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Honours Pharmacology (74 credits)

Offered by: Pharmacology and Therapeutics     Degree: Bachelor of Science

Program Requirements

Revision, June 2012. Start of revision.

The Honours program is designed as a preparation for graduate studies and research. In addition to the strong training provided by the Major program, it requires students to have direct research experience in a chosen area during their final year of study. Acceptance into the Honours program takes place in the Winter term of U2 and requires a CGPA of 3.30. Students who wish to enter the Honours program should follow the Major program; those who satisfactorily complete the first three terms with a CGPA of at least 3.30 and a mark of B or higher in core Pharmacology courses are eligible for admission. Applications can be obtained from the office of the Department of Pharmacology in the McIntyre Medical Building or on the departmental website.

U1 Required Courses (22 credits)

* Students with prior credit for CHEM 212 may take an elective in place of this course.

  • BIOL 200 Molecular Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The physical and chemical properties of the cell and its components in relation to their structure and function. Topics include: protein structure, enzymes and enzyme kinetics; nucleic acid replication, transcription and translation; the genetic code, mutation, recombination, and regulation of gene expression.

    Terms: Fall 2012

    Instructors: Thomas E Bureau, Richard D W Roy, Francesco Fagotto, Monique Zetka (Fall)

    • Fall
    • 3 hours lecture, 1 hour optional tutorial
    • Prerequisite: BIOL 112 or equivalent
    • Corequisite: CHEM 212 or equivalent
  • BIOL 202 Basic Genetics (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Introduction to basic principles, and to modern advances, problems and applications in the genetics of higher and lower organisms with examples representative of the biological sciences.

    Terms: Winter 2013, Summer 2013

    Instructors: Daniel J Schoen, Mario Chevrette, David Hipfner (Winter) David Dankort, David Hipfner (Summer)

    • Winter, Summer
    • 3 hours lecture, 1 hour optional tutorial
    • Prerequisite: BIOL 200.
    • Restriction: Not open to students who have taken or are taking CELL 204.
  • CHEM 212 Introductory Organic Chemistry 1 (4 credits) *

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : A survey of reactions of aliphatic and aromatic compounds including modern concepts of bonding, mechanisms, conformational analysis, and stereochemistry.

    Terms: Fall 2012, Winter 2013, Summer 2013

    Instructors: Youla S Tsantrizos, David Noble Harpp, Michel Daoust, Samuel Lewis Sewall, Jean-Marc Gauthier (Fall) Jean-Philip Lumb, Mitchell Huot, Michel Daoust, Jean-Marc Gauthier (Winter) Laura Pavelka, Michel Daoust, Samuel Lewis Sewall, Jean-Marc Gauthier (Summer)

    • Fall, Winter, Summer
    • Prerequisite: CHEM 110 or equivalent.
    • Corequisite: CHEM 120 or equivalent.
    • Restriction: Not open to students who are taking or have taken CHEM 211 or equivalent
    • Each lab section is limited enrolment
    • Note: Some CEGEP programs provide equivalency for this course. For more information, please see the Department of Chemistry's Web page (http://www.chemistry.mcgill.ca/advising/outside/equivalent.htm).
  • CHEM 222 Introductory Organic Chemistry 2 (4 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Modern spectroscopic techniques for structure determination. The chemistry of alcohols, ethers, carbonyl compounds, and amines, with special attention to mechanistic aspects. Special topics.

    Terms: Fall 2012, Winter 2013, Summer 2013

    Instructors: Michel Daoust, Samuel Lewis Sewall, Jean-Marc Gauthier, David Noble Harpp, Dmytro Perepichka (Fall) Karine Auclair, Michel Daoust, Mitchell Huot, Laura Pavelka (Winter) Laura Pavelka, Michel Daoust, Samuel Lewis Sewall, Jean-Marc Gauthier (Summer)

    • Fall, Winter
    • Prerequisite: CHEM 212 or equivalent.
    • Restriction: Not open to students who have taken an equivalent Organic 2 at CEGEP (see McGill University Basic Math and Sciences Equivalence Table at www.mcgill.ca/mathscitable) or who have or are taking CHEM 234.
  • PHGY 209 Mammalian Physiology 1 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of body fluids, blood, body defense mechanisms, muscle, peripheral, central, and autonomic nervous systems.

    Terms: Fall 2012

    Instructors: Ann Wechsler, Phil Gold, David S Ragsdale (Fall)

    • Fall
    • 3 hours lectures weekly
    • Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisites: BIOL 200, CHEM 212 or equivalent.
    • Restriction: Not open to students who have taken PHGY 211 or PHGY 201 or students who are taking and who have taken NSCI 200.
    • Restriction: For students in the Faculty of Science, and other students by permission of the instructor
  • PHGY 210 Mammalian Physiology 2 (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Physiology of cardiovascular, respiratory, digestive, endocrine and renal systems.

