Supervisor's Name: Nicolas Moitessier
Supervisor's Email: nicolas.moitessier [at] mcgill.ca
Supervisor's Phone: 514 398 8543
Supervisor's Website: moitessier-group.mcgill.ca
Supervisor's department: Chemistry
Course number: CHEM 396 (Chemistry)
Term: Fall 2013-2014
Project start date: Tuesday, September 3, 2013
Project end date: Tuesday, December 3, 2013
Project title: Novel computational methods for the design of biocatalysts
Project description (50-100 words suggested): Biocatalysts (enzymes) are greener, easier and often more selective than metal catalysts and organocatalysts. However their development is difficult and lengthy. Traditionally, thousands of enzyme mutants have to be generated and tested before identifying an efficient biocatalyst if any. We propose to develop a computational method to design efficient biocatalysts by identifying the optimal mutations of a known enzyme.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): Lab performance 40%; Final report 50%; Oral presentation 10%
Project status: This project is taken; however students may contact the professor to discuss other possible '396' projects this term.
How students can apply: Bring a printed copy of this application form and your advising transcript to me during office hours.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves NEITHER animal subjects, nor human subjects, nor biohazardous substances, nor radioactive materials, nor handling chemicals, nor using lasers.