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Note: This is the 20122013 edition of the eCalendar. For the most recent publication, click here.

Doctor of Philosophy (Ph.D.); Chemistry — Chemical Biology

Offered by: Chemistry     Degree: Doctor of Philosophy

Program Requirements

(Not offered in 2012-2013)

Thesis

A thesis for the doctoral degree must constitute original scholarship and must be a distinct contribution to knowledge. It must show familiarity with previous work in the field and must demonstrate ability to plan and carry out research, organize results, and defend the approach and conclusions in a scholarly manner. The research presented must meet current standards of the discipline; as well, the thesis must clearly demonstrate how the research advances knowledge in the field. Finally, the thesis must be written in compliance with norms for academic and scholarly expression and for publication in the public domain.

Required Courses

  • BIOC 610 Seminars in Chemical Biology 1 (1 credit)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : First multidisciplinary seminar in chemical biology.

    Terms: Fall 2012, Winter 2013

    Instructors: John R Silvius (Fall)

    • Restrictions: Open only to students registered for the M.Sc. or Ph.D. Graduate Option in Chemical Biology.
  • BIOC 611 Seminars in Chemical Biology 3 (1 credit)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : Third multidisciplinary seminar in chemical biology.

    Terms: Fall 2012, Winter 2013

    Instructors: John R Silvius (Fall)

    • Restrictions: Open only to students registered for the M.Sc. or Ph.D. Graduate Option in Chemical Biology.
  • BIOC 689 Seminars in Chemical Biology 2 (1 credit)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : Second multidisciplinary seminar in chemical biology.

    Terms: Fall 2012, Winter 2013

    Instructors: John R Silvius (Fall) John R Silvius (Winter)

    • Restrictions: Open only to students registered for the M.Sc. or Ph.D. Graduate Option in Chemical Biology. Not open to students who have taken CHEM 689.
  • BIOC 690 Seminars in Chemical Biology 4 (1 credit)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : Fourth multidisciplinary seminar in chemical biology.

    Terms: Fall 2012, Winter 2013

    Instructors: John R Silvius (Fall) John R Silvius (Winter)

    • Restrictions: Open only to students registered for the M.Sc. or Ph.D. Graduate Option in Chemical Biology. Not open to students who have taken CHEM 690.
  • CHEM 650 Seminars in Chemistry 1 (1 credit)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : A seminar course designed for graduate students in chemistry which in conjunction with McGill Chemical Society will provide exposure to a broad range of special topics within the discipline.

    Terms: Fall 2012, Winter 2013

    Instructors: Patanjali Kambhampati (Fall) Patanjali Kambhampati, Nicolas Moitessier (Winter)

    • 1 seminar
    • Required of first year graduate students in Chemistry.
  • CHEM 651 Seminars in Chemistry 2 (1 credit)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : A seminar course designed for graduate students in chemistry which in conjunction with McGill Chemical Society will provide exposure to a broad range of special topics within the discipline.

    Terms: Winter 2013

    Instructors: Patanjali Kambhampati, Nicolas Moitessier (Winter)

    • 1 seminar
    • Required of first year graduate students in Chemistry.
  • CHEM 688 Assessment (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : An evaluation that is completed before the end of the second year of registration.

    Terms: Fall 2012, Winter 2013

    Instructors: Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Fall) Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Winter)

    • Restriction: Restricted to graduate students in Chemistry.
  • CHEM 701 Comprehensive Examination 1

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : An evaluation that is completed before the end of the third year of registration.

    Terms: Fall 2012, Winter 2013

    Instructors: Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Fall) Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Winter)

    • Restriction: Ph.D. students in Chemistry.
  • CHEM 702 Comprehensive Examination 2

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : An evaluation that is completed before the end of the fourth year of registration.

    Terms: Fall 2012, Winter 2013

    Instructors: Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Fall) Karine Auclair, Ian Sydney Butler, Bruce A Arndtsen (Winter)

    • Restriction: Ph.D. students in Chemistry.

Complementary Courses

Students entering the program with an M.Sc. degree will normally take three (3) graduate-level courses. Students entering without an M.Sc. degree will normally take five (5) graduate-level courses. At least three courses must be from the following list, including at least 3 credits from the first two courses listed below.

  • BIOC 603 Genomics and Gene Expression (3 credits)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : Examination of recent developments in analysis of eukaryotic cell genomes and control of gene expression. Molecular genetics; genomics and the bioinformatics of analysis of genomic and functional-genomic data; mechanisms and signal-transduction pathways for regulation of gene expression; applications to human disease.

    Terms: Fall 2012

    Instructors: William Joseph Muller, Jose Guerreiro Teodoro, Imed Eddine Gallouzi (Fall)

    • Fall
    • Prerequisites: BIOC 454 and permission of instructor.
  • BIOC 604 Macromolecular Structure (3 credits)

    Offered by: Biochemistry (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Biochemistry : X-Ray crystallography, NMR spectroscopy, computational methods and theoretical approaches to the determination and analysis of macromolecular structures. Theory and practical applications will be covered. Examples will include interpretation of structure as it applies to biological functions. In conjunction with the Université de Montréal.

    Terms: Winter 2013

    Instructors: Bhushan Nagar (Winter)

    • Winter
    • Prerequisite: BIOC 450 or equivalent
    • Lectures in French and English
    • Offered in the Fall term, in even alternate years.
  • CHEM 502 Advanced Bio-Organic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : This course will cover biologically relevant molecules, particularly nucleic acids, proteins, and their building blocks. In each case, synthesis and biological functions will be discussed. The topics include synthesis of oligonucleotides and peptides; chemistry of phosphates; enzyme structure and function; coenzymes, and enzyme catalysis; polyketides; antiviral and anticancer agents.