    Terms: Winter 2013

    Instructors: John H White, Ann Wechsler, Tomoko Takano (Winter)

    • Winter
    • 3 hours lectures weekly
    • Prerequisites: BIOL 112, CHEM 110, CHEM 120, PHYS 101 or PHYS 131, and PHYS 102 or PHYS 142. Pre-/co-requisite: BIOL 200, BIOL 201, BIOC 212, CHEM 212 or equivalent.
    • Restriction: Not open to students who have taken PHGY 202.
    • Restriction: For students in the Faculty of Science, and other students by permission of the instructor
    • Although PHGY 210 may be taken without the prior passing of PHGY 209, students should note that they may have some initial difficulties because of lack of familiarity with some basic concepts introduced in PHGY 209
  • PHGY 212 Introductory Physiology Laboratory 1 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Biological Signals Acquisitions, Blood, Immunology, Neurophysiology, Neuromuscular Physiology.

    Terms: Fall 2012

    Instructors: Julio Martinez Trujillo, Mladen I Glavinovic, Kresimir Krnjevic (Fall)

    • (One 3-hour lab and one 1-hour lecture every second week.)
    • Corequisite: PHGY 209.
    • Restrictions: Required for Physiology students enrolled in PHGY 209. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
    • Note: For students in a Physiology program, PHGY 212 should be taken concurrently with PHGY 209.
  • PHGY 213 Introductory Physiology Laboratory 2 (1 credit)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : Exercises illustrating fundamental principles in physiology: Central Nervous System, Cardiovascular, Respiration, Exercise Physiology, Molecular Endocrinology.

    Terms: Winter 2013

    Instructors: Michael R Guevara, Jacopo Mortola, Sheldon A Magder (Winter)

    • (One 3-hour lab and one 1-hour lecture every second week.)
    • Prerequisite: PHGY 212
    • Corequisite: PHGY 210.
    • Restrictions: Required for Physiology students enrolled in PHGY 210. Open to BA &Sc. students and to others by permission of the instructor. Not open to students who have taken PHGY 212D1/D2.
    • Note: For students in a Physiology program, PHGY 213 should be taken concurrently with PHGY 210.

U2 Required Courses (16 credits)

  • BIOC 311 Metabolic Biochemistry (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : The generation of metabolic energy in higher organisms with an emphasis on its regulation at the molecular, cellular and organ level. Chemical concepts and mechanisms of enzymatic catalysis are also emphasized. Included: selected topics in carbohydrate, lipid and nitrogen metabolism; complex lipids and biological membranes; hormonal signal transduction.

    Terms: Fall 2012

    Instructors: Julie St-Pierre, Jacques Jean Genest, Josee Dostie (Fall)

    • Fall
    • Prerequisites: BIOL 200, BIOL 201 or BIOC 212, CHEM 222
  • BIOL 301 Cell and Molecular Laboratory (4 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : An introduction to laboratory techniques with a focus on methods used to investigate fundamental questions in modern cell and molecular biology. Techniques including gene cloning, DNA and protein isolation and manipulation are covered, along with functional analysis of genes and proteins, basic bioinformatics, and computer-based experimental design and data analysis.

    Terms: Fall 2012, Winter 2013

    Instructors: Nam Sung Moon, Joseph Alan Dent, Huanquan Zheng (Fall) Nam Sung Moon, Paul Harrison, Huanquan Zheng (Winter)

    • Fall or Winter
    • 1 hour lecture and one 6-hour laboratory
    • Prerequisites: PHYS 102 or PHYS 142, BIOL 200, BIOL 201 or ANAT/BIOC 212, and BIOL 202. BIOL 206 recommended.
    • Restrictions: Not open to students who have taken or are taking BIOC 300. Requires departmental approval.
    • For approval email anne-marie [dot] sdicu [at] mcgill [dot] ca. Specify your ID number as well as the term and lab day.
  • PHAR 300 Drug Action (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Principles of pharmacology and toxicology. Frequently encountered drugs will be used as a focus to illustrate sites and mechanisms of action, distribution, metabolism, elimination and adverse side effects.

    Terms: Fall 2012

    Instructors: Edith Zorychta, Barbara F Hales (Fall)

    • Fall
    • Prerequisites: BIOL 200, PHGY 209, PHGY 210 and one of BIOL 201 or ANAT/BIOC 212 or permission of instructor.
  • PHAR 301 Drugs and Disease (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : This course further explores the basic principles of pharmacology as illustrated by drugs used in the treatment of disease. Emphasis is placed on drugs used for diseases prevalent in North America.

