Dan Nicolau

Dan NicolauMarika Zelenka Roy Chair in Bioengineering

Ph.D. Polytechnical University at Bucharest, Romania
M.S. Academy of Economic Studies at Bucharest, Romania

McConnell Engineering Building, Room 353

chair.bioeng [at] mcgill.ca (e-mail )

Research Interests

  • design and fabricate dynamic hybrid nanodevices comprising linear protein molecular motors working on semiconductor manufactured electro-mechanical devices;
  • design and fabricate ‘smart’ micro/nano-profiled and electrically-active surfaces that combinatorially probe the response of biomolecules for micro/nano-array applications;
  • study effective, non-denaturating technologies for immobilization of biomolecules in static (e.g. biosensors) and dynamic (e.g. microfluidics) biodevices;
  • study intelligent-like behaviour and algorithms used by microorganisms in their survival and search strategies, probed in microfabricated structures


  • BIEN 200: Introduction to Bioengineering
  • BIEN 420: Biodevices Design for Diagnostics and Screening
  • BIEN 540: Information Storage and Processing in Biological Systems

Selected Publications

Polymer surfaces properties control the function of heavy meromyosin in dynamic nanodevices.
Hanson, K.L., Fulga, F., Dobroiu, S., Solana, G., Kaspar, O., Tokarova, V., Nicolau, D.V.
Biosensors & Bioelectronics. 2017; 93, 305-314. DOI: 10.1016/j.bios.2016.08.061

Parallel computation with molecular-motor-propelled agents in nanofabricated networks.
Nicolau, Jr. D.V., Lard, M., Korten, T. , van Delft, F.C.M.J.M., Persson, M. Bengtsson, E., Månsson, A., Diez, S. Linke, H., Nicolau, D.V.
Proc. Natl. Acad. Sci. U.S.A. 2016; 113(10), 2591-25. DOI: 10.1073/pnas.1510825113

Confinement of water droplets on rectangular micro/nano-arrayed surfaces.
Kašpar, O., Zhang, H., Tokárová, V., Boysen, R.I., Suñé, G.R., Borrise, X., Perez-Murano, F., Hearn, M.T.W., Nicolau, D.V.*
Lab on a Chip. 2016; 16(13), 2487-2493. DOI: 10.1039/c6lc00622a

Visit MEDLINE indexed publications for more.

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