Dan Nicolau
Professor
Marika Zelenka Roy Chair in Bioengineering
Ph.D. Polytechnical University at Bucharest, Romania
M.S. Academy of Economic Studies at Bucharest, Romania
- design and fabricate dynamic hybrid nanodevices comprising linear protein molecular motors working on semiconductor manufactured electro-mechanical devices;
- design and fabricate ‘smart’ micro/nano-profiled and electrically-active surfaces that combinatorially probe the response of biomolecules for micro/nano-array applications;
- study effective, non-denaturating technologies for immobilization of biomolecules in static (e.g. biosensors) and dynamic (e.g. microfluidics) biodevices;
- study intelligent-like behaviour and algorithms used by microorganisms in their survival and search strategies, probed in microfabricated structures
Polymer surfaces properties control the function of heavy meromyosin in dynamic nanodevices.
Hanson, K.L., Fulga, F., Dobroiu, S., Solana, G., Kaspar, O., Tokarova, V., Nicolau, D.V.
Biosensors & Bioelectronics. 2017; 93, 305-314. DOI: 10.1016/j.bios.2016.08.061
Parallel computation with molecular-motor-propelled agents in nanofabricated networks.
Nicolau, Jr. D.V., Lard, M., Korten, T. , van Delft, F.C.M.J.M., Persson, M. Bengtsson, E., Månsson, A., Diez, S. Linke, H., Nicolau, D.V.
Proc. Natl. Acad. Sci. U.S.A. 2016; 113(10), 2591-25. DOI: 10.1073/pnas.1510825113
Confinement of water droplets on rectangular micro/nano-arrayed surfaces.
Kašpar, O., Zhang, H., Tokárová, V., Boysen, R.I., Suñé, G.R., Borrise, X., Perez-Murano, F., Hearn, M.T.W., Nicolau, D.V.*
Lab on a Chip. 2016; 16(13), 2487-2493. DOI: 10.1039/c6lc00622a