    Terms: Winter 2013

    Instructors: Barbara F Hales, Jane Pappas, Paul Clarke (Winter)

    • Winter
    • Prerequisite: PHAR 300 or permission of instructor.
  • PHAR 303 Principles of Toxicology (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Fundamental mechanisms by which toxic compounds damage a biological system (organelle, cell, organ, organism, ecosystem). Detection and quantification of toxicity and risk/benefit analysis are considered. Selected agents of current risk to human health or the environment are evaluated in depth.

    Terms: Winter 2013

    Instructors: Bernard Robaire, Barbara F Hales, Edith Zorychta (Winter)

    • Winter
    • Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209 and PHGY 210

U3 Required Courses (18 credits)

* PHAR 599D1 and PHAR 599D2 are taken together.

  • PHAR 503 Drug Discovery and Development 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Chemistry, mechanisms of action, and steps in drug discovery and development.

    Terms: Fall 2012

    Instructors: Dusica Maysinger (Fall)

    • Fall
    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
  • PHAR 558 Pharmacology Selected Topics (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Changing nature of selected drug targets in light of advances in studying proteins in their native cellular milieu, in the context of intact tissues, organs and whole animals, highlighting several conceptual advances in pharmacological theory with bearing on how drug targets are viewed and characterized.

    Terms: Winter 2013

    Instructors: R. Anne McKinney (Winter)

    • Prerequisite: PHAR 562 or permission of the instructor.
    • Corequisite: PHAR 563 or permission of the instructor.
  • PHAR 562 General Pharmacology 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular aspects and the nervous system; topics include molecular mechanisms of drug-action, cellular targets and rationale for therapeutics.

    Terms: Fall 2012

    Instructors: Guillermina Almazan (Fall)

    • Fall
    • Prerequisite: PHAR 301.
    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
  • PHAR 563 General Pharmacology 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Selected topics in pharmacology of the endocrine, metabolic, and cardiovascular systems. Additional topics include: pharmacogenetics/pharmacogenomics, chronopharmacology, molecular structure in pharmacology, epigenetic targets in cancer chemotherapy, and stem cell therapies.

    Terms: Winter 2013

    Instructors: Jason Tanny (Winter)

    • Winter
    • Prerequisite: PHAR 301.
    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
  • PHAR 599D1 Pharmacology Research Project (3 credits) *

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Mechanisms involved in different pathologies and drug actions.

    Terms: Fall 2012

    Instructors: R. Anne McKinney, Dusica Maysinger (Fall)

    • Fall
    • Minimum of 9 hours/week to be spent in the lab and/or library.
    • Pre-/Co-requisite: PHAR 562 and PHAR 563.
    • Restriction: U3 students with permission of instructors; students should consult instructors 3 - 4 weeks before registration.
    • Please see regulations concerning Project Courses.
    • Students must register for both PHAR 599D1 and PHAR 599D2.
    • No credit will be given for this course unless both PHAR 599D1 and PHAR 599D2 are successfully completed in consecutive terms
    • PHAR 599D1 and PHAR 599D2 together are equivalent to PHAR 599
  • PHAR 599D2 Pharmacology Research Project (3 credits) *

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : See PHAR 599D1 for course description.

    Terms: Winter 2013

    Instructors: Dusica Maysinger, R. Anne McKinney (Winter)

    • Winter
    • Minimum of 9 hours per week to be spent in the lab and/or library.
    • Prerequisite: PHAR 599D1
    • No credit will be given for this course unless both PHAR 599D1 and PHAR 599D2 are successfully completed in consecutive terms
    • PHAR 599D1 and PHAR 599D2 together are equivalent to PHAR 599

Complementary Courses (18 credits)

18 credits selected as follows:

3 credits selected from (usually in Year 1):

  • ANAT 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2013

    Instructors: Arnim Pause, Maxime Bouchard, Jason Young (Winter)

    • Winter
    • Prerequisite: BIOL 200
    • Restriction: This course is also listed as BIOC 212. Not open to students who have taken or are taking BIOC 212 or BIOL 201
  • BIOC 212 Molecular Mechanisms of Cell Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An introductory course describing the biochemistry and molecular biology of selected key functions of animal cells, including: gene expression; mitochondrial production of metabolic energy; cellular communication with the extra-cellular environment; and regulation of cell division.

