., Camerer, C.F., Dreber, A., Huber, J., Johannesson, M., Kirchler, M., Iwanir, R., Mumford, J.A., Adcock, R.A., Avesani, P., Baczkowski, B.M., Bajracharya, A., Bakst, L., Ball, S., Barilari, M., Bault, N., Beaton, D., Beitner, J., Benoit, R.G., Berkers, R.M.W.J. Bhanji, J.P., Biswal, B.B., Bobadilla-Suarez, S., Bortolini, T., Bottenhorn, K.L., Bowring, A., Braem, S., Brooks, H.R., Brudner, E.G., Calderon, C.B., Camilleri, J.A., Castrellon, J.J., Cecchetti, L., Cieslik, E.C., Cole, Z.J., Collignon, O., Cox, R.W., Cunningham, W.A., Czoschke, S., Dadi, K., Davis, C.P., De Luca, A., Delgado, M.R., Demetriou, L., Dennison, J.B., Di, X., Dickie, E.W., Dobryakova, E., Donnat, C.L., Dukart, J., Duncan, N.W., Durnez, J., Eed, A., Eickhoff, S.B., Erhart, A., Fontanesi, L., Fricke, G.M., Fu, S., Galvan, A., Gau, R., Genon, S., Glatard, T., Glerean, E., Goeman, J.J., A. E. Golowin, S.A.E., Gonzalez-Garcia, C., Gorgolewski, K.J., Grady, C.L., Green, M.A., Guassi Moreira, J.F., Guest, O., Hakimi, S., Hamilton, J.P., Hancock, R., Handjaras, G., Harry, B.B., Hawco, C., Herholz, P., Herman, G., Heunis, S., Hoffstaedter, F., Hogeveen, J., Holmes, S., Hu, C.P., Huettel, S.A., Hughes, M.E., Iacovella, V., Iordan, A.D., M. Isager, P.M., Isik, A.I. Jahn, A., Johnson, M.R., Johnstone, T., Joseph, M.J.E., Juliano, A.C., Kable, J.W., Kassinopoulos, M., Koba, C., Kong, X.Z., Koscik, T.R., Erkut Kucukboyaci, N., Kuhl, B.A., Kupek, S., Laird, A.R., Lamm, C., Langner, R., Lauharatanahirun, N., Lee, H., Lee, S., Leemans, A., Leo, A., Lesage, E., Li, F., Li, M.Y.C., Lim, P.C., Lintz, E.N., Liphardt, S.W., Losecaat Vermeer, A.B., Love, B.C., Mack, M.L., Malpica, N., Marins, T., Maumet, C., McDonald, K., McGuire, J.T., Melero, H., Mendez Leal, A.S., Meyer, B.,Meyer, K.N., Mihai, G., Mitsis, G.D., Moll, J., Nielson, D.M., Nilsonne, G., Notter, M.P., Olivetti, E., Onicas, A.I., Papale, P., Patil, K.R., Peelle, J.E., Perez, A., Pischedda, D.,  Poline, J.B., Prystauka, Y., Ray, S., Reuter-Lorenz, P.A., Reynolds, R.C., Ricciardi, E., Rieck, J.R., Rodriguez-Thompson, A.M., Romyn, A., Salo, T., Samanez-Larkin, G.R., Sanz-Morales, E., Schlichting, M.L, Schultz, D.H., Shen, Q., Sheridan, M.A, Silvers, J.A., Skagerlund, K., Smith, A., David V. Smith, D.V., Peter Sokol-Hessner, P., Steinkamp, S.R., Tashjian, S.M., Thirion, B., Thorp, J.N., Tinghog, G., Tisdall, L., Tompson, S.H., Claudio Toro-Serey, C., Torre Tresols, J.J., Tozzi, L., Truong, V., Luca Turella, L., van 't Veer, A.E., Verguts, T., Vettel, J.M., Vijayarajah, S., Vo, K., Wall, M.B., Weeda, W.D., Weis, S., White, D.J., Wisniewski, D., Xifra-Porxas, A., Yearling, E.A., Yoon, S., Yuan, R., Yuen, K.S.L, Zhang, L., Zhang, X. Zosky, J.E.. Nichols, T.E., Poldrack, R.A. and T. Schonberg “Variability in the analysis of a single neuroimaging dataset by many teams,” Nature 582: 84-88, 2020.

Mitsis, G.D., Christodoulakis, M., Anastasiadou, M., Papathanasiou, E.S., Papacostas, S.S., and A. Hadjipapas “Multi-scale periodicities in the functional brain networks of patients with epilepsy and their effect on seizure detection,” Human Brain Mapping 41(8): 2059-2076, 2020.

Savva, A., Kassinopoulos, M., Smyrnis, I., Matsopoulos, G.K., and G.D. Mitsis “Effects of Motion-related artifacts on Dynamic Functional Connectivity using the Sliding Window Method,” Journal of Neuroscience Methods 330: 108519, 2020.

Patmanidis, S., Charalampidis, A.C., Kordonis, I., Mitsis, G.D. and G.P. Papavassilopoulos  “Individualized Tumor Growth Modeling and Prediction on Mice Skin Tumors with Maximum Likelihood Estimators,” Computer Methods and Programs in Biomedicine 185: 105165, 2020.

Elting, J.W., Sanders, M.L., Panerai, R.B., Aries, M., Bor-Seng-Shu, E., Caicedo, A., Chacon, M., Gommer, E.D., Van Huffel, S., Jara, J.L., Kostoglou, K., Mahdi, A., Marmarelis, V.Z., Mitsis, G.D., Müller, M., Nikolic, D., Nogueira, R., Payne, S.J., Puppo, C., Shin, D.C., Simpson, D.M., Tarumi, T., Yelicich, B., Zhang, R., Claassen, J.A.H.R. “Assessment of Dynamic Cerebral Autoregulation in humans: the role of blood pressure variability in reproducibility,” PLoS One, 15(1): e0227651, 2020.

Xifra-Porxas, A., Niso, G., Larivière, S., Kassinopoulos, M., Baillet, S., G.D. Mitsis and M.H. Boudrias “Older adults exhibit a more pronounced modulation of beta oscillations when performing sustained and dynamic handgrips,” Neuroimage 201: 116037, 2019.

Ghosh, A., Dal Maso, F., Roig, M., Mitsis, G.D., and M.H. Boudrias “Unfolding the effects of acute cardiovascular exercise on motor learning: A deep learning approach,” Frontiers in Neuroscience 13: 1215, 2019.

Kassinopoulos, M. and G.D. Mitsis “Identification of Physiological Response Functions to Correct for Fluctuations in Resting-State fMRI related to Heart Rate and Respiration,” Neuroimage 202, 116150, 2019.

Robertson, A.D., Atwi, S., Kostoglou, K., Verhoeff, P., Mitsis, G.D., Marzolini, S. and B.J. Macintosh “Cerebrovascular pulsatility during rest and exercise reflects hemodynamic impairment in stroke and cerebral small vessel disease,” Ultrasound in Medicine and Biology 45(12), 3116-3127, 2019.

Kostoglou, K., Robertson, A.D., Macintosh, B.J. and G.D. Mitsis “A novel framework for estimating time-varying multivariate autoregressive models and application to cardiovascular responses to acute exercise,” IEEE Transactions on Biomedical Engineering 66 (11), 3257-3266, 2019.

Sanders, M.L., Elting, J.W, Panerai, R.B., Aries, M., Bor-Seng-Shu, E., Caicedo, A., Chacon, M., Gommer, E., Van Huffel, S., Jara, J.L., Kostoglou, K., Mahdi, A., Marmarelis, V.Z., Mitsis, G.D., Müller, M., Nikolic, D., Nogueira, R., Payne, S.J., Puppo, C., Shin, D.C., Simpson, D.M., Tarumi, T., Yelicich, B., Zhang, R., Claassen, J.A.H.R., ”Dynamic cerebral autoregulation reproducibility is affected by physiological variability,” Frontiers in Physiology 10: 865, 2019.

Lariviere, S., Xifra-Porxas, A., Kassinopoulos, M., Niso, G., Baillet, S., Mitsis, G.D. and M.H. Boudrias, “Functional and effective reorganization of the aging brain during unimanual and bimanual hand movements,” Human Brain Mapping 40 (10): 3027-3040, 2019.

Savva, A., G.D. Mitsis and G.K. Matsopoulos “A Comprehensive Study of the Sliding Window Technique for Assessing Dynamic Functional Connectivity in Resting-State fMRI”, Brain and Behavior 9 (4): e01255, 2019.

Anastasiadou, M., Christodoulakis, M., Papathanasiou, E.S., Papacostas, S.S., Hadjipapas, A. and G.D. Mitsis “The effect of reference choice on long-duration EEG functional brain network characteristics and their correlation to seizure onset in patients with epilepsy,” Frontiers in Neuroscience 13: 221, 2019.

Prokopiou, P., Pattinson K.T.S., Wise, R.G. and G.D. Mitsis “Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the human brain using BOLD-fMRI,” Neuroimage 186 (2): 533-548, 2019.

Kostoglou, K., Schondorf, R. and G.D. Mitsis “Estimation of time-varying, multiple-input nonlinear systems using basis expansions,” Signal Processing 155: 287-300, 2019.

Shen, C.F., Guilbault, C., Li, X., Elahi, S.M., Ansorge, S., Kamen, A., and Rénald Gilbert "Development of suspension adapted Vero cell culture process technology for production of viral vaccines".  National Library of Medicine. 2019. DOI: 10.1016/j.vaccine.2019.07.003

Gélinas, J.F., Azizi, H., Kiesslich, S., Lanthier, S., Perdersen, J., Chahal, P.S., Ansorge, S., Kobinger, G., Gilbert, R., and Amine A Kamen "Production of rVSV-ZEBOV in serum-free suspension culture of HEK 293SF cells". National Library of Medicine. 2019.  DOI: 10.1016/j.vaccine.2019.09.044

Kiesslich, S., Vila-Chã Losa, J.P. Gélinas, J.F., and Amine A Kamen. "Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X™ hydro fixed-bed". National Library of Medicine. 2019. 310:32-39. DOI: 10.1016/j.jbiotec.2020.01.015.

