'Distribution of Elastic Fibers in the Heart: Influence of Fibulin-4 Levels' - ANAT 396 Undergraduate Research Project Application Form

Supervisor's Name: Elaine C. Davis, Ph.D.

Supervisor's Email: elaine.davis [at] mcgill.ca

Supervisor's Phone: 514-398-5893

Supervisor's Website:

Supervisor's department: Anatomy and Cell Biology

Course number: ANAT 396 (Anatomy and Cell Biology)

Term: Fall 2013-2014

Project start date: Tuesday, September 3, 2013

Project end date: Tuesday, December 3, 2013

Project title: Distribution of Elastic Fibers in the Heart: Influence of Fibulin-4 Levels

Project description: The project will involve the localization of elastin and elastic fiber-related proteins in the hearts of mice expressing various levels of fibulin-4.  Preliminary data suggests abnormal elastic fiber assembly/distribution in the heart when the expression of fibulin-4 is altered. Hearts will be collected at different developmental ages from wildtype and fibulin-4 mutant mice. Elastin, fibrillin and other proteins that are critical for elastic fiber assembly will be investigated.

Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.

Grading scheme (The final report must be worth at least 50% of final grade):Final Report 50%; Presentation to Lab Group 25%; Research Skill/Effort 25%.

Project status: This project is taken. The professor has no more '396' projects this term.

How students can apply: N/A; this project is filled.

Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves NEITHER animal subjects, nor human subjects, nor biohazardous substances, nor radioactive materials, nor handling chemicals, nor using lasers.