    Terms: Winter 2013

    Instructors: Arnim Pause, Maxime Bouchard, Jason Young (Winter)

    • Winter
    • Prerequisite: BIOL 200
    • Restrictions: A non-terminal course intended to be followed by BIOC 311; BIOC 312 in the U2 year. Not open to students who have taken or are taking BIOL 201 or ANAT 212.
  • BIOL 201 Cell Biology and Metabolism (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : This course introduces the student to our modern understanding of cells and how they work. Major topics to be covered include: photosynthesis, energy metabolism and metabolic integration; plasma membrane including secretion, endocytosis and contact mediated interactions between cells; cytoskeleton including cell and organelle movement; the nervous system; hormone signaling; the cell cycle.

    Terms: Winter 2013

    Instructors: Gary Brouhard, Gregory G Brown (Winter)

    • Winter
    • 3 hours lecture, 1 hour optional tutorial
    • Prerequisite: BIOL 200.
    • Restriction: Not open to students who have taken or are taking ANAT 212 or BIOC 212

3 credits selected from (usually in Year 2):

  • CHEM 203 Survey of Physical Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The fundamentals of thermodynamics and chemical kinetics with applications to biomolecular systems. Thermodynamic and kinetic control of biological processes.

    Terms: Fall 2012

    Instructors: Bryan Clifford Sanctuary (Fall)

    • Fall
    • Prerequisites: CHEM 110 and CHEM 120 or equivalent.
    • Restrictions: Intended for students in biological science programs requiring only one course in physical chemistry. Not open to students who have taken or are taking CHEM 204 or CHEM 213 or CHEM 223 and CHEM 243.
  • CHEM 204 Physical Chemistry/Biological Sciences 1 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Similar to CHEM 223/CHEM 243. Emphasis on the use of biological examples to illustrate the principles of physical chemistry. The relevance of physical chemistry to biology is stressed.

    Terms: Fall 2012, Winter 2013

    Instructors: Amy Blum, William Claude Galley (Fall) Christopher Barrett (Winter)

    • Fall, Winter
    • Prerequisites: CHEM 110 and CHEM 120 or equivalent and one full course in calculus
    • Restriction: Not open to students who have taken or are taking CHEM 203 or CHEM 213 or CHEM 223 and CHEM 243.

3 credits selected from (usually in Year 2):

  • BIOL 373 Biometry (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Elementary statistical methods in biology. Introduction to the analysis of biological data with emphasis on the assumptions behind statistical tests and models. Use of statistical techniques typically available on computer packages.

    Terms: Fall 2012

    Instructors: Brian Leung (Fall)

    • Fall
    • 2 hours lecture and 2 hours laboratory
    • Prerequisite: MATH 112 or equivalent
    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.
  • MATH 203 Principles of Statistics 1 (3 credits)

    Offered by: Mathematics and Statistics (Faculty of Science)

    Overview

    Mathematics & Statistics (Sci) : Examples of statistical data and the use of graphical means to summarize the data. Basic distributions arising in the natural and behavioural sciences. The logical meaning of a test of significance and a confidence interval. Tests of significance and confidence intervals in the one and two sample setting (means, variances and proportions).

    Terms: Fall 2012, Winter 2013, Summer 2013

    Instructors: Christian Genest, Patrick Reynolds (Fall) Jose Andres Correa (Winter)

    • No calculus prerequisites
    • Restriction: This course is intended for students in all disciplines. For extensive course restrictions covering statistics courses see Section 3.6.1 of the Arts and of the Science sections of the calendar regarding course overlaps.
    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar. Students should consult http://www.mcgill.ca/student-records/transfercredits/ for information regarding transfer credits for this course.
  • PSYC 204 Introduction to Psychological Statistics (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The statistical analysis of research data; frequency distributions; graphic representation; measures of central tendency and variability; elementary sampling theory and tests of significance.

    Terms: Fall 2012, Winter 2013, Summer 2013

    Instructors: Rhonda N Amsel (Fall) David J Ostry (Winter)

    • Fall and Winter
    • Restriction: Not open to students who have passed a CEGEP statistics course(s) with a minimum grade of 75%: Mathematics 201-307 or 201-337 or equivalent or the combination of Quantitative Methods 300 with Mathematics 300
    • This course is a prerequisite for PSYC 305, PSYC 406, PSYC 310, PSYC 336
    • You may not be able to receive credit for this course and other statistic courses. Be sure to check the Course Overlap section under Faculty Degree Requirements in the Arts or Science section of the Calendar.

9 credits selected from the following upper-level science courses:

Committee approval is required to substitute an upper-level science course not in the list below.

* Note: Students may take either ANAT 458 or BIOC 458.

  • ANAT 321 Circuitry of the Human Brain (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : This course explores the functional organization of the human brain and spinal cord. The course focuses on how neuronal systems are designed to subserve specific motor, sensory, and cognitive operations.