Farnós, O., Gelaye, E., Trabelsi, K., Bernier, A., Subramani, K., Kallel, H., Yami, M., and Amine A Kamen. "Establishing a Robust Manufacturing Platform for Recombinant Veterinary Vaccines: An Adenovirus-Vector Vaccine to Control Newcastle Disease Virus Infections of Poultry in Sub-Saharan Africa". National Library of Medicine. 2019. 26;8(2):E338. doi: 10.3390/vaccines8020338.

Moço, P.D., Aharony, N., and Amine Kamen. "Adeno-Associated Viral Vectors for Homology-Directed Generation of CAR-T Cells". National Library of Medicine. 2019. 15(1):e1900286. DOI: 10.1002/biot.201900286.

Sharir-Ivry A, Xia Y. "Non-catalytic binding sites induce weaker long-range evolutionary rate gradients than catalytic sites in enzymes". Journal of Molecular Biology 431: 3860-3870 (2019).

Ghadie MA, Xia Y. "Estimating dispensable content in the human interactive". Nature Communications 10: 3205 (2019).

Sharir-Ivry A, Xia Y. Using pseudoenzymes to probe evolutionary design principles of enzymes". Evolutionary Bioinformatics 15: 1-4 (2019).

Chen YF, Xia Y. "Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes". PLoS Computational Biology 15: e1006762 (2019).

Chauvet, L., Heris, HK, Ehrlicher, AJ, Hendricks, AG. “Dynamic crosslinking of the actin cytoskeleton governs cell mechanics at long timescales” Molecular Biology of the Cell (2020) https://www.molbiolcell.org/doi/10.1091/mbc.E19-09-0504

Chaudhary, AR, Lu, H, Krementsova. EB, Bookwalter, CS, Trybus, KM, Hendricks, AG, “MAP7 regulates organelle transport by recruiting kinesin-1 to microtubules” Journal of Biological Chemistry 294(26) (2019) 10160-10171 DOI: https://doi.org/10.1074/jbc.RA119.008052

 

2018

Yoshie, H. Koushki, N., Kaviani, R., Tabatabaei, M., Rajendran, K., Dang q., Husain, A., Yao, S., Li C., Sullivan, J.K., Saint-Geniez, M., Krishnan, R., Ehrlicher, A.J. Traction Force Screening Enabled by Complaint PDMS Elastomers. Biophysical Journal. 2018; 114 (9), pp. 2194-2199. DOI: 10.1016/j.bpj.2018.02.045

Husain A, Khadka A, Ehrlicher A.J, Saint-Geniez M, Krishnan R. Substrate stiffening promotes VEGF-A function via PI3K/Akt/mTOR signaling. Frontiers in Pharmacology.

Balabanian, L., Chaudhary, A.R., Hendricks, A.G. Traffic control inside the cell: Microtubule-based regulation of cargo transport. Biochemist. 2018; 40 (2), pp. 14-17

Chaudhary, A.R., Berger, F., Berger, C.L., Hendricks, A.G. Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams. Traffic. 2018; 19 (2), pp. 111-121. DOI: 10.1111/tra.12537. 

Gutiérrez-Granados, S., Cervera, L., Kamen, A., Gòdia, F. Advancements in mammalian cell transient gene expression (TGE) technology for accelerated production of biologics. Critical Reviews in Biotechnology. 2018. 38 (6), pp. 918-940. DOI: 10.1080/07388551.2017.1419459

Robert, M.-A., Nassoury, N., Chahal, P.S., Venne, M.-H., Racine, T., Qiu, X., Kobinger, G., Kamen, A., Gilbert, R., Gaillet, B. Gene Transfer of ZMapp Antibodies Mediated by Recombinant Adeno-Associated Virus Protects Against Ebola Infections. Human Gene Therapy. 2018. 29 (4), pp. 452-466. DOI: 10.1089/hum.2017.10.

Chavez-Pena, C., Kamen, A.A. RNA interference technology to improve the baculovirus-insect cell expression system. Biotechnology Advances. 2018. 36 (2), pp. 443-451. DOI: 10.1016/j.biotechadv.2018.01.008

Cervera, L., Kamen, A.A. Large-scale transient transfection of suspension mammalian cells for VLP production. Methods in Molecular Biology. 2018.  1674 (1), pp. 117-127. DOI: 10.1007/978-1-4939-7312-5_10.

Sharon, D., Kamen, A. Advancements in the design and scalable productions of viral gene transfer vectors. Biotechnology and Bioengineering. 2018. 115 (1), pp. 25-40. 10.1002/bit.26461DOI: 

Fuenmayor, J., Cervera, L., Gòdia, F., Kamen, A. Extended gene expression for Gag VLP production achieved at bioreactor scale. Journal of Chemical Technology and Biotechnology. 2018. 94 (1), pp. 302-308. DOI: 10.1002/jctb.5777.

Tavafoghi, M., Kinsella, J.M., Gamys, C.G., Gosselin, M., Zhao, Y.F. Silicon-doped hydroxyapatite prepared by a thermal technique for hard tissue engineering applications. Ceramics International. 2018. 44 (15), pp. 17612-17622. DOI: 10.1016/j.ceramint.2018.06.071

Jiang, T., Munguia-Lopez, J., Flores-Torres, S., Grant, J., Vijayakumar, S., de Leon-Rodriguez, A., Kinsella, J.M. Bioprintable alginate/gelatin hydrogel 3D in vitro model systems induce cell spheroid formation. Journal of Visualized Experiments. 2018. 20 (137). DOI: 10.3791/57826

Serpooshan, V., Sheibani, S., Pushparaj, P., Wojcik, M., Jang, A.Y., Santoso, M.R., Jang, J.H., Huang, H., Safavi-Sohi, R., Haghjoo, N., Nejadnik, H., Aghaverdi, H., Vali, H., Kinsella, J.M., Presley, J., Xu, K., Yang, P.C.-M., Mahmoudi, M. Effect of Cell Sex on Uptake of Nanoparticles: The Overlooked Factor at the Nanobio Interface. ACS Nano. 2018. 12 (3), pp. 2253-2266. DOI: 10.1021/acsnano.7b06212

Su, X., Fang, D., Liu, Y., Ruan, G., Seuntjens, J., Kinsella, J.M., Tran, S.D. Lyophilized bone marrow cell extract functionally restores irradiation-injured salivary glands. Oral Diseases. 2018. 24 (2), pp. 202-206. DOI: 10.1111/odi.12728. 

Sheng, R., Wang, Z., Luo, T., Cao, A., Sun, J., Kinsella, J.M. Skeleton-controlled pDNA delivery of renewable steroid-based cationic lipids, the endocytosis pathway analysis and intracellular localization. International Journal of Molecular Sciences. 2018. 19 (2). DOI: 10.3390/ijms19020369

Zhuang, X., Zhao, D., Yang, P., Jia, Y., Liang, R., Zhao, Q., Han, C., Kinsella, J.M., Sheng, R., Li, J. 99mTc-labeled rHuEpo for imaging of the erythropoietin receptor in tumors. Journal of Labelled Compounds and Radiopharmaceuticals. 2018. 61 (2), pp. 77-83. DOI: 10.1002/jlcr.3586

Mahshid, S., Lu, J., Abidi, A.A., Sladek, R., Reisner, W.W., Ahamed, M.J. Transverse dielectrophoretic-based DNA nanoscale confinement. Scientific Reports. 2018. 8 (1). DOI: 10.1038/s41598-018-24132-5

Jalali, M., AbdelFatah, T., Mahshid, S.S., Labib, M., Sudalaiyadum Perumal, A., Mahshid, S. A Hierarchical 3D Nanostructured Microfluidic Device for Sensitive Detection of Pathogenic Bacteria. Small. 2018. 14 (35). DOI: 10.1002/smll.201801893

Mahshid S., Lu J.*, Abidi A. A.*, Sladek R., Reisner W., Ahamed M.J. Transverse Dielectrophoretic (DEP) based DNA Nanoscale Confinement. Scientific Reports. 2018. 

Patmanidis, S., Charalampidis, A.C., Kordonis, I., Mitsis, G.D., Papavassilopoulos, G.P. Tumor growth modeling: Parameter estimation with Maximum Likelihood methods. Computer Methods and Programs in Biomedicine. 2018. 160 (1), pp. 1-10. DOI: 10.1016/j.cmpb.2018.03.014

Iakovidou, N.D., Laskaris, N.A., Tsichlas, C., Manolopoulos, Y., Christodoulakis, M., Papathanasiou, E.S., Papacostas, S.S., Mitsis, G.D. A symbolic dynamics approach to Epileptic Chronnectomics: Employing strings to predict crisis onset. Theoretical Computer Science. 2018. 710 (2), pp. 116-125. DOI: 10.1016/j.tcs.2017.02.023

Kostoglou, K., Schondorf, R., Benoit, J., Balegh, S., Mitsis, G.D. Prediction of the time to syncope occurrence in patients diagnosed with vasovagal syncope. Acta Neurochirurgica, Supplementum. 2018. 126 (4), pp. 313-316. 

Prokopiou, P., Pattinson K.T.S., Wise, R.G. and G.D. Mitsis. Modeling of dynamic cerebrovascular reactivity to spontaneous and externally induced CO2 fluctuations in the human brain using BOLD-fMRI. Neuroimage. 2018. 186 (7), pp. 533-548. 

Kostoglou, K., Schondorf, R. and G.D. Mitsis. Estimation of time-varying, multiple-input nonlinear systems using basis expansions. Signal Processing. 2018. 155 (3), pp. 287-300. DOI: https://doi.org/10.1016/j.neuroimage.2018.10.084

Sanders, M., Claassen, J., Aries, M., Bor-Seng-Shu, E., Caicedo, A., Chacon, M., Gommer, E., Van Huffel, S., Jara, J., Kostoglou, K., Mahdi, A., Marmarelis, V., Mitsis, G.D., Müller, M., Nikolic, D., Nogueira, R., Payne, S., Puppo, C., Shin, D., Simpson, D., Tarumi, T., Yelicich, B., Zhang, R., Panerai, R., Elting, J.W. Reproducibility of dynamic cerebral autoregulation parameters: a multi-centre, multi-method study. Physiological Measurement. 2018

Iacovides, D., Loizides, C.L., Mitsis, G.D. and K.S. Strati. Whole Transcriptome Sequencing of 5-FU Sensitive and 5-FU Resistant Tumors in a Mouse Model of de novo Carcinogenesis. Data in Brief. 2018. 20 (1), pp. 1602-1606.

