Georgios D. Mitsis

Associate Professor
Undergraduate Program Director

Ph.D. University of Southern California, Los Angeles
M.S. (EE) University of Southern California, Los Angeles
M.S. (BME) University of Southern California, Los Angeles
Diploma National Technical University of Athens, Athens, Greece

McConnell Engineering Building, Room 361


Research Interests

  • Identification/ modeling of nonlinear and nonstationary systems
  • Biomedical signal and image processing
  • Mathematical modeling of biological systems
  • Quantitative/ systems physiology
  • Cerebral hemodynamics and blood flow autoregulation
  • Functional neuroimaging and resting-state network analysis
  • Glucose metabolism and control
  • Computational oncology: mathematical modeling of tumor growth and optimal therapy design


  • BIEN 350: Biosystems and Control (3 credits)
  • BIEN 462: Engineering Principles in Physiological Systems (3 credits)
  • BIEN 470: Bioengineering Design Project (6 credits)

Selected Publications

Nonstationary multivariate modeling of cerebral autoregulation during hypercapnia
Kostoglou K., Debert C.T., Poulin M.J., Mitsis G.D. Medical Engineering and Physics (published online December 2013)

Controlling cancer progression in mice: Mathematical modeling and optimal control
Hadjiandreou M.M., Mitsis, G.D. , IEEE Transactions on Biomedical Engineering (published online September 2013, 10.1109/TBME.2013.2280189)

Nonlinear Modeling of Glucose Metabolism: Comparison of Compartmental with Volterra models
Mitsis, G.D., Markakis, M.G., Marmarelis, V.Z., IEEE Transactions on Biomedical Engineering 56: 2347-2358, 2009

Visit MEDLINE indexed publications for more.