    Terms: Fall 2012

    Instructors: James Brawer, Samuel David (Fall)

    • Fall
    • 2 hour lectures, 2 hours laboratory/tutorial
    • Prerequisites: ANAT/BIOC 212 or BIOL 201; and one of PHGY 209, NSCI 200 or PSYC 211; or permission of instructor
    • Restriction: Open to U3 students only
  • ANAT 365 Cellular Trafficking (3 credits)

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An intensive study of the processes of protein secretion and cell membrane biogenesis. Emphasis on morphological aspects of the above processes, and on the major techniques which have provided experimental evidence, namely, subcellular fractionation, cytochemistry and quantitative electron microscope radioautography.

    Terms: Fall 2012

    Instructors: Heidi McBride, Peter Scott McPherson, Timothy E Kennedy (Fall)

    • Fall
    • 2 hours lectures, 2 hours conference
    • Prerequisites: ANAT 261, ANAT 262, PHGY 209, or by permission of instructor
  • ANAT 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Anatomy and Cell Biology (Faculty of Science)

    Overview

    Anatomy & Cell Biology : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics; membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2013

    Instructors: John R Silvius, Chantal Autexier, Nathalie Lamarche (Winter)

    • Winter
    • 3 hours lectures
    • Prerequisites: BIOC 212 or ANAT 212 or BIOL 201, ANAT 262, one of PHGY 201, PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; BIOC 311 recommended
    • Restriction: This course is also listed as BIOC 458. Not open to students who are taking or who have taken BIOC 458
  • BIOC 312 Biochemistry of Macromolecules (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Gene expression from the start of transcription to the synthesis of proteins, their modifications and degradation. Topics covered: purine and pyrimidine metabolism; transcription and its regulation; mRNA processing; translation; targeting of proteins to specific cellular sites; protein glycosylation; protein phosphorylation; protein turn-over; programmed cell death (apoptosis).

    Terms: Winter 2013

    Instructors: Alain Nepveu, Bernard Turcotte, Kalle Burgess Gehring (Winter)

    • Winter
    • Prerequisites: BIOC 311, BIOL 200, BIOL 201 or BIOC 212
  • BIOC 450 Protein Structure and Function (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : Primary, secondary, tertiary and quaternary structure of enzymes. Active site mapping and site-specific mutagenesis of enzymes. Enzyme kinetics and mechanisms of catalysis. Multienzyme complexes.

    Terms: Fall 2012

    Instructors: Bhushan Nagar, Thomas Martin Schmeing, Enrico Purisima (Fall)

    • Fall
    • Prerequisites: BIOC 311, BIOC 312 and/or sufficient organic chemistry.
    • Restriction: Intended primarily for students at the U3 level
  • BIOC 454 Nucleic Acids (3 credits)

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : RNA processing, localization and stability. RNAi mechanisms, regulation and applications. Regulation of DNA replication. Genomics: human genome sequence, regulation and organization. DNA repair mechanisms. Special topics on transgenics, genetic diseases and cancer.

    Terms: Fall 2012

    Instructors: Josee Dostie, Jose Guerreiro Teodoro, Imed Eddine Gallouzi (Fall)

    • Fall
    • Prerequisites: BIOC 311, BIOC 312 or permission of instructor
  • BIOC 458 Membranes and Cellular Signaling (3 credits) *

    Offered by: Biochemistry (Faculty of Science)

    Overview

    Biochemistry : An integrated treatment of the properties of biological membranes and of intracellular signaling, including the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of regulation of cell growth, morphology, differentiation and death.

    Terms: Winter 2013

    Instructors: John R Silvius, Chantal Autexier, Nathalie Lamarche (Winter)

    • Winter
    • Prerequisites: BIOC 212, ANAT 262; one of PHGY 201, PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; and BIOC 311 or permission of instructors
    • Restriction: This course is also listed as ANAT 458. Not open to students who have taken or are taking ANAT 458 or BIOC 456
  • BIOL 300 Molecular Biology of the Gene (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A survey of current knowledge and approaches in the area of regulation of gene expression, post-transcriptional control of gene expression, and signal transduction.

    Terms: Fall 2012

    Instructors: Frieder Schöck, Paul Lasko, Siegfried Hekimi (Fall)

    • Fall
    • 3 hours lecture
    • Prerequisites: BIOL 200 and one of BIOL 201 or ANAT/BIOC 212.
  • BIOL 303 Developmental Biology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : A consideration of the fundamental processes and principles operating during embryogenesis. Experimental analyses at the molecular, cellular, and organismal levels will be presented and discussed to provide an overall appreciation of developmental phenomena.