Patmanidis, S., Charalampidis, A.C., Kordonis, I., Mitsis, G.D. and G.P. Papavassilopoulos.  Tumor Growth Modeling: Parameter estimation with Maximum Likelihood methods. Computer Methods and Programs in Biomedicine. 2018. 160 (1).

Akovidou, N.D., Laskaris, N.A., Tsichlas, C., Christodoulakis, M., Papathanasiou, E.S., Papacostas, S.S, and G.D. Mitsis. A symbolic dynamics approach to Epileptic Chronnectomics: employing strings to predict crisis onset. Theoretical Computer Science. 2018. 710 (5), pp. 116-125. 

G.D. Mitsis. On the choice of optimal stimulus type for assessing dynamic cerebral autoregulation. The Journal of Physiology. 2018. 

Xifra-Porxas, A., Kostoglou, K., Larivière, S., Niso, G., Kassinopoulos, M., Boudrias, M. H., and Mitsis, G. D. Identification of Time-Varying Cortico-cortical and Cortico-Muscular Coherence during Motor Tasks with Multivariate Autoregressive Models. Proc. 40th Ann. Intern. Conf. IEEE EMBS. 26, pp. 1024-27

Durand, A., Achilleos, C., Iacovides, D., Strati, K.S., Mitsis, G.D. and J. Pineau. Contextual Bandits for Adapting Treatment in a Mouse Model of de Novo Carcinogenesis. Proceedings of Machine Learning Research: Machine Learning in Heatlhcare. 2018. 85 (1).

Kostoglou, K., Schondorf, R., Benoit, J., Balegh, S. and G.D. Mitsis. Prediction of the Time to Syncope Occurrence in Patients Diagnosed with Vasovagal Syncope Intracranial Pressure & Neuromonitoring XVI. 2018. 

Clancy, K. F.A., Dery, S., Laforte, V., Shetty, P., Juncker, D., Nicolau, D.V, Protein microarray spots are modulated by patterning method, surface chemistry and processing conditions. Biosensors & Bioelectronics. 2018. pp 397-407. DOI: 10.1016/j.bios.2018.09.027

Dobroiu, S., van Delft, F.C.M.J.M., Aveyard-Hanson, J., Shetty, P., Nicolau, D.V. Fluorescence Interference Contrast-enabled structures improve the microarrays performance. Biosensors & Bioelectronics

van Delft, F.C.M.J.M., Ipolitti, G., Nicolau, D.V. Jr., Sudalaiyadum Perumal, A., Kaspar, O., Kheireddine, S., Wachsmann-Hogiu, Nicolau, D.V. Something has to give: Scaling combinatorial computing by biological agents exploring physical networks encoding NP-complete problems. Royal Society of UK Interface Focus. 2018. 8 (6). DOI: 10.1098/rsfs.2018.0034

Van Cleuvenbergen, S., Smith, Z.J., Deschaume, O., Bartic, C., Wachsmann-Hogiu, S., Verbiest, T., van der Veen, M.A. Morphology and structure of ZIF-8 during crystallisation measured by dynamic angle-resolved second harmonic scattering. Nature Communications. 2018. 9 (1). DOI: 10.1038/s41467-018-05713-4

Baum, O., Wachsmann-Hogiu, S., Sobol, E. Thermo-mechanical mechanism of laser-assisted alteration and stabilization of micro pore structure in eye-sclera. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. 2018. 10496. DOI: 10.1117/12.2289885

van Delft, F., Ipolitti, G., Nicolau, D.V., Sudalaiyadum Perumal, A., Kašpar, O., Kheireddine, S. , Wachsmann-Hogiu, S. Something has to give: scaling combinatorial computing by biological agents exploring physical networks encoding NP-complete problems. Interface Focus. 2018. 8 (6). DOI: 10.1098/rsfs.2018.0034

Kordon, M.M., Szczurek A,, Berniak A., Szelest, O., Solarczyk, K., Tworzydło, M., Wachsmann-Hogiu S., Vaahtokari, A., Cremer, C., Pederson, T., Dobrucki, J.W. PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks. The FASEB Journal. 2018. 33 (2). DOI: 10.1096/fj.201801379R

Korkmaz A., Kenton, M., Aksin, G., Kahraman, M., Wachsmann-Hogiu, S. Inexpensive and flexible substrates on adhesive tape based on biosilica plasmonic nanocomposites. ACS Applied Nano Materials. 2018. 

Hilt, S., Altman, R., Kálai, T., Maezawa I, Gong, Q, Wachsmann-Hogiu, S.  Jin, L.W, and  Voss, J.C.. A Bifunctional Anti-Amyloid Blocks Oxidative Stress and the Accumulation of Intraneuronal Amyloid-Beta. Molecules. 2018. 23 (8). DOI: 10.3390/molecules23082010

Ghadie, M.A., Coulombe-Huntington, J., Xia, Y. Interactome evolution: insights from genome-wide analyses of protein–protein interactions. Current Opinion in Structural Biology. 2018. 50 (1), pp. 42-48. DOI: 10.1016/j.sbi.2017.10.012

Bertomeu, T., Coulombe-Huntington, J., Chatr-aryamontri, A., Bourdages, K.G., Coyaud, E., Raught, B., Xia, Y., Tyers, M. A highresolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome. Molecular and Cellular Biology. 2018. 38 (1). DOI: 10.1128/MCB.00302-17

Sharir-Ivry A*, Xia Y. Nature of long-range evolutionary constraint in enzymes: insights from comparison to pseudoenzymes with similar structures. Molecular Biology and Evolution. 2018. 35 (11), pp. 2597-2606. DOI: 10.1093/molbev/msy177

Ghadie MA*, Coulombe-Huntington J*, Xia Y. Interactome evolution: insights from genome-wide analyses of protein-protein interactions. Current Opinion in Structural Biology. 2018. 50.

Bertomeu T, Coulombe-Huntington J, Chatr-aryamontri A, Bourdages KG, Coyaud E, Raught B, Xia Y, Tyers M. A high-resolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome. Molecular and Cellular Biology. 2018. 38 (302).

Chen YF*, Xia Y. Convergent perturbation of the human domain-resolved interactome by viruses and mutations inducing similar disease phenotypes. Dana-Farber Cancer Institute Center for Cancer Systems Biology. 2018. 15 (2). DOI: 10.1371/journal.pcbi.1006762

Ghadie MA*, Coulombe-Huntington J*, Xia Y. Interactome evolution: insights from genome-wide analyses of protein-protein interactions. Dana-Farber Cancer Institute Center for Cancer Systems Biology. 2018. 50 (2), pp. 42-48. DOI: 10.1016/j.sbi.2017.10.012

 

Conference proceedings

Seeing and Building Tumours: The Role of Advanced Materials in Oncology. Lady Davis Medical Research Institute, Oxford University-McGill University Biophotonics Workshop. Montreal, QC, Canada, 2018. [Prof. Matt Kinsella]

Seeing and Building Tumours: The Role of Advanced Materials in Oncology. Purdue University Weldon School of Biomedical Engineering Distinguished Series, West Lafayette, Indiana, USA. 2018.  [Prof. Matt Kinsella]

Seeing and Building Tumours: The Role of Advanced Materials in Oncology. Concordia University Chemistry Departmental Seminar Series. Montreal, QC, Canada. 2018.  [Prof. Matt Kinsella]

Seeing and Building Tumours: The Role of Advanced Materials in Oncology. North Carolina State University Material Science and Engineering Seminar Series. Raleigh, North Carolina, USA. 2018. [Prof. Matt Kinsella]

Seeing and Building Tumours: The Role of Advanced Materials in Oncology. Illinois Institute of Technology Biomedical Engineering Seminar Series. Chicago, Illinois, USA. 2018.  [Prof. Matt Kinsella]

Tissue fabrication using 3D printing: a bloody story. Stem Cell & Regenerative Medicine Annual Symposium. London, ON, Canada. 2018. [Prof. Matt Kinsella]

Bioprintable Alginate-Gelatin Bioink For Three-Dimensional Cell Culture: A Tool For Cancer Research. Biomedical Engineering Society Annual Meeting. Atlanta, GA. 2018. [Prof. Matt Kinsella]

Post-extrusion yield strength as a key material attribute on structural stability in Bioprinting. Biomedical Engineering Society Annual Meeting. Atlanta, GA. 2018. [Prof. Matt Kinsella]

Developing Bioink Formulations that Promote Multicellular Tumour Organoid Growth. SelectBIO-Bioprinting. Rotterdam, The Netherlands. 2018. [Prof. Matt Kinsella]

PLTL: Experiences from both sides of the desk. Annual Meeting of the American Chemical Society (ACS). New Orleans, LA, USA. 2018. [Prof. Matt Kinsella]

Bioprinting Tumor Models with Mechanically and Biochemically Tunable Bioinks that Mimic the Native Tumor Microenviroment. ET-CMOS. Whistler, BC, Canada. 2018 [Prof. Matt Kinsella]

Bioprinting Tumor Models with Mechanically and Biochemically Tunable Bioinks that Mimic the Native Tumor Microenviroment. SelectBIO-Bioprinting. Rotterdam, The Netherlands. 2018. [Prof. Matt Kinsella]

Nikolaou, F., Orphanidou, C., Murphy, K., Wise, R. G., and G.D. Mitsis. Investigation Of Interaction Between Physiological Signals And fMRI Dynamic Functional Connectivity Using Independent Component Analysis. Proc. 40th Anniversary International Conference IEEE. Honolulu, HI, USA. 2018. [Prof Georgios Mitsis].

Prokopiou, P. Kassinopoulos, M., Xifra-Porxas, A. Boudrias, M.H., Mitsis, G.D. Estimating hemodynamic response functions using resting-state EEG-fMRI data acquired during wakefulness with eyes open. Sixth Biennial Conference on Resting State and Brain Connectivity. Montreal, QC, Canada. 2018. [Prof Georgios Mitsis]

 

2017

Egan P, Moore JR, Ehrlicher AJ, Weitz DA, Schunn CD, Cagan J, LeDuc PR. Robust mechanobiological behavior emerges in heterogenous myosin system. Proceedings of the National Academy of Sciences. 2017; 114(39), pp. E8147-E8154. DOI: 10.1073/pnas.1713219114

Yissachar N, Zhou Y, Ung L, Lai NY, Mohan JF, Ehrlicher AJ, Weitz DA, Kasper DL, Chiu IM, Mathis D, Benoist C. An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk. Cell. 2017; 168(6): 1135-1148. e12. DOI: 10.1016/j.cell.2017.02.009.

