Amine A. Kamen

Professor

Canada Research Chair in Bioprocessing of Viral Vaccines

National Research Council of Canada Research Emeritus

Ph.D. Ecole Polytechnique de Montreal;
Doct.-Ing. Ecole des Mines de Paris

McConnell Engineering Building, Room 363

514.398.5775
amine.kamen [at] mcgill.ca (e-mail)
website

Research Interests

• Cell Culture Engineering
• Bioprocess Optimization and Scale-up
• Process Analytical Technologies and Process Control
• Viral Vaccines Manufacturing
• Viral Vectors and Nanoparticules for Gene Delivery and Vaccination

Courses

BIEN 340: Transport Phenomena in Biological Systems 2

BIEN 590: Cell Culture Engineering

BIEN 680: Bioprocessing of Vaccines

Selected Publications

Serum-free production of rVSV-ZEBOV in Vero cells: Microcarrier bioreactor versus scale-X™ hydro fixed-bed.
Kiesslich S, Vila-Chã Losa JP, Gélinas JF, Kamen AA.  J Biotechnol. 2020 Feb 20;310:32-39. doi: 10.1016/j.jbiotec.2020.01.015. Epub 2020 Jan 30.
PubMed PMID: 32006630.

Lentiviral Vector Production in Suspension Culture Using Serum-Free Medium for the Transduction of CAR-T Cells.
Do Minh A, Tran MY, Kamen AA.  Methods Mol Biol. 2020;2086:77-83. doi: 10.1007/978-1-0716-0146-4_6. 
PubMed PMID: 31707669.

Adeno-Associated Viral Vectors for Homology-Directed Generation of CAR-T Cells.
Moço PD, Aharony N, Kamen A. Biotechnol J. 2020 Jan;15(1):e1900286. doi: 10.1002/biot.201900286. Epub 2019 Nov 19. Review. 
PubMed PMID: 31642193.

Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF.
Vaccine.Venereo-Sánchez A, Fulton K, Koczka K, Twine S, Chahal P, Ansorge S, Gilbert R, Henry O, Kamen A.  2019 Nov 8;37(47):7100-7107. doi: 10.1016/j.vaccine.2019.07.057. 
Epub 2019 Jul 26. PubMed PMID: 31358407.

Development of suspension adapted Vero cell culture process technology for production of viral vaccines.
Shen CF, Guilbault C, Li X, Elahi SM, Ansorge S, Kamen A, Gilbert R.  Vaccine. 2019 Nov 8;37(47):6996-7002. doi: 10.1016/j.vaccine.2019.07.003. 
Epub 2019 Jul 6. PubMed PMID: 31288997.

Please see NCBI for a more comprehensive listing.