'Cancer and stem cell interaction in repair of radiation-induced lung damage' - ANAT 396 Undergraduate Research Project Application Form
INSTRUCTIONS - PROFESSORS: Please print and review this form. Complete or correct the sections, as applicable, from "Supervisor's Name" to "Ethics, safety, and training". Please sign and date near the bottom ("Supervisor's signature").
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted here. Either way, print and review this form. Complete or correct the sections, from "Student's Name" to "Student's Level", and sign ("Student signature"). Ask your supervisor to sign her/his section near the bottom. Take it to the department* corresponding to the course number in Section A; this may or may not be your own department. (* EXCEPTIONS: For NSCI 396 and COGS 396, please bring it to the Interdisciplinary Programs Adviser in Dawson Hall.) Do not register for a '396' course on Minerva until you receive departmental permission. Have a discussion with your supervisor about time/work expectations, keeping in mind that this is a 3-credit course (roughly, 10 hours per week for 12 weeks). Remember that a '396' course is an elective.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, please notify student. If approved, please give student permission to register on Minerva, and send a copy of this form (with signatures) to the Office for Undergraduate Research in Science (either fax, or internal mail to Dawson Hall 408-A, or PDF scan + email).
QUESTIONS OR FEEDBACK? Contact the Office for Undergraduate Research in Science.
Supervisor's Name: Issam El Naqa
Supervisor's Email: issam [dot] elnaqa [at] mcgill [dot] ca
Supervisor's Phone: 5149341934 ext. 45302
Supervisor's department: Oncology
Course number: ANAT 396 (Anatomy and Cell Biology)
Term: Fall 2013-2014
Project start date: Tuesday, September 3, 2013
Project end date: Tuesday, December 3, 2013
Project title: Cancer and stem cell interaction in repair of radiation-induced lung damage
Project description (50-100 words suggested): We are investigating several methods to mitigate and repair lung radiation-induced damage in lung cancer patients who receive radiotherapy as part of their treatment. One approach is to utilize tissue regeneration approaches. This project focuses on how different environmental and biological factors can affect the differentiation of mesenchymal stem cells (MSCs) into progenitor lung cells that are able to mitigate lung damage before fibrosis can occur. This is done via co-culture and tri-culture in different mediums followed by testing for specific markers using PCR and immunohistochemical staining. The main aim is to determine whether or not the route of differentiation changes in a cancerous environment and the factors that may influence that.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): 40% Lab Performance; 10% Oral Lab Presentation; 50% Final Report.
Project status: This project is taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves:; Animal subjects; Biohazardous substances; Handling chemicals.