    Terms: Winter 2013

    Instructors: Tamara Western, Yong Rao, Daniel Dufort (Winter)

    • Winter
    • 3 hours lecture and 1 hour optional tutorial
    • Prerequisites: BIOL 200, and BIOL 201 or ANAT/BIOC 212.
    • Corequisites: BIOL 202. BIOL 300 strongly recommended.
  • BIOL 306 Neural Basis of Behaviour (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : Neural mechanisms of animal behaviour; neuroethology; cellular neurophysiology, integrative networks within nervous systems; neural control of movement; processing of sensory information.

    Terms: Fall 2012

    Instructors: Gerald Pollack, Joseph Alan Dent, Alanna Watt (Fall)

    • Fall
    • 3 hours lecture
    • Prerequisites: PHYS 102 or PHYS 142 or CEGEP Physics and one of the following: BIOL 201, ANAT 212, BIOC 212 or NSCI 200
    • Restriction: Not open to students who have taken PSYC 308.
  • BIOL 314 Molecular Biology of Oncogenes (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biology (Sci) : The genes that cause cancer are altered versions of genes present in normal cells. The origins of these oncogenes, their genetic structure, regulation, and the biochemical properties of the oncogene-encoded proteins will be analyzed in an attempt to understand the origins of human and animal cancers.

    Terms: Fall 2012

    Instructors: Loydie Majewska, Nada Jabado, Giuseppina Ursini-Siegel (Fall)

    • Fall
    • 3 hours lecture
    • Prerequisites: BIOL 200; BIOL 201 or ANAT 212 /BIOC 212
  • BIOT 505 Selected Topics in Biotechnology (3 credits)

    Offered by: Biology (Faculty of Science)

    Overview

    Biotechnology : Current methods and recent advances in biological, medical, agricultural and engineering aspects of biotechnology will be described and discussed. An extensive reading list will complement the lecture material.

    Terms: Fall 2012

    Instructors: Jacalyn Vogel (Fall)

    • Fall
    • Restriction: U3 students
  • CHEM 302 Introductory Organic Chemistry 3 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Topics covered may include the following: Aromatic compounds, heterocyclic chemistry, sulfur and phosphorus chemistry, organosulfur and organophosphorus compounds, and biomolecules such as lipids, carbohydrates, amino acids, polypeptides, DNA and RNA.

    Terms: Fall 2012, Winter 2013

    Instructors: James L Gleason (Fall) Hanadi Sleiman (Winter)

    • Fall, Winter
    • Prerequisites: BIOL 112, CHEM 222, or permission of the instructor.
  • CHEM 382 Organic Chemistry: Natural Products (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Structure, synthesis, stereochemistry and biosynthesis of terpenes, alkaloids, antibiotics and selected molecules of medicinal interest.

    Terms: Winter 2013

    Instructors: Youla S Tsantrizos (Winter)

    • Winter
    • Prerequisite/corequisite: CHEM 302
  • CHEM 502 Advanced Bio-Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.

    Terms: Winter 2013

    Instructors: Karine Auclair, Laura Pavelka (Winter)

    • Winter
    • Prerequisite: CHEM 302
    • Restriction: Not open to students who have taken CHEM 402.
  • CHEM 503 Drug Design and Development 1 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Interdisciplinary course in drug design and development covering combinatorial chemistry, process chemistry, structure-activity relationship, pharmacokinetics and metabolism, mechanisms of action and steps in drug development, and principles and problems in drug design.

    Terms: Fall 2012

    Instructors: Nicolas Moitessier (Fall)

    • Fall
    • Prerequisites: CHEM 302, BIOL 200, BIOL 201 or BIOC 212, or permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.
  • CHEM 504 Drug Design and Development 2 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Computational methods used in drug design and discovery including QSAR, docking/scoring, molecular mechanics and molecular dynamics, QM/MM, library profiling and library design.

    Terms: This course is not scheduled for the 2012-2013 academic year.

    Instructors: There are no professors associated with this course for the 2012-2013 academic year.

    • Winter
    • Prerequisite: CHEM 503 and permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators
  • CHEM 522 Stereochemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Stereoisomers, their nomenclature and configuration. Conformational analysis, separation of stereoisomers, and stereocontrol in organic synthesis.

    Terms: Fall 2012

    Instructors: Nicolas Moitessier (Fall)

    • Winter
    • Prerequisite: CHEM 302
    • Restriction: Not open to students who have taken CHEM 623
  • CHEM 552 Physical Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The correlation of theory with physical measurements on organic systems; an introduction to photochemistry; solvent and substituent effects on organic reaction rates, etc.; reaction mechanisms.

    Terms: Winter 2013

    Instructors: Dmytro Perepichka (Winter)

    • Winter
    • Prerequisite: CHEM 302
  • EXMD 401 Physiology and Biochemistry Endocrine Systems (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Offered in conjunction with the Department of Physiology. The course provides a basic knowledge of endocrine systems encompassing biosynthesis, metabolism and physiological actions of hormones. Specific topics covered are hormones of the hypothalamus, pituitary, adrenals, thyroids, parathyroids, pancreas, gut and the gonads. The role of hormones and growth factors in pregnancy and fetal development are also discussed.

    Terms: Winter 2013

    Instructors: Jun-Li Liu (Winter)

    • Winter
    • Prerequisite: BIOL 200 and BIOL 201
  • EXMD 504 Biology of Cancer (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : An introduction to the biology of malignancy. A multidisciplinary approach dealing with the etiology of cancer, the biological properties of malignant cells, the host response to tumour cell growth and the principles of cancer therapy.

    Terms: Fall 2012

    Instructors: David M P Thomson (Fall)

    • Fall
    • Prerequisite (Undergraduate): A good knowledge of biology at the cellular and molecular level. Open to U3 and graduate students only
  • EXMD 511 Joint Venturing with Industry (3 credits)

    Offered by: Medicine (Faculty of Science)

    Overview

    Experimental Medicine : Using problem-based learning, the course examines the various business interactions between researchers and their business partners in support and development of research into commercial endeavours using models such as venture capital, business partnerships, or grants-in-aid.

    Terms: Winter 2013

    Instructors: K Steven Clarke, Hugh P J Bennett (Winter)

    • Winter
    • Offered in conjunction with the Centre for Continuing Education
  • MIMM 214 Introductory Immunology: Elements of Immunity (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : Basic immunology, organs and cells, elements of innate immunity, phagocytes, complement, elements of adaptive immunity, B-cells, T-cells, antigen presenting cells, MHC genes and molecules, antigen processing and presentation, cytokines and chemokines. Emphasis on anatomy and the molecular and cellular players working together as a physiological system to maintain human health.

    Terms: Winter 2013

    Instructors: Joaquin Madrenas (Winter)

    • Prerequisite: BIOL 200
    • Corequisite: BIOL 201 or ANAT 212/BIOC 212
  • MIMM 387 The Business of Science (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : The ability to select and manipulate genetic material has lead to unprecedented interest in the industrial applications of procaryotic and eucaryotic cells. Beginning in the 1970s the introduction of and subsequent refinements to recombinant DNA technology and hybridoma technology transformed the horizons of the biopharmaceutical world. This course will highlight the important events that link basic research to clinical/commercial application of new drugs and chemicals.

    Terms: Winter 2013

    Instructors: Robert A Murgita, Amit Bar-Or, Lara Khoury (Winter)

    • Winter
    • Prerequisite: At least one 200-level course in a biological or biomedical discipline or permission of instructor
  • MIMM 414 Advanced Immunology (3 credits)

    Offered by: Microbiology & Immunology (Faculty of Science)

    Overview

    Microbiology and Immun (Sci) : An advanced course serving as a logical extension of MIMM 314. The course will integrate molecular, cellular and biochemical events involved in the ontogeny of the lymphoid system and its activation in the immune response. The course will provide the student with an up-to-date understanding of a rapidly moving field.

    Terms: Fall 2012

    Instructors: Sylvie Fournier, Martin Olivier, Ciriaco Piccirillo (Fall)

    • Fall
    • 3 hour lecture
    • Prerequisite: MIMM 314
  • NEUR 310 Cellular Neurobiology (3 credits)

    Offered by: Neurology and Neurosurgery (Faculty of Science)

    Overview

    Neurology and Neurosurgery : A survey of the functional organization of nerve cells, signalling in the nervous system, and principles of neural development. Topics include cell polarity, neurotransmitters, neurotrophins, receptors and second messengers, cell lineage, guidance of axon outgrowth, and nerve regeneration. Emphasis will be placed on analysis of neurons at the molecular level.

    Terms: Winter 2013

    Instructors: Jean-Francois Cloutier, David S Ragsdale, Alyson Elise Fournier (Winter)

    • Winter
    • 2 lectures each week
    • Prerequisites or Corequisites: BIOL 201, or PHGY 209, or PHGY 210; and one of ANAT 321, ANAT 322, BIOL 306, PHGY 311.
  • PATH 300 Human Disease (3 credits)

    Offered by: Pathology (Faculty of Science)

    Overview

    Pathology : Provides a fundamental understanding of the diseases prevalent in North America, for upper level students in the biological sciences. Includes: general responses of cells and organ systems to injury; assessment of individual diseases by relating the causes, symptoms, diagnosis, treatment and prevention to the primary biological abnormalities in each disorder.

