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Kathryn Gill, PhD

Kathryn Gill, PhD

Kathryn Gill is the Director of Research at the Addictions Unit of the McGill University Hospital Centre (MUHC), and an Associate Professor in the Psychiatry Department at McGill University. She obtained her Ph.D (1990) in psychology, and conducted post-doctoral studies at the Alcohol Research Centre, and the Addiction Research and Treatment Services of the University of Colorado. She currently holds a Chercheur-Boursier career award from FRSQ (Quebec), and divides her time between teaching at McGill University and conducting research at the Addictions Unit and the Research Institute of the MUHC.
Dr Gill's research program has been focussed on mental illness and substance dependence; with projects completed in diverse areas including transcultural psychiatry, psychiatric comorbidity and treatment outcome. Her clinical research program is comprised of the following projects:

  • mental health problems and substance abuse among Aboriginal peoples: relationship to early life trauma, physical and sexual abuse, associated psychopathology and barriers to treatment;
  • substance abuse and schizophrenia: the impact of dual diagnosis on the quality of care for the chronically mentally ill;
  • clinical studies on the treatment of substance abuse: clinical and biological predictors of outcome and the development of new psychological and pharmacological therapies.

Her basic research program is focused on examining biological and genetic factors that contribute to the development of addiction and mental illness. These projects include biochemical, behavioural and genetic studies on the pharmacological response to drugs of abuse, as well as an examination of serotonin synthesis in alcohol abusers using positron emission tomography (PET).

kathryn [dot] gill [at] mcgill [dot] ca (email)

Selected Publications

Boyle, A.E.L., Gill, K. (2001). Sensitivity of AXB/BXA recombinant inbred lines of mice to the locomotor activating effects of cocaine: A QTL analysis. Pharmacogenetics, 11, 255-264.

Charney, D., Palacios-Boix, J., Negrete, J.C., Dobkin, P.I., Gill, K. (2005) The effects of concurrent depression and anxiety on addiction treatment outcome. Psychiatric Services, 56(8), 927-33.

Charney, D., Paraherakis, A., Gill, K. (2000). The treatment of sedative-hypnotic dependence: evaluating clinical predictors of outcome. Journal of Clinical Psychiatry, 61, 190-195.

Charney, D., Paraherakis, A., Gill, K. (2001). Integrated treatment of comorbid depression and substance use disorders. Journal of Clinical Psychiatry, 62, 672-677.

Dobkin, P., De Civita, M., Paraherakis, A., Gill, K. (2002). The role of social support in treatment retention and outcomes among outpatient adult substance abusers. Addiction, 97, 347-356.

Gill, K., Boyle AEL. (2003). Confirmation of quantitative trait loci for cocaine-induced activation in the AcB/BcA series of recombinant congenic strains. Pharmacogenetics, 13, 329-338.

Gill K., Boyle AEL. (2005) Genetic factors influencing sensitivity to nicotine: A QTL analysis in AcB/BcA recombinant congenic mice. Genes, Brain and Behavior, 4, 401-411.

Gill K., Boyle AEL. (2005) Genetic analysis of alcohol intake in recombinant inbred and congenic strains derived from A/J and C57BL/6J progenitors. Mammalian Genome, 16, 319-31.

Gill K., Boyle AEL. (2005) Quantitative trait loci for an anxiety-related trait in recombinant inbred (RI) and recombinant congenic (RC) strains of mice. Behavioral Brain Research, 161(1), 113-24.

Gill, K., Boyle, A., Lake, K., Desaulniers, N. (2000). Alcohol-induced locomotor activation in C57BL/6J, A/J, and AXB/BXA recombinant inbred mice: strain distribution patterns and quantitative trait loci. Psychopharmacology, 150, 412-421.

Gooderham, P.A., Gagnon R.F., Gill, K. (2004). Attenuation of alcohol preference in C57BL/6J mice during chronic renal failure. Journal of Laboratory and Clinical Medicine, 143, 292-300.

Igartua, K., Gill K., Montoro, R. (2003) Internalised homophobia: a factor in depression, anxiety and suicide in the gay and lesbian population. Canadian Journal of Community Mental Health, 22, 15-30.

Jacobs, K., Gill, K. (2002). Substance abuse among urban Aboriginals: Association with a history of physical/sexual abuse, Journal of Ethnicity in Substance Abuse, 1(2), 19-39.

Jacobs, K., Gill, K. (2002). Substance abuse in an urban Aboriginal population: Social, legal and psychological consequences, Journal of Ethnicity in Substance Abuse, 1(1), 7-25.

Margolese, H., Malchy, L., Tempier, R., Negrete J.C., Gill, K. (2004). Drug and alcohol use among patients with schizophrenia and schizoaffective disorder: Levels and consequences. Schizophrenia Research, 67, 157-166.

Margolese, HL, Tempier,R, Negrete JC, Gill K. (2006) Drug and alcohol use among patients with schizophrenia: results of a one-year followup. Schizophrenia Research, [in press].

Paraherakis, A., Charney, D., Gill, K. (2001). Neuropsychological functioning in substance dependent patients. Substance Use and Misuse, 36 (3), 257-271.

Paraherakis, A., Charney, D., Palacios-Boix, J., Gill, K. (2000). An abstinence-oriented program for substance use disorders: Poorer outcomes associated with opiate dependence. Canadian Journal of Psychiatry, 45, 927-931.