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DESCRIPTION:\nThe Feindel Brain Imaging Lecture Series\n\n\n	'Network Modeli
 ng with Biologically-Based Cellular Models'\n\n	Monday\, November 23\, 2015
  at 1:00 pm\n		de Grandpré Communications Centre\, Montreal Neurological Ins
 titute\n\n	\n		\n\n		Dr. Frances K Skinner\n			(Toronto Western Research Institute
 \, University Health Network\, University of Toronto)\n\n		 \n\n		Abstract:\n			D
 ue to its complex dynamics and multi-scale structure\, it is an extreme ch
 allenge to figure out how our brains work.  Experiments alone cannot provi
 de an understanding – modeling and computation are essential.  Given the h
 igh degree of technical expertise required in experimentation\, modeling\,
  computation and analyses\, it is clear that to move forth in our understa
 nding\, open and interactive collaborations between several individuals an
 d disciplines are needed.\n\n		Oscillatory activities are produced by severa
 l brain structures\, including the hippocampus\, and have been shown to be
  important for brain functioning.  The hippocampus is a heavily studied br
 ain structure due to its importance in learning and memory\, as well as be
 ing associated with disease states such as epilepsy and Alzheimer’s diseas
 e.  In this talk\, I will present some of the modeling work being done in 
 my group to understand the essential features and mechanisms for the gener
 ation of rhythmic output in microcircuits of the hippocampus.  Through col
 laborative efforts\, we have developed and are developing cellular and net
 work models with tight experimental linkages\, and in which theoretical in
 sights and constraints can be brought to bear.  We are using them to help 
 identify critical cellular and synaptic ‘balances’ that underlie populatio
 n output.  In this way\, we aim to use our models to not only understand n
 ormal brain functioning but also diseased states when these balances go aw
 ry.\n\n		 \n\n		Brief Bio:\n			Frances Skinner studied Applied Mathematics and Co
 mputer Science at the University of Waterloo (B.Math) and then did graduat
 e studies at the University of Toronto in Biomedical Engineering (M.A.Sc.\
 , Ph.D.).  She got involved in the world of Neuroscience during postdoctor
 al studies in Boston and California\, and has been part of the burgeoning 
 field of Computational Neuroscience ever since.  She is interested in dete
 rmining neuronal and network mechanisms that contribute to brain functioni
 ng during normal and diseased states.  To this end\, the research in her l
 ab focuses on mathematical model development and usage at the interface of
  theory\, computation\, and experiment.\n\n		 \n	\n\n	\n		\n		Unless specified oth
 erwise\, lectures are held on Mondays at 1:00 pm in the de Grandpré Commun
 ications Centre of the Montreal Neurological Institute.  \n\n		To be notifie
 d about these lectures and all the other events going on at the BIC\, plea
 se join the BIC-Announcements Mailing List.  For more information\, please
  contact Zografos Caramanos.\n	\n\n	 \n\n\n \n
DTSTART:20151123T180000Z
DTEND:20151123T190000Z
LOCATION:de Grandpré Communications Centre\, CA\, H3A 2B4\, Montreal Neurol
 ogical Institute and Hospital\, 3801 University Street
SUMMARY:[Feindel Brain Imaging Lecture] Network Modeling with Biologically-
 Based Cellular Models - Dr. Frances K Skinner
URL:https://www.mcgill.ca/bic/channels/event/feindel-brain-imaging-lecture-
 network-modeling-biologically-based-cellular-models-dr-frances-k-255291
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