Professor
ProfessorCanada Research Chair in Bioprocessing of Viral Vaccines
National Research Council of Canada Research Emeritus
Ph.D. Ecole Polytechnique de Montreal;
Doct.-Ing. Ecole des Mines de Paris
McConnell Engineering Building, Room 363
514.398.5775
amine.kamen [at] mcgill.ca (e-mail)
website
Research Interests
- Cell Culture Engineering
- Bioprocess Optimization and Scale-up
- Process Analytical Technologies and Process Control
- Viral Vaccines Manufacturing
- Viral Vectors and Nanoparticules for Gene Delivery and Vaccination
Courses
BIEN 340: Transport Processes in Biological Systems (3 credits)
BIEN 590: Cell Culture Engineering
BIEN 680: Bioprocessing of Vaccines
Selected Publications
Gene Transfer of ZMapp Antibodies Mediated by Recombinant Adeno-Associated Virus Protects Against Ebola Infections.
Robert MA, Nassoury N, Chahal PS, Venne MH, Racine T, Qiu X, Kobinger G, Kamen A, Gilbert R, Gaillet B.
Hum Gene Ther. 2018 Apr;29(4):452-466. doi: 10.1089/hum.2017.101. Epub 2018 Mar 1.
PMID: 29179602
Advancements in the design and scalable production of viral gene transfer vectors.
Sharon D, Kamen A.
Biotechnology and Bioengineering. 2018; 115(1):25-40. doi:10.1002/bit.26461
PMID: 28941274
Process intensification for high yield production of influenza H1N1 Gag virus-like particles using an inducible HEK-293 stable cell line.
Venereo-Sanchez A, Simoneau M, Lanthier S, Chahal P, Bourget L, Ansorge S, Gilbert R, Henry O, Kamen A.
Vaccine. 2017 Jul 24;35(33):4220-4228. doi: 10.1016/j.vaccine.2017.06.024. Epub 2017 Jun 22.
PMID: 28648546
Accelerated mass production of influenza virus seed stocks in HEK-293 suspension cell cultures by reverse genetics.
Milián E, Julien T, Biaggio R, Venereo-Sanchez A, Montes J, Manceur AP, Ansorge S, Petiot E, Rosa-Calatrava M, Kamen A.
Vaccine. 2017; 35(26):3423-3430. doi: 10.1016/j.vaccine.2017.04.065
PMID: 28495315
RNA interference technology to improve the baculovirus-insect cell expression system.
Chavez-Pena C, Kamen AA.
Biotechnol Adv. 2018 Mar - Apr;36(2):443-451. doi: 10.1016/j.biotechadv.2018.01.008. Epub 2018 Feb 1. Review.
PMID: 29395442
Please see NCBI for a more comprehensive listing.