| INSTRUCTIONS - PROFESSORS: Fill out Sections A & B then submit this form online. (You will receive an email copy of the form. The Office for Undergraduate Research in Science will also post the project online, indicating whether the project is open for students to apply or taken.) DONE | |
| INSTRUCTIONS - STUDENTS: You may receive this form by email, or you may download it after it has been posted. Either way, print this form. Complete and sign Section C on the hardcopy. Ask your supervisor to sign Section D. Take it to the department corresponding to the course number in Section A (this may or may not be your own department). Do not register for a '396' course on Minerva until you receive departmental permission. | |
| INSTRUCTIONS - DEPARTMENTS: After the unit chair/director/designate approves (or not) this project, notify student. If approved, please give student permission to register on Minerva, and fax this form (with signatures) to the Office for Undergraduate Research in Science at 514-398-8102. | |
| QUESTIONS OR FEEDBACK? Contact Victor Chisholm by email, or phone 514-398-5964. | |
| SECTION A: SUPERVISOR INFORMATION | |
| Name: | Ursula Stochaj |
| Email: | ursula [dot] stochaj [at] mcgill [dot] ca |
| Phone: | 514-398-2949 |
| Website: | |
| Supervisor's department: | Physiology |
| Supervisor's department (if none of the above) | |
| Course number: | PHGY396 (Physiology) |
| SECTION B: PROJECT INFORMATION | |
| Term: | Winter 2009-2010 |
| Project start date: | January 2010 |
| Project end date: | April 2010 |
| Project title: | Nuclear transport of chaperones |
| Project description: | Human health in Canada is primarily affected by heart disease or stroke, conditions which expose cells of the heart or brain to stress. This stress exposure causes damage and may ultimately lead to cell death. Prevention of and recovery from stress-induced injuries require several factors to repair damaged cells. Heat shock proteins, in particular hsc70s, are essential for these repair processes. In response to stress, hsc70s accumulate transiently in nucleoli to restore the assembly of ribosomal subunits and other crucial processes. This project will study the molecular mechanisms that underlie the nucleolar targeting of an essential chaperone. |
| Prerequisite: | 1 term completed at McGill and CGPA of 3.0 or higher. |
| Other prerequisite, if applicable: | |
| Grading scheme (The final report must be worth at least 50% of final grade): | The final report will be worth 50% of the final grade. Laboratory work will be worth 50% of the final grade. |
| Other project information: | |
| Project status - This project is: | Taken. |
| How students can apply: | N/A; this project is filled. |
| If other, please specify: | |
| Ethics, safety, and training | |
| Which of the following, if any, is involved? | |
| Animal subjects | [ ] |
| Human subjects | [ ] |
| Biohazardous substances | [X] |
| Radioactive materials | [ ] |
| Handling chemicals | [X] |
| Using lasers | [ ] |
| Supervisors are responsible for the ethics and safety compliance of undergraduate students. | |
| SECTION C: STUDENT INFORMATION | |
| Do not complete this section unless/until the student is identified. | |
| Name: | |
| McGill ID: | |
| Email (first [dot] last [at] mail [dot] mcgill [dot] ca): | |
| Phone: | |
| Program (E.g., B.Sc. Maj. Chem. Min. Biol.): | |
| Level (U0 / U1 / U2 / U3): | |
| Student signature - I have not applied for another '396' course in this term: | |
| SECTION D: APPROVALS. | |
| Do not complete this section unless/until the student is identified. | |
| Supervisor: I give my permission for the student identified in section C to register for this project under my supervision. | |
| Supervisor's signature: | |
| Date: | |
| Unit chair/director/designate: I certify that this project conforms to departmental requirements for 396 courses. | |
| Unit chair/director/designate's name: | |
| Unit chair/director/designate's signature: | |
| Date: | |