CGRp and the tuning of linearly in vestibular processing - PHGY 396 Undergraduate Research Project Application Form

Supervisor's Name: Kathleen Cullen

Supervisor's Email: kathleen.cullen [at] mcgill.ca

Supervisor's Phone: 514 398-5709

Supervisor's Website:

Supervisor's department: Physiology

Course number: PHGY 396 (Physiology)

Term: Winter 2013-2014

Project start date: Monday, January 6, 2014

Project end date: Friday, April 11, 2014

Project title: CGRp and the tuning of linearly in vestibular processing

Project description (50-100 words suggested): The functional role of the brain’s efferent projection to the vestibular component of the inner ear remains a mystery. Calcitonin-gene related peptide (CGRP) is a neuroactive peptide known to act at efferent synapses and their targets in hair cell organs including the cochlea and lateral line.  In this project, we will address  whether and how the loss of CGRP influences the linearity of vestibular system function by comparing the vestibular ocular reflex in CGRP null (-/-) and WT mice .

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade): Based on the supervisor’s assessment of a combination of overall performance (35%) and on the quality of the oral (15%) and written (50%) reports.

Project status: This project is taken. The professor has no more '396' projects this term.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Animal subjects.