INSTRUCTIONS - PROFESSORS: Please print and review this form. Complete or correct the sections, as applicable, from "Supervisor's Name" to "Ethics, safety, and training". Please sign and date near the bottom ("Supervisor's signature").
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it from www.mcgill.ca/science/research/ours/396 after it has been posted. Either way, print and review this form. Complete or correct the sections, from "Student's Name" to "Student's Level", and sign ("Student signature). Ask your supervisor to sign her/his section near the bottom. Take it to the department corresponding to the course number; this may or may not be your own department. Do not register for a '396' course on Minerva until you receive departmental permission. Have a discussion with your supervisor about time/work expectations, keeping in mind that this is a 3-credit course (roughly, 10 hours per week for 12 weeks). Remember that a '396' course is an elective.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, please notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science (either fax 514-398-8102, or internal mail to Dawson Hall 408-A, or PDF scan + email).
QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964
Supervisor's Name: Mark Wainberg
Supervisor's Email: mark [dot] wainberg [at] mail [dot] mcgill [dot] ca
Supervisor's Phone: (514) 340-8260 x.5282
Supervisor's Website: http://www.mcgill.ca/microimm/department/professors/wainberg
Supervisor's department: Microbiology and Immunology
Course number: MIMM396 (Microbiology)
Term: Winter 2011-2012
Project start date: Monday, January 9, 2012
Project end date: Monday, April 16, 2012
Project title: Redistribution of extracelluar HIV-1 as a consequence of treatment with entry inhibitors
Project description: Our lab has recently shown that redistribution of HIV-1 with entry inhibitors acting at 2 of 3 stages of the entry cascade. We plan to assess whether entry inhibitors acting at the first stage of the entry cascade exhibit the redistribution effect, and if so, to what degree. The student will be responsible for generating virus stocks, culturing cells in our P3 facility, and determining the amount of virus both extracellularly and intracellularly using qPCR methodology. All of these techniques are available in the lab, yet require modifications that call for ingenuity and originality. The resuts of these experiments will help illuminate the effects of HIV entry inhibitors, which as a drug class warrant further investigation.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): Final grade shall be based on laboratory performance as evaluated by the research supervisor (50%) and the final written research report (minimum 10 pages) graded by the supervisor and the course coordinator or the coordinator's delegate (50%).
Project status: This project is taken. The professor has no more '396' projects this term.
How students can apply: N/A; this project is filled.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves: Biohazardous substances; Handling chemicals.
Student's McGill ID:
Student's Email (first [dot] last [at] mail [dot] mcgill [dot] ca):
Student's Level (U0 / U1 / U2 / U3):
Student's signature - I have not applied for another '396' course in this term:
Supervisor's signature - I give my permission for the student identified above to register for this project under my supervision:
Unit chair/director/designate's name:
Unit chair/director/designate's signature - I certify that this project conforms to departmental requirements for 396 courses: