'Proteomic Analysis of Trichuris suis excreted/secreted products' - MIMM 396 Undergraduate Research Project Application Form
INSTRUCTIONS - PROFESSORS: Please print and review this form. Complete or correct the sections, as applicable, from "Supervisor's Name" to "Ethics, safety, and training". Please sign and date near the bottom ("Supervisor's signature").
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted here. Either way, print and review this form. Complete or correct the sections, from "Student's Name" to "Student's Level", and sign ("Student signature"). Ask your supervisor to sign her/his section near the bottom. Take it to the department* corresponding to the course number in Section A; this may or may not be your own department. (* EXCEPTIONS: For NSCI 396 and COGS 396, please bring it to the Interdisciplinary Programs Adviser in Dawson Hall.) Do not register for a '396' course on Minerva until you receive departmental permission. Have a discussion with your supervisor about time/work expectations, keeping in mind that this is a 3-credit course (roughly, 10 hours per week for 12 weeks). Remember that a '396' course is an elective.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, please notify student. If approved, please give student permission to register on Minerva, and send a copy of this form (with signatures) to the Office for Undergraduate Research in Science (either fax, or internal mail to Dawson Hall 408-A, or PDF scan + email).
QUESTIONS OR FEEDBACK? Contact the Office for Undergraduate Research in Science.
Supervisor's Name: Armando Jardim
Supervisor's Email: armando [dot] jardim [at] mcgill [dot] ca
Supervisor's Phone: 514-398-7727
Supervisor's department: Microbiology and Immunology; Parasitology
Course number: MIMM 396 (Microbiology)
Term: Fall 2013-2014
Project start date: Tuesday, September 3, 2013
Project end date: Tuesday, December 3, 2013
Project title: Proteomic Analysis of Trichuris suis excreted/secreted products
Project description (50-100 words suggested): Differential analysis and annotation of excreted/secreted proteins released by larval and adult stages of T. suis. This bioinformatic analysis, will create a short list of molecules that dampen the TLR-9 mediated production of IL-12 by Dendritic cells. In addition, chromatographic separation of ESP will be performed to identify bioactive/immunologically active parasite proteins.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): 25% - Comparative analysis of T. suis secretome with other helminths. 25%- Analysis of categories and potential biological/immunological role of secreted proteins. 50% - 20 page report on the work done, plus a 20 minute presentation, evaluated by Dr. Geary, Dr. Jardim and Dr. Leroux.
Project status: This project is taken.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves Biohazardous substances.