Asgari M, Latifi N, Heris HK, Vali H, Mongeau L. In vitro fibrillogenesis of tropocollagen type III in collagen type i affects its relative fibrillar topology and mechanics. Scientific Reports. 2017; 7(1). DOI: 10.1038/s41598-017-01476-y

Balabanian L, Berger CL, Hendricks AG. Acetylated microtubules are preferentially bun-dled leading to enhanced kinesin-1 motility. Biophysical Journal. Selected for the Collection: Microtubules and Motors. 2017; 113: 1-10. DOI: 10.1016/j.bpj.2017.08.009

Chaudhary AR, Berger F, Berger CL, Hendricks AG. Tau directs intracellular trafficking by regulating the forces exerted by kinesin and dynein teams. Traffic. 2017; 1-11. DOI: 10.1111/tra.12537

Hendricks AG, Goldman YE. Measuring molecular forces using calibrated optical tweezers in living cells. Methods in Molecular Biology. 2017; 537-552. DOI: 10.1007/978-1-4939-6421-5_21

Yogev S, Maeder CI, Cooper R, Horowitz M, Hendricks AG, Shen K. Local inhibition of microtubule dynamics by dynein is required for neuronal cargo distribution in C. elegans. Nature Communications. 2017; 15063: 8. DOI: 10.1038/ncomms15063

Fuenmayor, J., Gòdia, F., Cervera, L., 2017. Production of virus-like particles for vaccines. New Biotechnology. 2017; 39, 174-180. DOI: 10.1016/j.nbt.2017.07.010

Kligman R, Gilbert R, Kamen A. The engineering, use, and mass production of adeno-associated virus as a vector for gene therapy. Current Topics in Virology. 2017; 14: 1-16.

Manceur AP, Zou W, Marcil A, Paquet E, Gadoury C, Jaentschke B, Li X, Petiot E, Durocher Y, Baardsnes J, Rosa-Calatrava M, Ansorge S, Kamen A. Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza. PLoS One. 2017; 12(6): e0180314. PubMed PMID: 28662134; PubMed Central PMCID: PMC5491208. DOI: 10.1371/journal.pone.0180314

Milián E, Julien T, Biaggio R, Venereo-Sanchez A, Montes J, Manceur AP, Ansorge S, Petiot E, Rosa-Calatrava M, Kamen A. Accelerated mass production of influenza virus seed stocks in HEK-293 suspension cell cultures by reverse genetics. Vaccine. 2017 Jun 8; 35(26): 3423-3430. PubMed PMID: 28495315. DOI: 10.1016/j.vaccine.2017.04.065

Petiot E, Ansorge S, Rosa-Calatrava M, Kamen A. Critical phases of viral production processes monitored by capacitance. J Biotechnol. 2017 Jan 20; 242: 19-29. PubMed PMID: 27867077. DOI: 10.1016/j.jbiotec.2016.11.010

Robert MA, Chahal PS, Audy A, Kamen A, Gilbert R, Gaillet B. Manufacturing of recombinant adeno-associated viruses using mammalian expression platforms. Biotechnol J. 2017 Mar; 12(3). PubMed PMID: 28177193. DOI: 10.1002/biot.201600193

Robert MA, Nassoury N, Chahal PS, Venne MH, Racine T, Xiangguo Q, Kobinger G, Kamen A, Rénald G, Bruno G. Gene transfer of Zmapp antibodies mediated by recombinant adeno-associated virus protects against ebola infections. Hum Gene Ther. 2017 Nov 27. PubMed PMID: 29179602. DOI: 10.1089/hum.2017.101

Stav-Noraas TE, Edelmann RJ, Poulsen LC, Sundnes O, Phung D, Kuchler AM, Muller F, Kamen A, Haraldsen G, Kaarbo M, Hol J. Endothelial IL-33 expression is augmented by adenoviral activation of the DNA damage machinery. J Immunol. 2017 Apr 15; 198(8): 3318-3325. PubMed PMID: 28258201. DOI: 10.4049/jimmunol.1600054

Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal P, Bourget L, Ansorge S, Gilbert R, Henry O, Kamen A. Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line. Vaccine. 2017 Jul 24; 35(33): 4220-4228. PubMed PMID: 28648546. DOI: 10.1016/j.vaccine.2017.06.024

Flores-Torres S, Sakho AM, Jiang T, Kort Mascort J, Jang J, Kinsella JM. 3D bioprinted environments for toxicological studies on multi-cellular tumor spheroids. Tissue Engineering Part A. 2017; 23: S59-S59.

Jiang T, Munguia-Lopez JG, Grant J, Vijayakumar S, De Leon-Rodriguez A, Kinsella JM. Directing the self-assembly of tumor spheroids by bioprinting cellular heterogeneous models within alginate/gelatin hydrogels. Scientific Reports. 2017; 7: 4575. DOI: 10.1038/s41598-017-04691-9

Jiang T, Munguia-Lopez JG, Gu K, Bavoux MM, Flores-Torres S, Kort-Mascort J, Grant J, Vijayakumar S, De Leon-Rodriguez A, Kinsella JM. Alginate/gelatin hydrogels as bioprintable inks directing tumor spheroid formation. Tissue Engineering Part A. 2017; 23: S24-S24. DOI: 10.3791/57826

Malca M, Bao H, Bastaille T, Saadé NK, Kinsella JM, Frĭšcíc T, Moores A. Mechanically-induced solvent-free direct synthesis of bismuth sulfide nanoparticles for use as contrast agents in computed tomography imaging. Chemistry of Materials. 2017; 29: 7766-7773.

Su X, Fang D, Liu Y, Ruan G, Seuntjens J, Kinsella JM, Tran SD. Lyophilized bone marrow cell extract functionally restores irradiation-injured salivary glands. Oral Diseases. 2017. DOI: 10.1111/odi.12728

Xu J, Niu G, Wei X, Lan M, Zeng L, Kinsella JM, Sheng R. A family of multi-color anthracene carboxyimides: Synthesis, spectroscopic properties, solvatochromic fluorescence and bioimaging application. Dyes and Pigments. 2017; 139: 166-173. DOI: 10.1016/j.dyepig.2016.11.056

Iakovidou ND, Laskaris NA, Tsichlas C, Christodoulakis M, Papathanasiou ES, Papacostas SS, Mitsis GD. A symbolic dynamics approach to epileptic chronnectomics: employing strings to predict crisis onset. Theoretical Computer Science. 2017; 710: 116-125. DOI: 10.1016/j.tcs.2017.02.023 - I.F. 0.94.

Kostoglou K, Michmizos KP, Stathis P, Sakas D, Nikita KS, Mitsis GD. Prediction of the unified Parkinson's disease rating scale improvement in Deep Brain Stimulation. IEEE Transactions on Biomedical Engineering. 2017; 64 (5): 1123-1130 (I.F. 3.557). DOI: 10.1109/TBME.2016.2591827

Michmizos KP, Lindqvist B, Wong S, Hargreaves EL, Mitsis GD, Danish SF, Nikita KS. Computational neuromodulation: Future challenges for Deep Brain Stimulation. IEEE Signal Processing Magazine. 2017; 34(2): 114-119. DOI: 10.1109/MSP.2016.2639554

Patmanidis S, Charalampidis AC, Kordonis I, Mitsis GD, Papavassilopoulos GP. Comparing methods for parameter estimation of the Gompertz tumor growth model. IFAC-PapersOnLine. 2017; 50(1), 12203-12209. DOI: 10.1016/j.ifacol.2017.08.2289

Boysen RI, Schwarz LJ, Nicolau DV, Hearn MTW. Molecularly imprinted polymer membranes and thin films for the separation and sensing of biomacromolecules. Journal of Separation Science. 2017; 40(1): 314-335. DOI: 10.1002/jssc.201600849

Hanson KL, Fulga F, Dobroiu S, Solana G, Kaspar O, Tokarova V, Nicolau DV. Polymer surfaces properties control the function of heavy meromyosin in dynamic nanodevices. Biosensors & Bioelectronics. 2017; 93: 305-314. DOI: 10.1016/j.bios.2016.08.061

Avella-Oliver M, Puchades R, Wachsmann-Hogiu S, Maquieira A. Label-free SERS analysis of proteins and exosomes with large-scale substrates from recordable compact disks. Sensors and Actuators B Chemical. 2017 Jun; 252. DOI: 10.1016/j.snb.2017.06.058

Baum O, Wachsmann-Hogiu S, Milner T, Sobol E. Laser-assisted formation of micropores and nanobubbles in sclera promote stable normalization of intraocular pressure. Laser Physics Letters. 2017 Jun; 14(6): 065601. DOI: 10.1088/1612-202X/aa6b1a

Ferraz de Menezes R, Harvey CM, Márquez de Martínez Gerbi ME, Smith ZJ, Smith D, Ivaldi JC, Phillips A, Chan JW, Wachsmann-Hogiu S. Fs-laser ablation of teeth is temperature limited and provides information about the ablated components. Journal of Biophotonics. 2017 May. DOI: 10.1002/jbio.201700042

Hilt S, Rojalin TP, Viitala T, Koivuniemi A, Bunker A, Wachsmann-Hogiu S, Kalai T, Hideg K, Yliperttula M, Voss JC. Oligomerization Alters Binding Affinity Between Amyloid Beta and a Modulator of Peptide Aggregation. The Journal of Physical Chemistry. 2017; C/10. DOI: 10.1021/acs.jpcc.7b06164

Kahraman M, Mullen ER, Korkmaz A, Wachsmann-Hogiu S. Fundamentals and applications of SERS-based bioanalytical sensing. Nanophotonics. 2017 Jan; 6(5). DOI: 10.1515/nanoph-2016-0174.

