'Cryo-EM study of p97 with an adaptor protein' - ANAT 396 Undergraduate Research Project Application Form
INSTRUCTIONS - PROFESSORS: Please print and review this form. Complete or correct the sections, as applicable, from "Supervisor's Name" to "Ethics, safety, and training". Please sign and date near the bottom ("Supervisor's signature").
INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it from www.mcgill.ca/science/research/ours/396 after it has been posted. Either way, print and review this form. Complete or correct the sections, from "Student's Name" to "Student's Level", and sign ("Student signature). Ask your supervisor to sign her/his section near the bottom. Take it to the department corresponding to the course number; this may or may not be your own department. Do not register for a '396' course on Minerva until you receive departmental permission. Have a discussion with your supervisor about time/work expectations, keeping in mind that this is a 3-credit course (roughly, 10 hours per week for 12 weeks). Remember that a '396' course is an elective.
INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and send a copy of this form (with signatures) to the Office for Undergraduate Research in Science (either fax 514-398-8102, or internal mail to Dawson Hall 408-A, or PDF scan + email).
QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964
Supervisor's Name: Isabelle Rouiller
Supervisor's Email: isabelle [dot] rouiller [at] mcgill [dot] ca
Supervisor's Phone: (514) 398-3244
Supervisor's Website: http://www.mcgill.ca/rouiller-lab
Supervisor's department: Anatomy and Cell Biology
Course number: ANAT396 (Anatomy and Cell Biology)
Term: Winter 2011-2012
Project start date: Monday, January 9, 2012
Project end date: Monday, April 16, 2012
Project title: Cryo-EM study of p97 with an adaptor protein
Project description: To perform its function in the ERAD pathway, p97 interacts with various adaptor proteins. The force provided by ATP hydrolysis in p97 is transfered to the adaptor protein. The conformational changes induced to the adaptor are currently unknown. The complex p97-adpator will be studied using cryo-electron microscopy as to determine the conformations of the complex in presence of different nucleotides.
Prerequisite: 1 term completed at McGill + CGPA of 3.0 or higher; or permission of instructor.
Grading scheme (The final report must be worth at least 50% of final grade): TO BE CONFIRMED - laboratory performance, 50%; final written research report, 50%.
Other project information: We have several adaptor proteins. A comparative study between different adaptor proteins is planned.
Project status: This project is taken; however students may contact the professor to discuss other possible '396' projects this term.
How students can apply: Bring a printed copy of this application form and your advising transcript to me during office hours.
Ethics, safety, and training: Supervisors are responsible for the ethics and safety compliance of undergraduate students. This project involves handling chemicals.
Student's McGill ID:
Student's Email (first [dot] last [at] mail [dot] mcgill [dot] ca):
Student's Level (U0 / U1 / U2 / U3):
Student's signature - I have not applied for another '396' course in this term:
Supervisor's signature - I give my permission for the student identified above to register for this project under my supervision:
Unit chair/director/designate's name:
Unit chair/director/designate's signature - I certify that this project conforms to departmental requirements for 396 courses: