Amine A. Kamen

Professor

Canada Research Chair in Bioprocessing of Viral Vaccines

National Research Council of Canada Research Emeritus

Ph.D. Ecole Polytechnique de Montreal;
Doct.-Ing. Ecole des Mines de Paris

McConnell Engineering Building, Room 363

514.398.5775
amine.kamen [at] mcgill.ca (e-mail)
website


Research Interests

  • Cell Culture Engineering
  • Bioprocess Optimization and Scale-up
  • Process Analytical Technologies and Process Control
  • Viral Vaccines Manufacturing
  • Viral Vectors and Nanoparticules for Gene Delivery and Vaccination

Courses

BIEN 340: Transport Processes in Biological Systems (3 credits)

Selected Publications

Gene Transfer of ZMapp Antibodies Mediated by Recombinant Adeno-Associated Virus Protects Against Ebola Infections.
Robert MA, Nassoury N, Chahal PS, Venne MH, Racine T, Qiu X, Kobinger G, Kamen A, Gilbert R, Gaillet B.
Hum Gene Ther. 2018 Apr;29(4):452-466. doi: 10.1089/hum.2017.101. Epub 2018 Mar 1.
PMID: 29179602

Advancements in the design and scalable production of viral gene transfer vectors. 
Sharon D, Kamen A.
Biotechnology and Bioengineering. 2018; 115(1):25-40. doi:10.1002/bit.26461
PMID: 28941274

Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line.
Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal P, Bourget L, Ansorge S, Gilbert R, Henry O, Kamen A.
Vaccine. 2017 Jul 24;35(33):4220-4228. doi: 10.1016/j.vaccine.2017.06.024. Epub 2017 Jun 22.
PMID: 28648546

Accelerated mass production of influenza virus seed stocks in HEK-293 suspension cell cultures by reverse genetics. 
Milián E, Julien T, Biaggio R, Venereo-Sanchez A, Montes J, Manceur AP, Ansorge  S, Petiot E, Rosa-Calatrava M, Kamen A. 
Vaccine. 2017; 35(26):3423-3430. doi: 10.1016/j.vaccine.2017.04.065
 PMID: 28495315

RNA interference technology to improve the baculovirus-insect cell expression system.
Chavez-Pena C, Kamen AA.
Biotechnol Adv. 2018 Mar - Apr;36(2):443-451. doi: 10.1016/j.biotechadv.2018.01.008. Epub 2018 Feb 1. Review.
PMID: 29395442

Please see NCBI for a more comprehensive listing.