'Bacterial effector protein interactions in Y2H' - MIMM 396 Undergraduate Research Project Application Form
INSTRUCTIONS - PROFESSORS: Please print and review this form. Complete or correct the sections, as applicable, from "Supervisor's Name" to "Ethics, safety, and training". Please sign and date near the bottom ("Supervisor's signature").
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted here. Either way, print and review this form. Complete or correct the sections, from "Student's Name" to "Student's Level", and sign ("Student signature"). Ask your supervisor to sign her/his section near the bottom. Take it to the department* corresponding to the course number in Section A; this may or may not be your own department. (* EXCEPTIONS: For NSCI 396 and COGS 396, please bring it to the Interdisciplinary Programs Adviser in Dawson Hall.) Do not register for a '396' course on Minerva until you receive departmental permission. Have a discussion with your supervisor about time/work expectations, keeping in mind that this is a 3-credit course (roughly, 10 hours per week for 12 weeks). Remember that a '396' course is an elective.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, please notify student. If approved, please give student permission to register on Minerva, and send a copy of this form (with signatures) to the Office for Undergraduate Research in Science (either fax, or internal mail to Dawson Hall 408-A, or PDF scan + email).
QUESTIONS OR FEEDBACK? Contact the Office for Undergraduate Research in Science.
Supervisor's Name: Samantha Gruenheid
Supervisor's Email: samantha [dot] gruenheid [at] mcgill [dot] ca
Supervisor's Phone: 514-398-2138
Supervisor's department: Microbiology and Immunology
Course number: MIMM396 (Microbiology)
Term: Winter 2012-2013
Project start date: Monday, January 7, 2013
Project end date:
Project title: Bacterial effector protein interactions in Y2H
Project description: Previously our lab has characterized an interaction between the bacterial effector protein N1eA and the human protein Sec24. We have characterized the critical portions of N1eA involved in the interaction but not the critical portions of Sec24. The current project will analyze domains of Sec24 and specific mutants to better define the domains of Sec24 involved in N1eA binding. Additionally, we have identified a second bacterial effector protein with homology to Sec24. Time permitting; the possible interaction between N1eA and this protein will be investigated.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme: 50% lab performance 50% report (~10 pages).
Project status: This project is taken. The professor has no more '396' projects this term.
How students can apply: This project is taken. (After all parts of this application form are completed, and the hard copy is signed by the professor and the student, bring this application form and your unofficial transcript to Prof. Gregory Marczynski during office hours, who will review/approve as the course coordinator for MIMM 396 (Microbiology) or MIMM 397 (Immunology).)
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves biohazardous substances and handling chemicals.