The Department of Pharmacology and Therapeutics offers training leading to M.Sc. (Thesis) and Ph.D. degrees.
The Department also offers the Chemical Biology Interdisciplinary Graduate Option, together with the Departments of Biochemistry and Chemistry. Students interested in training in this option must first be accepted for graduate studies by one of the participating departments. Information on this option can be found at: www.mcgill.ca/biochemistry/chemicalbiology.
Pharmacology is a multidisciplinary science that deals with all aspects of drugs and their interactions with living organisms. Thus, pharmacologists study the physical and chemical properties of drugs, their biochemical and physiological effects, mechanisms of action, pharmacokinetics, and therapeutic and other uses. The Department offers broad exposure and training in both basic and clinical research in a range of areas of specialty, including neuropharmacology, reproductive, endocrine, receptor, cardiovascular, cancer, developmental, autonomic, clinical, and biochemical pharmacology, molecular biology, and toxicology.
The present 52 full and affiliate members of the Department have research laboratories located in the McIntyre Medical Sciences Building and in a variety of hospitals, institutes, and industry including the Douglas Hospital Research Centre, Allan Memorial Institute, Montreal Children's Hospital, Montreal General Hospital, Royal Victoria Hospital, Montreal Heart Institute, Lady Davis Research Institute, Pfizer Canada, and Merck Frosst Canada Inc. The participation of researchers from both industry and government ensures the relevance of the Department's applications-oriented training programs.
| Master of Science (M.Sc.); Pharmacology (Thesis) — Chemical Biology (47 credits) |
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The Chemical Biology Thematic Group is engaged in a diverse range of research topics that span structural biology, enzymology, nucleic acid research, signalling pathways, single molecule biophysics, and biophysical chemistry of living tissues. Among the themes that unite the research being performed in this group is trying to learn new chemistry and physics from biological systems.
We have projects relating to pharmaceutically relevant enzymes such as those involved in drug metabolism and antibiotic resistance; development of therapeutic agents in the control of inflammation, cancer, and viral infections; the chemical biology of NO; quantification of bioenergetic markers of metabolism; self-assembly mechanisms of the HIV-1 virion capsid; liposome microarray systems to address membrane protein dynamics and recognition; studies on reactive oxygen species translocation across the aqueous/lipid membrane interface; RNAi/antisense technologies; dynamic combinatorial chemistry; protein dynamics and function; mechanistic aspects involved in cellular adhesion and transport in membrane and zeolite channels; and cutting-edge microscopes used to examine transport, motility, and reactivity in cells.
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| Doctor of Philosophy (Ph.D.); Pharmacology — Chemical Biology |
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The Chemical Biology Thematic Group is engaged in a diverse range of research topics that span structural biology, enzymology, nucleic acid research, signalling pathways, single molecule biophysics, and biophysical chemistry of living tissues. Among the themes which unite the research being performed in this group is the attempt to learn new chemistry and physics from biological systems.
We have projects relating to pharmaceutically relevant enzymes such as those involved in drug metabolism and antibiotic resistance; development of therapeutic agents in the control of inflammation, cancer and viral infections; the chemical biology of NO; quantification of bioenergetic markers of metabolism; self-assembly mechanisms of the HIV-1 virion capsid; liposome microarray systems to address membrane protein dynamics and recognition; studies on reactive oxygen species translocation across the aqueous/lipid membrane interface; RNAi/antisense technologies; dynamic combinatorial chemistry; protein dynamics and function; mechanistic aspects involved in cellular adhesion and transport in membrane and zeolite channels; and cutting-edge microscopes used to examine transport, motility, and reactivity in cells.
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