Rojalin T, Saari H, Somersalo P, Laitinen S, Turunen M, Viitala T, Wachsmann-Hogiu S, Smith ZJ, Yliperttula M. Time-resolved SERS for characterizing extracellular vesicles. SPIE BiOS. 2017 Feb. DOI: 10.1117/12.2271865

Sobol E, Baum O, Shekhter A, Wachsmann-Hogiu S, Shnirelman A, Alexandrovskaya Y, Sadovskyy I, Vinokur V. Laser-induced micropore formation and modification of cartilage structure in osteoarthritis healing. Journal of Biomedical Optics. 2017 May; 22(9): 091515. DOI: 10.1117/1.JBO.22.9.091515

Tong L, Kauer J, Wachsmann-Hogiu S, Chu K, Dou H, Smith ZJ. A new red cell index and portable RBC analyzer for screening of iron deficiency and Thalassemia minor in a Chinese population. Scientific Reports 12. 2017; 7(1). DOI: 10.1038/s41598-017-11144-w

Bertomeu T, Coulombe-Huntington J, Chatr-aryamontri A, Bourdages KG, Coyaud E, Raught B, Xia Y, Tyers M. A high-resolution genome-wide CRISPR/Cas9 viability screen reveals structural features and contextual diversity of the human cell-essential proteome. Molecular and Cellular Biology. 2017 Oct. DOI: 10.1128/MCB.00302-17.

Ghadie MA, Coulombe-Huntington J, Xia Y. Interactome evolution: insights from genome-wide analyses of protein-protein interactions. Current Opinion in Structural Biology. 2017 Nov. DOI: 10.1016/j.sbi.2017.10.012

Ghadie M, Lambourne L, Vidal M, Xia Y. Domain-based prediction of the human isoform interactome provides insights into the functional impact of alternative splicing. PLoS Computational Biology. 2017; 13: e1005717. DOI: 10.1371/journal.pcbi.1005717

Jacobs C, Lambourne L, Xia Y, Segrè D. Upon accounting for the impact of isoenzyme loss, gene deletion costs anticorrelate with their evolutionary rates. PLoS ONE. 2017; 12: e0170164. DOI: 10.1371/journal.pone.0170164

Coulombe-Huntington J, Xia Y. Network centrality analysis in fungi reveals complex regulation of lost and gained genes. PLoS ONE. 2017; 12: e0169459. DOI: 10.1371/journal.pone.0169459

Qin L, Chen C, Chen L, Xue R, Ou-Yang M, Zhou C, Zhao S, He Z, Xia Y, He J, Liu P, Zhong N, Chen X. Worldwide malaria incidence and cancer mortality are inversely associated. Infectious Agents and Cancer. 2017; 12: 14. DOI: 10.1186/s13027-017-0117-x

Sharir-Ivry A, Xia Y. The impact of native state switching on protein sequence evolution. Molecular Biology and Evolution. 2017; 34: 1378-1390. DOI: 10.1093/molbev/msx071.

 

Conference proceedings

Insect Cell Culture Technology for Manufacturing Virus-Like Particles and Viral Vectors. ISBioTech., Washington, DC, USA, March 6, 2017. [Prof. Amine Kamen]

Bioprinting heterogeneous 3D tumor models. Society for Biomaterials (SFB), Minneapolis, MN, USA, April 2017. [Prof. J. Matt Kinsella] (Jiang, T., Munguia-Lopez, JG., Grant, J., Vijayakumar, S.)

Process Intensification to address the challenges of viral vectors manufacturing for gene and cell therapy. ESACT, Lausanne, Switzerland, May 14, 2017. [Prof. Amine Kamen]

Optical Immunosenosr for detection of pathogens. 100th Canadian Society of Chemistry (CSC), Toronto, ON, Canada, May 28 – June 1, 2017. [Prof. Sara Mahshid]

Protein-specific empirical model of protein adsorption on surfaces. Single-use technologies II: Bridging Polymer Science to Biotechnology Applications, Tomar, Portugal, May 2017. [Prof. Dan Nicolau]

Surface Enhanced Raman Spectroscopy (SERS) for bioanalytical sensing (SERS-based bioanalytical sensing). XXXVI Biennial Chemistry Meeting, Sitges, Spain, June 26, 2017. [Prof. Sebastian Wachsmann-Hogiu]

The impact of native state switching on protein sequence evolution at the residue level. Annual Meeting of the Society of Molecular Biology and Evolution (SMBE), Austin, Texas, USA, July 2017. [Prof. Yu (Brandon) Xia]

Using high-resolution models of the cell to make sense of big data in biology and medicine. International Conference on Big Data in Biological and Medical Sciences, Xi’an, Shaanxi, China, July 2017. [Prof. Yu (Brandon) Xia]

Biological networks at atomic resolution. Center for Bioinformatics, Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing, China, July 2017. [Prof. Yu (Brandon) Xia]

Bioanalytical sensing with Raman and SERS spectroscopy. SAS tour speaker engagement, 1-st Purdue Symposium on Applied Spectroscopy and Biophotonics, Purdue University, West Lafayette, IN, USA, September 16, 2017. [Prof. Sebastian Wachsmann-Hogiu]

Accelerated Generation of Candidate Influenza Viral Vaccine to Respond to Pandemic Situations. 13th PEACe Conference, Valencia, Spain, September 24-28, 2017. [Prof. Amine Kamen]

Computing with biological agents. 43rd International Conference on Micro and Nanoengineering, Braga, Portugal, September 2017. [Prof. Dan Nicolau]

3D-Bioprinted Breast Cancer Models for Toxicological Screening. Biomedical Engineering Society (BMES), Phoenix, AZ, USA, October 2017. [Prof. J. Matt Kinsella]

The Composition of Alginate/Gelatin Composite Hydrogel Bioinks Direct the Formation of Tumor Spheoids. Biomedical Engineering Society (BMES), Phoenix, AZ, USA, October 2017. [Prof. J. Matt Kinsella]

Virus-like particles and nanoparticles for gene delivery and vaccination. 11th International Congress of Pharmaceutical Sciences (CIFARP), Ribeirão Preto, Brazil, November 14-18, 2017. [Prof. Amine Kamen]

Engineering Nanomaterials to Diagnose and Track Cancer from the Cellular to the Tissue Level. V ISNS Nanomedicine Conference, Montreal, QC, CA, November 2017. [Prof. J. Matt Kinsella]

Advanced spectroscopic tools for biomedical applications. University of Basel, Switzerland, December 5th, 2017. [Prof. Sebastian Wachsmann-Hogiu]

 

2016

Akbari A, Rahim AA, Ehrlicher AJ, Ghoshal S. Growth and adhesion of a model hydrocarbon degrading bacteria on hexadecane in sub-micron pores. Environmental Science and Technology Letters. 2016; 3(11): 399-403.

Khavari A, Nyden M, Weitz DA, Ehrlicher AJ. Composite alginate gels for tunable cellular microenvironment mechanics. Scientific Reports. 2016; 6: 30854. doi: 10.1038/srep30854.

Venereo-Sanchez A, Gilbert R, Simoneau M, Caron A, Chahal P, Chen W, Ansorge S, Li X, Henry O, Kamen A. Hemagglutinin and neuraminidase containing virus-like particles produced in HEK-293 suspension culture: An effective influenza vaccine candidate. Vaccine. 2016; 34(29): 3371-3380.

Shen CF, Jacob D, Zhu T, Bernier A, Shao Z, Yu X, Patel M, Lanthier S, Kamen A. Optimization and scale-up of cell culture and purification processes for production of an adenovirus vectored tuberculosis vaccine candidate. Vaccine. 2016; 34(29): 3381-3387.

Emmerling VV, Pegel A, Milian EG, Venereo-Sanchez A, Kunz M, Wegele J, Kamen A, Kochanek S, Hoerer M. Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells. Biotechnol J. 11(2): 290-297.

Thompson CM, Aucoin MG, Kamen A. Production of Virus-Like Particles for Vaccination. Methods Mol Biol. 2016; 1350: 299-315.

Thompson CM, Montes J, Aucoin MG, Kamen A. Recombinant Protein Production in Large-Scale Agitated Bioreactors Using the Baculovirus Expression Vector System. Methods Mol Biol. 2016; 1350: 241-61.

Xu J, Zhang Y, Zeng L, Liu J, Kinsella JM, Sheng R. A simple naphthalene-based fluorescent probe for high selective detection of formaldehyde in toffees and HeLa cells via aza-Cope reaction. Talanta. 160: 645-652.

Nicolau Jr. DV, Lard M, Korten T , van Delft, FCMJM, Persson M, Bengtsson E, Månsson A, Diez S, Linke H, Nicolau DV. Parallel computation with molecular-motor-propelled agents in nanofabricated networks. Proc. Natl. Acad. Sci. U.S.A. 2016; 113(10): 2591-2596.

Asenova E, Lin, HY, Fu E, Nicolau Jr. DV, Nicolau DV. Optimal fungal space searching algorithms. IEEE Transactions on Nanobioscience. 2016; 15(7): 613-618.

Kašpar O, Zhang, H, Tokárová V, Boysen, RI, Suñé GR, Borrise X, Perez-Murano F, Hearn MTW, Nicolau, DV. Confinement of water droplets on rectangular micro/nano-arrayed surfaces. Lab on a Chip. 2016; 16(13): 2487-2493.

Filipponi F, Livingston P, Kašpa, O, Tokárová V, Nicolau DV. Protein patterning by microcontact printing using pyramidal PDMS stamps. Biomedical Microdevices. 2016; 18. http://link.springer.com/article/10.1007%2Fs10544-016-0036-4, 2016

Nguyen MT, Chaffee AL, Boysen RI., Nicolau DV. Hearn, M.T.W. A versatile modelling approach to determine the hydrophobicity of peptides at the atomic level. Molecular Simulation. 2016; 42(4): 257-269.

Waltz X, Beaudin AE., Hanly PJ, Mitsis GD, Poulin MJ. Cerebral autoregulation impairment relies on OSA severity without effects of CPAP treatment. The Journal of Physiology. 2016; 594(23): 7089-7104.

Kostoglou K, Michmizos KP, Stathis P, Sakas, D, Nikita KS., Mitsis GD. Prediction of the Unified Parkinson's Disease Rating Scale Improvement in Deep Brain Stimulation. IEEE Transactions on Biomedical Engineering. 2016. doi: 10.1109/TBME.2016.2591827 - I.F. 2.468.