    Terms: Winter 2013

    Instructors: Karine Auclair, Laura Pavelka (Winter)

    • Winter
    • Prerequisite: CHEM 302
    • Restriction: Not open to students who have taken CHEM 402.
  • CHEM 503 Drug Design and Development 1 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Interdisciplinary course in drug design and development covering combinatorial chemistry, process chemistry, structure-activity relationship, pharmacokinetics and metabolism, mechanisms of action and steps in drug development, and principles and problems in drug design.

    Terms: Fall 2012

    Instructors: Nicolas Moitessier (Fall)

    • Fall
    • Prerequisites: CHEM 302, BIOL 200, BIOL 201 or BIOC 212, or permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.
  • CHEM 504 Drug Design and Development 2 (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Computational methods used in drug design and discovery including QSAR, docking/scoring, molecular mechanics and molecular dynamics, QM/MM, library profiling and library design.

    Terms: This course is not scheduled for the 2012-2013 academic year.

    Instructors: There are no professors associated with this course for the 2012-2013 academic year.

    • Winter
    • Prerequisite: CHEM 503 and permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators
  • CHEM 514 Biophysical Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Physical chemistry concepts needed to understand the function of biological systems at the molecular level, including the structure, stability, transport, and interactions of biological macromolecules.

    Terms: Winter 2013

    Instructors: Paul Wiseman, Anthony Mittermaier, Amy Blum (Winter)

    • Winter
    • Prerequisite: CHEM 203 or CHEM 204 or CHEM 223 and CHEM 243, or permission of instructor.
    • Restriction: Not open to students who have taken CHEM 404.
  • CHEM 522 Stereochemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : Stereoisomers, their nomenclature and configuration. Conformational analysis, separation of stereoisomers, and stereocontrol in organic synthesis.

    Terms: Fall 2012

    Instructors: Nicolas Moitessier (Fall)

    • Winter
    • Prerequisite: CHEM 302
    • Restriction: Not open to students who have taken CHEM 623
  • CHEM 591 Bioinorganic Chemistry (3 credits)

    Offered by: Chemistry (Faculty of Science)

    Overview

    Chemistry : The roles of transition and main group elements in biology and medicine will be examined with an emphasis on using tools for structure and genome searching as well as becoming acquainted with experimental spectroscopic methods useful for bioinorganic chemistry such as macromolecular X-ray diffraction, EPR and EXAFS.

    Terms: Winter 2013

    Instructors: David Bohle (Winter)

    • Winter
    • Prerequisite: CHEM 381
    • Restriction: For Honours and Major Chemistry students or with permission
  • CHEM 621 Reaction Mechanisms in Organic Chemistry (5 credits)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : A systematic survey of the mechanisms of the most common organic reactions from studies of reactions in the current literature.

    Terms: Fall 2012

    Instructors: Chaojun Li (Fall)

  • CHEM 629 Organic Synthesis (5 credits)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : An advanced course in the synthesis of organic molecules with an emphasis on stereoselective transformations. Topics will include multiple bond formation, functional group interconversions, carbon-carbon bond formation and stereoselective oxidations and reductions.

    Terms: Winter 2013

    Instructors: Jean-Philip Lumb (Winter)

  • CHEM 655 Advanced NMR Spectroscopy (4 credits)

    Offered by: Chemistry (Faculty of Science)

    Administered by: Graduate Studies

    Overview

    Chemistry : Advanced techniques of nuclear magnetic resonance spectroscopy, Fourier transform methods, multiple pulsing, two-dimensional pulse sequencing.

    Terms: Winter 2013

    Instructors: Anthony Mittermaier (Winter)

    • 1 lecture
    • Prerequisite: CHEM 555 or equivalent.
  • PHAR 503 Drug Discovery and Development 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Chemistry, mechanisms of action, and steps in drug discovery and development.

    Terms: Fall 2012

    Instructors: Dusica Maysinger (Fall)

    • Fall
    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
  • PHAR 504 Drug Discovery and Development 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Nobel Prize-winning discoveries as a basis for drug development.

    Terms: Winter 2013

    Instructors: Dusica Maysinger (Winter)

    • Winter
    • Prerequisites: PHAR 301 or PHAR 303; or permission of instructor
    • Restriction: U3 and graduate students. Students can register only with permission of coordinators.
  • PHAR 562 General Pharmacology 1 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology with an emphasis on molecular aspects and the nervous system; topics include molecular mechanisms of drug-action, cellular targets and rationale for therapeutics.

    Terms: Fall 2012

    Instructors: Guillermina Almazan (Fall)

    • Fall
    • Prerequisite: PHAR 301.
    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
  • PHAR 563 General Pharmacology 2 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Science)

    Overview

    Pharmacology and Therapeutics : Selected topics in pharmacology of the endocrine, metabolic, and cardiovascular systems. Additional topics include: pharmacogenetics/pharmacogenomics, chronopharmacology, molecular structure in pharmacology, epigenetic targets in cancer chemotherapy, and stem cell therapies.

    Terms: Winter 2013

    Instructors: Jason Tanny (Winter)

    • Winter
    • Prerequisite: PHAR 301.
    • Restriction: Open to U3 students in the minor, major or honours program in Pharmacology, or with permission of instructor.
  • PHAR 707 Topics in Pharmacology 6 (3 credits)

    Offered by: Pharmacology and Therapeutics (Faculty of Medicine)

    Administered by: Graduate Studies

    Overview

    Pharmacology and Therapeutics : Topics in pharmacology.

    Terms: Fall 2012

    Instructors: Martine Culty (Fall)

    • Prerequisite: Permission of the Instructor.

The remaining credits may be 500-, 600-, or 700-level courses approved by the Department.

Faculty of Science—2012-2013 (last updated Dec. 20, 2012) (disclaimer)