    Terms: Winter 2013

    Instructors: Edith Zorychta (Winter)

    • Winter
    • Prerequisites: BIOL 200, BIOL 201 or BIOC 212, PHGY 209. Pre-/co-requisite: PHGY 210
  • PHAR 504 Drug Discovery and Development 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.

    Terms: Winter 2013

    Instructors: Dusica Maysinger (Winter)

    • Winter
    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.
  • PHGY 311 Channels, Synapses & Hormones (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses on cellular communication in the nervous system and the endocrine system.

    Terms: Fall 2012

    Instructors: Ellis Cooper, Reza Sharif Naeini, Ali Haghighi (Fall)

    • Fall
    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 afternoons per term
    • Prerequisite: PHGY 209 or permission of the instructor.
  • PHGY 312 Respiratory, Renal, & Cardiovascular Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in renal, respiratory and cardiovascular functions explored beyond the introductory level.

    Terms: Winter 2013

    Instructors: John W Hanrahan, Jacopo Mortola, Alvin Shrier (Winter)

    • Winter
    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term
    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor
  • PHGY 313 Blood, Gastrointestinal, & Immune Systems Physiology (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In-depth presentation of experimental results and hypotheses underlying our current understanding of topics in immunology, blood and fluids, and gastrointestinal physiology.

    Terms: Winter 2013

    Instructors: Julio Martinez Trujillo, Volker Manfred Blank, Premysl Ponka (Winter)

    • Winter
    • 3 hours of lectures per week; 1-3 hours optional lab/demonstration/tutorial arranged for a maximum of 3 Wednesday afternoons per term
    • Prerequisites: PHGY 209 and PHGY 210 or equivalent, PHGY 311 or permission of the instructor
  • PHGY 314 Integrative Neuroscience (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : In depth presentation of experimental results and hypotheses underlying our current understanding of how single neurons and ensembles of neurons encode sensory information, generate movement, and control cognitive functions such as emotion, learning, and memory, during voluntary behaviours.

    Terms: Fall 2012

    Instructors: Kathleen E Cullen, Julio Martinez Trujillo, Christopher Pack (Fall)

    • Fall
    • 3 hours of lectures per week
    • Prerequisites: PHGY 209
  • PHGY 520 Ion Channels (3 credits)

    Offered by: Physiology (Faculty of Science)

    Overview

    Physiology : A discussion of the principal theories and interesting new developments in the study of ion channels. Based on a textbook, computer exercises and critical reading and presentation of research papers. Topics include: Properties of voltage-and ligand-gated channels, single channel analysis, structure and function of ion channels.

    Terms: Winter 2013

    Instructors: Reza Sharif Naeini, David S Ragsdale, Ellis Cooper (Winter)

    • Winter
    • Offered in even numbered years
    • 1 1/2 hour lecture, 1 1/2 hour seminar
    • Prerequisite: PHGY 311
    • Priority to Graduate and Honours students; others by permission of instructors.
  • PSYC 311 Human Cognition and the Brain (3 credits)

    Offered by: Psychology (Faculty of Science)

    Overview

    Psychology : The course is an introduction to the field studying how human cognitive processes, such as perception, attention, language, learning and memory, planning and organization, are related to brain processes. The material covered is primarily based on studies of the effects of different brain lesions on cognition and studies of brain activity in relation to cognitive processes with modern functional neuroimaging methods.

    Terms: Fall 2012, Summer 2013

    Instructors: Michalakis Petrides (Fall) Michalakis Petrides (Summer)

    • Fall
    • 2 lectures; 1 conference
  • PSYT 455 Neurochemistry (3 credits)

    Offered by: Psychiatry (Faculty of Science)

    Overview

    Psychiatry : Covers biochemical mechanisms underlying central nervous system function. Introduces basic neuroanatomy, CNS cell types and morphology, neuronal excitability, chemically mediated transmission, glial function. Biochemistry of specific neurotransmitters, endocrine effects on brain, brain energy metabolism and cerebral ischemia (stroke). With examples, where relevant, of biochemical processes disrupted in human CNS disease.

    Terms: Winter 2013

    Instructors: Naguib Mechawar, Ana Cecilia Flores Parkman, Tak Pan Wong (Winter)

    • Winter
    • Prerequisites: BIOC 311, BIOC 312 or permission of instructor
    • Restriction: Not open to students who have taken BIOC 455
Revision, June 2012. End of revision.
Faculty of Science—2012-2013 (last updated Dec. 20, 2012) (disclaimer)