Dan Nicolau

Dan NicolauMarika Zelenka Roy Chair in Bioengineering
Professor

Ph.D. Polytechnical University at Bucharest, Romania
M.S. Academy of Economic Studies at Bucharest, Romania

McConnell Engineering Building, Room 353

514.398.8261
chair.bioeng [at] mcgill.ca (e-mail )
website


Research Interests

  • design and fabricate dynamic hybrid nanodevices comprising linear protein molecular motors working on semiconductor manufactured electro-mechanical devices;
  • design and fabricate ‘smart’ micro/nano-profiled and electrically-active surfaces that combinatorially probe the response of biomolecules for micro/nano-array applications;
  • study effective, non-denaturating technologies for immobilization of biomolecules in static (e.g. biosensors) and dynamic (e.g. microfluidics) biodevices;
  • study intelligent-like behaviour and algorithms used by microorganisms in their survival and search strategies, probed in microfabricated structures

Courses

  • BIEN 200: Introduction to Bioengineering (2 credits)
  • BIEN 520: High Throughput Bioanalytical Devices (3 credits)

Selected Publications

Polymer surfaces properties control the function of heavy meromyosin in dynamic nanodevices.
Hanson, K.L., Fulga, F., Dobroiu, S., Solana, G., Kaspar, O., Tokarova, V., Nicolau, D.V.
Biosensors & Bioelectronics. 2017; 93, 305-314. DOI: 10.1016/j.bios.2016.08.061

Parallel computation with molecular-motor-propelled agents in nanofabricated networks.
Nicolau, Jr. D.V., Lard, M., Korten, T. , van Delft, F.C.M.J.M., Persson, M. Bengtsson, E., Månsson, A., Diez, S. Linke, H., Nicolau, D.V.
Proc. Natl. Acad. Sci. U.S.A. 2016; 113(10), 2591-25. DOI: 10.1073/pnas.1510825113

Confinement of water droplets on rectangular micro/nano-arrayed surfaces.
Kašpar, O., Zhang, H., Tokárová, V., Boysen, R.I., Suñé, G.R., Borrise, X., Perez-Murano, F., Hearn, M.T.W., Nicolau, D.V.*
Lab on a Chip. 2016; 16(13), 2487-2493. DOI: 10.1039/c6lc00622a

Visit MEDLINE indexed publications for more.