Marmarelis VZ, Mitsis GD, Shin DC, Zhang R. Multiple-input nonlinear modelling of cerebral haemodynamics using spontaneous arterial blood pressure, end-tidal CO2 and heart rate measurements. Philosophical Transactions of the Royal Society. 2016; A 374: 2067.

Nikolaou F, Orphanidou C, Papakyriakou P, Murphy K, Wise RG, Mitsis GD. Spontaneous Physiological Variability Modulates Dynamic Functional Connectivity in Resting-State fMRI. Philosophical Transactions of the Royal Society. 2016; A 374: 2067.

Claassen JA, Meel-Van Den Abeelen AS, Simpson DM, Panerai, RB, Dorado AC, Mitsis GD, Brassard P, Ainslie PN, Summers P, Iwasaki K, Ragauskas A, Tzeng YC, Müller M, Wang CY, Hu HH, Gommer E, Karemaker JM, Aries M, Van Lieshout JJ, Semenyuti V, Aliev V, Potter J, Smielewski P, Liu X, Czosnyka M, Payne S, Bailey D, Yelicich B, Puppo C, Shin D, Rickards CA, Serrador J, Zhang R, Marmarelis VZ, Novak V. Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network (CARNet). Journal of Cerebral Blood Flow and Metabolism. 2016; 36(4): 665 – 680.

Charalambides AC, Pontikis K, Mitsis GD, Dimitriadis G, Armaganidis A, Marmarelis VZ, Papavassilopoulos GP. Calibration of a Microdialysis Sensor and Recursive Glucose Level Estimation in ICU Patients Using Kalman and Particle Filtering. Biomedical Signal Processing and Control. 2016; 27: 155-163.

Vo TV, Das J, Meyer MJ, Cordero NA, Akturk N, Wei X, Fair BJ, Degatano AG, Fragoza R, Liu LG, Matsuyama A, Trickey M, Horibata S, Grimson A, Yamano H, Yoshida M, Roth FP, Pleiss JA, Xia Y, Yu H. A proteome-wide fission yeast interactome reveals network evolution principles from yeasts to human. Cell. 2016; 164: 310-323.

Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, GhamsariL, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M. Widespread expansion of protein interaction capabilities by alternative splicing. Cell. 2016; 164: 805-817.

Zhong Q, Pevzner SJ, Hao T, Wang Y, Mosca R, Menche J, Taipale M, Taşan M, Fan C, Yang X, Haley P, Murray RR, Mer F, Gebreab F, Tam S, MacWilliams A, Dricot A, Reichert P, Santhanam B, Ghamsari L, Calderwood MA, Rolland T, Charloteaux B, Lindquist S, Barabási AL, Hill DE, Aloy P, Cusick ME, Xia Y, Roth FP, Vidal M. An inter-species protein-protein interaction network across vast evolutionary distance. Molecular Systems Biology. 2016; 12: 865.

 

Other Refereed Work:

Hendricks AG, Goldman YE. Measuring molecular forces using calibrated optical tweezers
in living cells” Methods in Molecular Biology (2017) 537-552.

Munguia-Lopez J, Jiang T, Munoz-Sandoval E, De Leon-Rodriguez A, Kinsella JM. Carbon Nanotube-Alginate-Gelatin Hydrogel Composites as Bioprinting Inks. Tissue Engineering. 2016; Part A, 22: S145.

Jiang T, Munguia-Lopez J, Grant J, Vijayakumar S, Kinsella JM. Bioprintable Heterogenous Tumor Stroma In Vitro Model. Tissue Engineering. 2016; Part A, 22: S36

Samani SE, Amehdi N, Basu K, Kinsella JM. Multimodal theranostic polymersomes composed of hybrid inorganic nanoparticles. Frontiers in in Bioengineering and Biotechnology. doi: 10.3389/conf.FBIOE.2016.01.02837

Jiang T, Munguia-Lopez JG, Grant J, Vijayakumar S, Kinsella JM. Bioprinting heterogeneous 3D tumor models. Frontiers in in Bioengineering and Biotechnology. doi: 10.3389/conf.FBIOE.2016.01.00774

Malca M, Bao H, Kinsella JM, Friscic T, Moores A. Mechanochemical synthesis of bismuth sulfide nanoparticles for their use as contrast probes in computed tomography imaging. Frontiers in Bioengineering and Biotechnology. doi: 10.3389/conf.FBIOE.2016.01.02912

Conference proceedings:

Hendricks AG. Dissecting regulation by tubulin post-translational modifications, MAPs, and network architecture on microtubule-based transport. Gordon Research Conference Muscle and Molecular Motors: July 2016; Mount Snow, Vermont.

Heris HK, Khavari A, Hendricks AG, Ehrlicher AJ. Dissipation of stress in the cytoskeleton via actn4 dynamic crosslinking. Biophysical Society Meeting: February 2016; Los Angeles, California.

Balabanian L, Berger CL, Hendricks AG. The role of the microtubule cytoskeleton in regulating intracellular transport. Biophysical Society Meeting: February 2016; Los Angeles, California.

Manceur A, Marcil A, Zou W, Chen W, Gadoury C, Petiot E, Kamen A, Li X, Jaentschke B, Ansorge S. Pan-HA antibodies for influenza detection and quantification.Vaccine Technology: June 2016; Albufeira, Portugal.

Venereo-Sanchez A, Simoneau M, Caron A, Singh Chahal P, Jacob D, Leclerc M, Lytvyn V, Ansorge S, Gilbert R, Henry O, Kamen A. Characterization of HA and NA-containing VLPs produced in suspension cultures of HEK-293 cells.Vaccine Technology VI: June 2016; Albufeira, Portugal.

Kallel H, Trabelsi K, Ben Taleb C, Dhifali R, Kamen A. Evaluation of the immunogenicity of an adeno-associated virus vectored vaccine against hepatitis E virus. Vaccine Technology VI: June 2016; Albufeira, Portugal.

Venereo-Sanchez A, Simoneau M, Caron A, Singh Chahal P, Jacob D, Leclerc M, Lytvyn V, Ansorge S, Gilbert R, Henry O, Kamen A. Efficient production of influenza virus-like particles in HEK-293SF cells. Cell Culture Engineering XV: May 2016; Greater Palm Springs Area, California, USA

Shen CF, Chahal P, Gilbert R, Kostoglou K, Wright, AD, Smirl JD, Bryk, K, van Donkelaar P, Mitsis GD. Cerebral autoregulation in young athletes following concussion. 38th Ann. Intern. Conf. IEEE EMBS. August 2016; Orlando, Florida.

Prokopiou PC, Murphy K, Wise RG, Mitsis GD. Estimation of voxel-wise dynamic cerebrovascular reactivity curves from resting-state fMRI data. 38th Ann. Intern. Conf. IEEE EMBS: August 2016; Orlando, Florida.

Anastasiadou M, Hadjipapas A, Christodoulakis M, Papathanasiou E, Papacostas S, Mitsis GD. Epileptic Seizure Onset Correlates with Long Term EEG Functional Brain Network Properties. 38th Ann. Intern. Conf. IEEE EMBS: August 2016; Orlando, Florida.

Kostoglou K, Wright, AD, Smirl JD, Bryk, K, van Donkelaar P, Mitsis GD. Concussion and Cerebral Autoregulation in Young Athletes. 16th International Symposium on Intracranial Pressure and Neuromonitoring: June 2016; Boston Massachusetts.

Kostoglou K, Schondorf R, Benoit J, Balegh S, Mitsis GD. Prediction of the time to syncope occurrence in patients diagnosed with vasovagal syncope.” 16th International Symposium on Intracranial Pressure and Neuromonitoring: June 2016; Boston Massachusetts.

Nikolaou F, Orphanidou C, Papakyriakou P, Murphy K, Wise RG, Mitsis GD. Physiological Signals Modulate Dynamic Functional Connectivity in Resting-State fMRI. 22nd Annual Meeting of the Organization for Human Brain Mapping: June 2016; Geneva, Switzerland.

Kostoglou K, Wright AD, Smirl JD, Bryk K, van Donkelaar P, Mitsis GD. Cerebral autoregulation in young athletes following concussion. 38th Ann. Intern. Conf. IEEE EMBS: August 2016; Orlando Florida.

Prokopiou PC, Murphy K, Wise RG, Mitsis GD. Estimation of voxel-wise dynamic cerebrovascular reactivity curves from resting-state fMRI data. 38th Ann. Intern. Conf. IEEE EMBS: August 2016; Orlando Florida.

Anastasiadou M, Hadjipapas A, Christodoulakis M, Papathanasiou E, Papacostas S, Mitsis GD. Epileptic Seizure Onset Correlates with Long Term EEG Functional Brain Network Properties. 38th Ann. Intern. Conf. IEEE EMBS: August 2016; Orlando Florida.

Kostoglou K, Wright AD, Smirl JD, Bryk K, van Donkelaar P, Mitsis GD. Concussion and Cerebral Autoregulation in Young Athletes. 16th International Symposium on Intracranial Pressure and Neuromonitoring: June 2016; Boston Massachusetts.

Kostoglou K, Schondorf R, Benoit J, Balegh S, Mitsis GD. Prediction of the time to syncope occurrence in patients diagnosed with vasovagal syncope. 16th International Symposium on Intracranial Pressure and Neuromonitoring: June 2016; Boston Massachusetts.

Nikolaou F, Orphanidou C, Papakyriakou P, Murphy K, Wise RG, Mitsis GD. Physiological Signals Modulate Dynamic Functional Connectivity in Resting-State fMRI. 22nd Annual Meeting of the Organization for Human Brain Mapping: June 2016; Geneva, Switzerland.

Sharir-Ivry A, Xia Y. The impact of native state switching on protein sequence evolution at the residue level. 9th Annual GRASP Symposium: 2016.

Sharir-Ivry A, Xia Y. The impact of native state switching on protein sequence evolution at the residue level. Genome Evolution Conference: 2016.

Sharir-Ivry A, Xia Y. How protein structure multiplicity affects protein sequence evolution at the residue level. 23rd Jerusalem School in Life Sciences on: Computational and Structural Biology: 2016.

 

2015

Heine P, Ehrlicher AJ, Kaes J. Neuronal and metastatic cancer cells: unlike brothers. BBA - Molecular Cell Research. June 2015; 1853:3126-31. doi: 10.1016/j.bbamcr.2015.06.011.

