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Jasmin Coulombe-Huntington

Academic title(s): 

Faculty Lecturer

Jasmin Coulombe-Huntington
Contact Information
Email address: 
jasmin.coulombe-huntington [at] mcgill.ca
Office: 
Macdonald Engineering Building room 483 (MD483)
Degree(s): 

Ph.D., Bioinformatics, Boston University

M.Sc., Human Genetics, McGill University

B.Sc., Biochemistry, McGill University

Areas of interest: 
  • Machine learning, data mining, large-scale data integration and web resources
  • Genome-wide CRISPR screens
  • Bioinformatics algorithm design
  • Systems biology
  • Network-based modelling
  • Comparative genomics and proteomics
  • Short linear interaction motif prediction
  • Mapping and predicting gene functions and protein interactions
  • Epigenetics, transcriptional regulation and alternative splicing
  • Omics-based diagnostics and prevention
  • Plasma DNA sequencing
  • Mass spectrometry-based proteomics and metabolomics
  • Drug repurposing
  • Influence of diet and environment on health
Selected publications: 

Bertomeu T*, Coulombe-Huntington J*, Chatr-aryamontri A, Bourdages K, Coyaud E, Raught B, Xia Y, Tyers M. 2018. A High-Resolution Genome-Wide CRISPR/Cas9 Viability Screen Reveals Structural Features and Contextual Diversity of the Human Cell-Essential Proteome. Molecular Cell Biology

Coulombe-Huntington J, Xia Y. 2017. Network Centrality Analysis in Fungi Reveals Complex Regulation of Lost and Gained Genes. PLoS ONE

Yang X*, Coulombe-Huntington J*, Kang S*, Sheynkman GM, Hao T, ...,Xia Y, Vidal M.. 2016. Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing. Cell

Sahni N*, Yi S*, Taipale M*, Fuxman Bass JI*, Coulombe-Huntington J*, ..., Roth FP, Xia Y, Walhout AJM, Lindquist S , Vidal M. 2015. Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders. Cell

Coulombe-Huntington J, Xia Y. (2012), Regulatory Network Structure as a Dominant Determinant of Transcription Factor Evolutionary Rate. PLoS Computational Biology

Coulombe-Huntington J, Lam K, Dias C, Majewski J. 2009. Fine-Scale Variation and Genetic Determinants of Alternative Splicing across Individuals. PLoS Genetics.

Coulombe-Huntington J, Majewski J. 2007. Intron loss and gain in Drosophila. Molecular Biology and Evolution

Coulombe-Huntington J, Majewski J. 2007. Characterization of intron loss events in mammals. Genome Research *equal contribution

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