TB Centre Research Day 2017

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Welcome to the McGill International Tuberculosis Centre         

World TB Day at McGill 

March 24, 2018

This year's theme: "Wanted: Leaders for a TB-Free world" reminds us that all can be leaders of efforts to end TB in their own work or terrain.
See how you can make a difference

March 24th marks World TB Day. Tuberculosis (TB) is curable and preventable but continues to kill worldwide. According to the World Health Organization (WHO), there are more than 10 million of TB cases and 1.8 million deaths every year. For many years in Montreal, top research leaders have been working together under the umbrella of the McGill International TB Centre to better understand, diagnose and treat TB and other mycobacterial diseases.  

Tuberculosis is caused by the bacteria Mycobacterium tuberculosis that most often affects the lungs. The infection spreads from person to person through the air. When someone develops active TB, the symptoms (cough, fever, night sweats, weight loss etc.) may be mild or nonexistent for many weeks. This can lead to delays in seeking care, and that can result in transmission of the bacteria to others. Without proper treatment, up to two thirds of people with TB will die.



MORE ON THE GLOBAL FIGHT AGAINST TB

The Government of Canada and Inuit Tapiriit Kanatami commit to eliminating tuberculosis across Inuit Nunangat by 2030 - Active TB cases to be reduced by at least 50% by 2025

World TB Day 2018: Wanted: Leaders for a TB-free world - WHO Page

Stop TB Partnership World TB Day 2018

World TB Day 2017 Events Around the World


 

 

 

TB-oriented and other courses at the McGill Summer Institute in Infectious Diseases and Global Health

Registration now Open


Re-programming innate immune cells to fight tuberculosis

Canadian researchers’ innovative work promises to make vaccines more effective against tuberculosis and other infectious diseases like the flu. 

"We can harness the power of stem cells in vaccine against TB". Through a fantastic collaboration between Dr. Divangahi and Dr. Barreiro's Lab, they showed that BCG reprogramming of stem cells generates trained immunity against TB.

"BCG educates hematopoietic stem cells to generate protective innate immunity against tuberculosis,"  Jan. 11, 2018, in Cell. DOI: 10.1016/j.cell.2017.12.031 For more info

See the French Video from Radio Canada


Congratulations to Dr. Madhukar Pai and his team, awarded support from Grand Challenges Canada for pioneering work to improve the diagnosis of TB in children under the age of 15. Grand Challenges Canada named the team as one of the top 20 Canadian ideas to improve maternal and child health.


Congratulations to TB Centre trainees Jean-Yves Dube (Behr group), Jeffrey Downey (Divangahi group) and Madlen Nash (Pai Group) who were awarded RI MUHC Studentships or Fellowships for 2018!

 McGill Research influences WHO TB policies

WHO has just released new clinical guidelines for treatment of INH-resistant TB (based in part on the work of Dr Dick Menzies and others at McGill, Montreal). Isoniazid-resistant TB, without concurrent rifampicin resistance, is estimated to occur in about 8% of people with TB globally. A regimen of 6 months rifampicin, ethambutol, pyrazinamide and levofloxacin is now recommended in adults and children diagnosed with this type of drug-resistant TB. Resistance to rifampin and fluoroquinolones should be ruled out before using this regimen.
Read more


 

Introducing N-TB, an app for nutritional assessment & counselling of patients with tuberculosis

On World TB Day, the Center for Nutrition Studies, Yenepoya University, Mangalore in association with McGill International TB Centre, Montreal will announce the public release of N-TB, an android mobile based application for the nutritional assessment and counseling of adult patients with TB. This app, endorsed by the Revised National Tuberculosis Control Programme and WHO India, was included in the new initiatives unveiled by Prime Minister Narendra Modi during the Delhi End TB Summit held in March. Download the App for free on Google Play


Great job at knowledge synthesis by TB Centre researchers:

Nature Review Primer on TB.

Just got designated as a ‘Highly cited paper’ by the Web of Science, meaning it is among the top 1% of papers of similar age in the field of clinical medicine! Read it here: http://go.nature.com/2Da2w2q 


The top-cited systematic reviews/meta-analyses in tuberculosis research:

McGill authors topped the rankings as first and corresponding authors in systematic reviews and meta-analyses in TB research.


The 100 top-cited tuberculosis research studies

According to a study, McGill researchers account for 6% of the world's best cited TB papers which is very high ranking! The 100 top-cited tuberculosis research https://www.atsjournals.org/doi/10.1164/rccm.201707-1489PPstudies (International Union Against Tuberculosis and Lung Disease) Download


Post Doctoral Fellowship Positions in Tuberculosis Research Available:


Recent TB Articles/Publications

Our centre brings together over 20 investigators with expertise spanning epidemiology, policy setting, economic analyses, implementation research, meta-analyses,  qualitative research to basic science in microbiology, host genetics and immune response. 

The work is done both at an academic centre and with a number of collaborating groups around the world. On these pages, we introduce the faculty members who are members of our centre and describe our training programs for students.  Find out why our Centre is a world leader in the interdisciplinary study of TB and how we work together to unravel the many mysteries of this recalcitrant disease.