Ehrlicher AJ, Krishnan R, Guo M, Bidan C, Weitz DA, Pollak MR. Alpha actinin binding kinetics modulate cellular dynamics and force generation. PNAS. 2015. doi: 10.1073/pnas.1505652112.

Kang J, Puskar K, Ehrlicher AJ, LeDuc P, Schwartz R. Structurally governed cell mechanotransduction through multiscale modeling. Scientific Reports. February 2015; 5:8622. doi:10.1038/srep08622.

Bender M, Thon J, Ehrlicher A, Wu S, Mazutis L, Deschmann E, Sola-Visner M, Italiano J, Hartwig J. Microtubule sliding drives proplatelet elongation and is dependent on cytoplasmic dynein. Blood. January 29; 125:860-868. doi:10.1182/blood-2014-09-600858.

Petiot E, Cuperlovic-Culf M, Shen CF, Kamen A. Influence of HEK293 metabolism on the production of viral vectors and vaccine. Vaccine. 2015; 33(44):5974-81. doi:10.1016/j.vaccine.2015.05.097.

Manceur AP, Kamen AA. Critical review of current and emerging quantification methods for the development of influenza vaccine candidates. Vaccine. 2015; 33(44):5913-9. doi:10.1016/j.vaccine.2015.07.104.

Emmerling VV, Pegel A, Milian EG, Venereo-Sanchez A, Kunz M, et al (Kamen A). Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells. Biotechnology Journal. 2015; doi:10.1002/biot.201500176.

Thompson CM, Petiot E, Mullick A, Aucoin MG, Henry O, Kamen AA. Critical assessment of influenza VLP production in Sf9 and HEK293 expression systems. BMC Biotechnology. 2015; 15:31. doi:10.1186/s12896-015-0152-x.

Kallel H, Kamen A. Large-scale adenovirus and poxvirus-vectored vaccine manufacturing to enable clinical trials. Biotechnology Journal. 2015; 10(5):741-7. doi:10.1002/biot.201400390.

Milian E, Kamen AA. Current and emerging cell culture manufacturing technologies for influenza vaccines. BioMed Res. Intern. 2015. doi:10.1155/2015/504831.

Transfiguracion J, Manceur AP, Petiot E, Thompson CM, Kamen AA. Particle quantification of influenza viruses by high performance liquid chromatography. Vaccine. 2015; 33(1):78-84. doi:10.1016/j.vaccine.2014.11.027.

Caron AL, Picanço-Castro V, Ansorge S, Covas DT, Kamen A, Swiech K. Production of lentiviral vectors encoding recombinant factor VIII expression in serum-free suspension cultures. Brazilian Archives of Biology and Technology. 2015; 58(6):923-928.

Loizides, C, Iacovides D, Hadjiandreou MM, Rizki G, Achilleos A, Strati K, Mitsis GD. Model-based tumor growth dynamics in a mouse model of de novo carcinogenesis. PLoS One. 2015; 10(12). doi:10.1371/journal.pone.0143840.

Charalambous E, Dikomitou-Eliadou P, Milis G, Mitsis GD, Eliades D. An experimental design for the classification of archaeological ceramic data from Cyprus, and the tracing of inter-class relationships. Journal of Archaeological Science: Reports. 2015. doi:10.1016/j.jasrep.2015.08.010.

Loizides CL, Achilleos AA, Iannetti GD, Mitsis GD. Assessment of nonlinear interactions in event-related potentials (ERPs) elicited by stimuli presented at short inter-stimulus intervals. Journal of Neurophysiology. 2015; 113:3623-3633.

Nguyen MT, Chaffee AL, Boysen RI, Nicolau DV, Hearn MTW. A versatile modelling approach to determine the hydrophobicity of peptides at the atomic level. Molecular Simulation. 2015; 45:257-269. doi:10.1080/08927022.2015.1038533.

Van Zalinge H, Ramsey LC, Aveyard J, Persson M, Mansson A, Nicolau DV. Surface-controlled properties of myosin studied by electric field modulation. Langmuir. 2015; 31(30):8354-8361. doi:10.1021/acs.langmuir.5b01549.

Hajne J, Hanson KL, van Zalinge H, Nicolau DV. Motility of actin filaments on micro-contact printed myosin patterns. IEEE Transactions on Nanobioscience, 2015; 14(3):313-322.

Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, Khurana V, Sharma A, Liu YY, Yachie N, Zhong Q, Shen Y, Palagi A, San-Miguel A, Fan C, Balcha D, Dricot A, Jordan DM, Walsh JM, Shah AA, Yang X, Stoyanova A, Leighton A, Calderwood MA, Jacob Y, Cusick ME, Salehi-Ashtiani K, Whitesell LJ, Sunyaev S, Berger B, Barabási AL, Charloteaux B, Hill DE, Hao T, Roth FP, Xia Y, Walhout AJM, Lindquist S, Vidal M. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 2015; 161(3):647-660. doi:10.1016/j.cell.2015.04.013.

Normandin MD, Yuan H, Wilks MQ, Chen HH, Kinsella JM, Cho H, Guehl NJ, Absi-Halabi N, Hosseini SM, El Fakhri G, Sosnovik DE, Josephson L. Heat-induced radiolabeling of nanoparticles for monocyte tracking by PET. Angewandte Chemie International Edition. 2015; 54(44):13002-13006. doi:10.1002/anie.201505525.

Normandin M, Yuan H, Wilks M, Kinsella J, El Fakhri G, Josephson L. Pharmacokinetic analysis of intravenously-injected 89Zr-labeled nanoparticles reveals monocyte trafficking. Journal of Nuclear Medicine. 2015; 56:652.

 

Book chapters:

Christodoulakis M, Hadjipapas A. Papathanasiou ES, Anastasiadou M, Papacostas SS, Mitsis GD. Modern Electroencephalographic Assessment Techniques. New York: Springer; 2015. On the effect of volume conduction on graph theoretic measures of brain networks in epilepsy; p. 103-130.

 

Other Refereed Work:

Zhang W, Dong X, Silva-Da Cruz S, Heris HK, Mongeau LG, Ehrlicher AJ, Liu X. A force-controlled, cost-effective microindentation system for soft material characterization. International Conference on Mechatronics and Automation. 2015; Beijing, China.

Apfel J, Parikh JR, Reischmann P, Ewing RM, Müller O, Xia Y, Dominguez I. The Wnt signaling network in cancer. Thiagalingam S, eds. Systems Biology of Cancer. 2015; 222-255.

 

Conference proceedings:

Iakovidou ND, Christodoulakis M, Papathanasiou ES, Papacostas SS, Mitsis GD. Introducing weighted approaches to study network brain dynamics from EEG epilepsy measurements: the EigenBrain algorithm. 15th IEEE International Biomedical Informatics and Bioengineering Conference (BIBE 2015): November 2015; Belgrade, Serbia.

Kostoglou K. Michmizos, KP, Stathis P, Sakas D, Nikita KS and Mitsis GD. Prediction of the outcome of Subthalamic Nucleus Deep Brain Stimulation in patients with Parkinson’s Disease. Biomedical Engineering Society Annual Meeting: October 2015; Tampa, Florida.

Anastasiadou M, Christodoulakis M, Papathanasiou ES, Papacostas SS, Mitsis GD. Automatic Detection and Removal of Muscle artifacts from Scalp EEG Recordings in Patients with Epilepsy. 37th Annual International Conference of the IEEE EMBS: 1946-1950, August 2015; Milano, Italy.

Papadopoulos A, Kostoglou K, Mitsis GD, Theocharides T. GPU technology as a platform for accelerating physiological systems modeling based on Laguerre-Volterra networks. 37th Annual International Conference of the IEEE EMBS: p. 3283-3286, August 2015; Milano, Italy.

Nikolaou F, Orphanidou C. Wise RG, Mitsis GD. Arterial CO2 Effects Modulate Dynamic Functional Connectivity in Resting-State fMRI. 37th Annual International Conference of the IEEE EMBS: 1809-1812, August 2015; Milano, Italy.

Kostoglou K, Poulin MJ, Mitsis GD. The time-dependent variability of arterial CO2 influences the nonstationary properties of dynamic CO2 reactivity estimates during resting conditions. 5th Annual Cerebral Autoregulation Network Meeting (CARNet): July 2015; Southampton, UK.

Clancy KFA, Nicolau DV. Protein patterning: A comparison of direct spotting versus microcontact printing. Progress in Biomedical Optics and Imaging - Proceedings of SPIE: 2015; 9328, 93280H.

Hajne J, Hanson KL, Van Zalinge H, Nicolau DV. Determination of the persistence length of actin filaments on micro-contact printed myosin patterns. Progress in Biomedical Optics and Imaging - Proceedings of SPIE: 2015; 9337, 93370G.

 

Non-Refereed Contributions:

Ehrlicher AJ, Ramaswamy K, Ming G, Bidan CM, Weitz DA, Pollak MR. Alpha Actinin Binding Kinetics Modulate Cellular Mechanics and Force Generation. Biomedical Engineering Society Proceedings: October 2015.

 

2014

Note: corresponding author; *student supervised by BIEN faculty member

Achilleos AA, Loizides CL,* Hadjiandreou M, Stylianopoulos T, Mitsis GD. Multiprocess linear dynamic modeling for individualized tumor growth prediction. Annals of Biomedical Engineering 42: 1095-1111 (2014).

Chakrabarty R, Tran H, Fortin Y, Yu Z, Shen SH, Kolman J, Onions D, Voyer R, Hagerman A, Serl S, Kamen A, Thompson B, Coffey M. Evaluation of homogeneity and genetic stability of REOLYSIN (pelareorep) by complete genome sequencing of reovirus after large scale production. Appl Microbiol Biotechnol 98: 1763-70 (2014).

Chahal PS, Schulze E, Tran R, Montes J, and Kamen AA. Production of adeno-associated virus (AAV) serotypes by transient transfection of HEK293 cell suspension cultures for gene delivery. J Virol Methods 196: 163-73 (2014).

Garamszegi S,* Yen JY, Honko AN, Geisbert JB, Robins KH, Geisbert TW, Xia Y, Hensley LE, Connor JH. Transcriptional correlates of disease outcome in anticoagulant-treated non-human primates infected with Ebolavirus. PLoS Neglected Tropical Diseases 8: e3061 (2014).

Gilbert R, Guilbault C, Gagnon D, Bernier A, Bourget L, Elahi SM, Kamen A, Massie B. Establishment and validation of new complementing cells for production of E1-deleted adenovirus vectors in serum-free suspension culture. J Virol Methods 208: 177-188 (2014).

Guo M, Ehrlicher AJ, Jensen MH, Renz M, Moore JR, Lippincott-Schwartz J, Mackintosh FC, Weitz DA. Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy. Cell 158: 822-832 (2014).

Hadjiandreou MM, Mitsis GD. Mathematical modeling of tumor growth, drug-resistance, toxicity, and optimal therapy design. IEEE Transactions on Biomedical Engineering 61: 415-425 (2014).

Hendricks AG, Goldman YE, Holzbaur ELF. Reconstituting the motility of isolated intracellular cargoes. Methods in Enzymology 540: 249-262 (2014).

Hu H,* Huang Y, Mao Y, Yu X, Xu Y, Liu J, Zong C, Boons GJ, Lin C, Xia Y, Zaia J. A computational framework for heparan sulfate sequencing using high-resolution tandem mass spectra. Molecular & Cellular Proteomics 13: 2490-2502 (2014).

Kostoglou K,* Debert CT, Poulin MJ, Mitsis GD. Nonstationary multivariate modeling of cerebral autoregulation during hypercapnia. Medical Engineering and Physics 36: 592-600 (2014).

Mahjoubi H, Kinsella JM, Murshed M, Cerruti M. Surface modification of poly(D,L-lactic acid) scaffolds for orthopedic applications: a biocompatible, non-destructive route via diazonium chemistry. ACS Applied Materials & Interfaces 6: 9975-9987 (2014).

Merten OW, Schweizer M, Chahal P, Kamen A. Manufacturing of viral vectors for gene therapy I: Upstream processing. Pharmaceutical Bioprocessing 2: 183-203 (2014).

Merten OW, Schweizer M, Chahal P, Kamen A. Manufacturing of viral vectors II: Downstream processing and safety aspects. Pharmaceutical Bioprocessing 2: 237-251 (2014).

Mitsis GD, Simpson DM. Special Issue on Cerebral Autoregulation: Measurement and modeling. Medical Engineering and Physics 36: 561-562 (2014).

Nicolau Jr. DV, Paszek E, Fulga F, Nicolau DV. Mapping hydrophobicity on the protein molecular surface at atom-level resolution. PLoS ONE: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114042 (2014).

Pandya C,* Dunaway-Mariano D, Xia Y, Allen KN. Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily. Proteins: Structure, Function, and Bioinformatics 82: 1896-1906 (2014).

Ramsey L, Schroeder V, van Zalinge H, Berndt M, Korten T, Diez S, Nicolau DV. Control and gating of kinesin-microtubule motility on electrically heated thermo-chips. Biomedical Microdevices 16: 459-463 (2014).

Rolland T, Tasan M, Charloteaux B, Pevzner SJ, Zhong Q, Sahni N, Yi S, Lemmens I, Fontanillo C, Mosca R, Kamburov A, Ghiassian SD, Yang X, Ghamsari L, Balcha D, Begg BE, Braun P, Brehme M, Broly MP, Carvunis AR, Convery-Zupan D, Corominas R, Coulombe-Huntington J, Dann E, Dreze M, Dricot A, Fan C, Franzosa E, Gebreab F, Gutierrez BJ, Hardy MF, Jin M, Kang S, Kiros R, Lin GN, Luck K, MacWilliams A, Menche J, Murray RR, Palagi A, Poulin MM, Rambout X, Rasla J, Reichert P, Romero V, Ruyssinck E, Sahalie JM, Scholz A, Shah AA, Sharma A, Shen Y, Spirohn K, Tam S, Tejeda AO, Trigg SA, Twizere JC, Vega K, Walsh J, Cusick ME, Xia Y, Barabasi AL, Iakoucheva LM, Aloy P, De Las Rivas J, Tavernier J, Calderwood MA, Hill DE, Hao T, Roth FP, Vidal M. A proteome-scale map of the human interactome network. Cell 159: 1212-1226 (2014).

Thon JN, Mazutis L, Wu S, Sylman JL, Ehrlicher A, Machlus KR, Feng Q, Lu S, Lanza R, Neeves KB, Weitz DA, Italiano JE Jr. Platelet bioreactor-on-a-chip. Blood (2014).

Trabelsi K, Kamen A, Kallel H. Development of a vectored vaccine against hepatitis E virus. Vaccine 32: 2808-11 (2014).

van den Abeelen ASSM, Simpson D, Zhang R, Tarumi T, Rickards CA, Payne SJ, Mitsis GD, Kostoglou K,* Marmarelis VZ, Shin D, Tzeng YC, Gommer E, Müller M, Caicedo Dorado A, Yelicich B, Puppo C, Liu X, Czosnyka M, Wang N, Novak V, Panerai RB, Claassen JAHR. Between-center variability in transfer function analysis: a widely used method for linear quantification of the dynamic pressure-flow relation: the CARnet bootstrap study. Medical Engineering and Physics 36: 620-627 (2014).

Xue R, Zakharov MN, Xia Y, Bhasin S, Costello JC, Jasuja R. EPSLiM: Ensemble predictor for short linear motifs in nuclear hormone receptors. Molecular Endocrinology 28: 768-777 (2014).

Yu C, Lopez CA, Hu H,* Xia Y, Freedman DS, Reddington AP, Daaboul GG, Unlu MS, Genco CA. A high-throughput method to examine protein-nucleotide interactions identifies targets of the bacterial transcriptional regulatory protein Fur. PLoS ONE 9: e96832 (2014).

 

Edited books and chapters in edited books:

Marmarelis VZ, Mitsis GD, eds. Data-driven modeling for Diabetes: Diagnosis and Treatment. Springer-Verlag, Heidelberg, Germany (2014).

Marmarelis VZ, Shin DC, Mitsis GD. Nonlinear Modeling of the Dynamic Effects of Free Fatty Acids on Insulin Sensitivity. In Data-driven Modeling for Diabetes Diagnosis and Treatment. Springer Lecture Notes in Bioengineering: 223-237 (2014).

Merten OW, Schweizer M, Chahal P, Kamen A. Chapter 26: Production and purification of viral vectors and safety considerations related to their use. Daniel Scherman, ed. Advanced textbook on gene transfer, gene therapy and genetic pharmacology: Principles, delivery and pharmacological and biomedical applications of nucleotide-based therapies, First Edition (Vol. 1): 493-515. Imperial College Press, London (2014).

Mitsis GD, Marmarelis VZ. Data-driven Modeling of Dynamic Insulin-Glucose Interactions: Comparison of Volterra Models with Compartmental Models and Application to Resting Insulin-Glucose Fluctuations in a Fasting Dog. In Data-driven Modeling for Diabetes Diagnosis and Treatment. Springer Lecture Notes in Bioengineering: 1-35 (2014).

Thompson CM, Aucoin MG, Kamen AA. Production of virus-like particles for vaccination. DW Murhammer, ed. Methods in molecular biology: Baculovirus and insect cell expression protocols, Third Edition: 1-10. Humana Press Inc., Totowa (2014).

Thompson CM, Montes J, Aucoin MG, Kamen AA. Recombinant protein production in large scale agitated bioreactors using the Baculovirus Expression Vector System. DW Murhammer, ed. Methods in molecular biology: Baculovirus and insect cell expression protocols, Third Edition: 1-10. Human Press (2014).

 

Conference proceedings:

Anastasiadou M,* Hadjipapas A, Christodoulakis M,* Papathanasiou E, Papacostas S, Mitsis GD. Detection and Removal of Muscle artifacts from Scalp EEG Recordings in Patients with Epilepsy. 14th IEEE International Biomedical Informatics and Bioengineering Conference (BIBE 2014): 291-296, Boca Raton FL (November 2014).

Christodoulakis M,* Hadjipapas A, Papathanasiou E, Anastasiadou M,* Papacostas S, Mitsis GD. Periodicity in functional brain networks: Application to scalp EEG from epilepsy patients. 36th Ann. Intern. Conf. IEEE EMBS: 2805-2808, Chicago IL (August 2014).

Christodoulakis M,* Papathanasiou E, Hadjipapas A, Anastasiadou M,* Papacostas S, Mitsis GD. Long-duration properties of functional brain networks in patients with epilepsy. 20th Annual Meeting of the Organization for Human Brain Mapping: Hamburg, Germany (June 2014).

Kostoglou K,* Debert CT, Poulin MJ, Mitsis GD. Nonstationary multivariate modeling of cerebral autoregulation during free-breathing and hypercapnic conditions. Proc 8th Conference of the European Study Group on Cardiovascular Oscillations: 193-194, Trento, Italy (May 2014).

Kostoglou K,* Debert CT, Poulin MJ, Mitsis GD. Multivariate nonstationary modeling of cerebral hemodynamics. 36th Ann. Intern. Conf. IEEE EMBS: 6028-6031, Chicago IL (August 2014; invited).

Kostoglou K,* Hadjipapas A, Lowet E, Roberts MJ, De Weerd P, Mitsis GD. Accurate spike time prediction from LFP in monkey visual cortex: a nonlinear system identification approach. 9th Forum of the Federation of European Neuroscience Societies (FENS): Milan, Italy (July 2014).

Loizides C,* Achilleos A, Iannetti GD, Mitsis GD. Assessment of nonlinear interactions in event-related potentials (ERPs) elicited by stimuli presented at short inter-stimulus intervals. 20th Annual Meeting of the Organization for Human Brain Mapping: Hamburg, Germany (June 2014).

Loizides C,* Achilleos A, Iannetti GD, Mitsis GD. A mixed effects model framework for the assessment of nonlinear interactions in event-related potentials (ERPs) elicited by identical successive stimuli. 36th Ann. Intern. Conf. IEEE EMBS: 4543-4546, Chicago IL (August 2014).

Prokopiou PC,* Pattinson KTS, Wise RG, Mitsis GD. Regional variability of the brain hemodynamic response to spontaneous and step-induced CO2 changes. 20th Annual Meeting of the Organization for Human Brain Mapping: Hamburg, Germany (June 2014).