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Standard Operating Procedures (SOPs)

Most used SOPs | All SOPs listed by numberOther SOPs | Draft SOPs for Review by all

Standard Operating Procedures (SOPs) provide a detailed description of commonly used procedures. SOPs offer investigators an alternative to writing detailed procedures in their protocol. Any deviation from the approved procedures must be clearly described and justified in the Animal Use Protocol application in Darwin. Approval of the protocol indicates approval of the deviation from the SOP for that project only. The following Standard Operating Procedures (SOPs) were created and/or revised by the Veterinary Care Subcommittee and approved by the University Animal Care Committee.


List of the most commonly used SOPs and blank forms:

Personnel Section: Certification for Non-rodent Non-rabbit Training (to use if no workshop available for the species, to be completed by appropriate instructor)

Transport: 501 01 - Animal Transport and Use Outside of Facilities 

Mice SOPs
531 01 - Animal Acquisition, Receiving, and Acclimation
403 01 - Guidelines for Blood Collection Volumes and Frequency
101 02 - Rodent Analgesia
110 03 - Mouse Anesthesia
201 02 - Rodent Surgery
202 01 - Rodent Stereotaxic Surgery
402 01 - Tissue Collection for Genotyping Mice
405 01 - Monoclonal Antibody Production In Mice

Rat SOPs
531 01 - Animal Acquisition, Receiving, and Acclimation
403 01 - Guidelines for Blood Collection Volumes and Frequency
101 02 - Rodent Analgesia
111 02 - Rat Anesthesia
201 02 - Rodent Surgery
202 01 - Rodent Stereotaxic Surgery
407 01 - Polyclonal Antibody Production In Rats

Farm SOPs: MAC FACC Web site

Clinical endpoint section:
410 01 - Humane Endpoints
415 02 - Humane Endpoints for Rodent Cancer Models
Body Condition Score Outline Mice
Body Condition Score Outline For Rats
412 01 - Humane Endpoints for Aging Rodents

Euthanasia: 301 01 - Rodent Euthanasia


SOPs listed by category/number:

First three digits is the number of the SOP.
Last two digits is the version number (SOPs will be updated on a regular basis), example - 201.02 is SOP#201, 2nd version.

Analgesia 

101 02 - Rodent Analgesia
102 01 - Rabbit Analgesia
103 01 - Non-Human Primate Analgesia
104 01 - Dog Analgesia
105 01 - Cat Analgesia
106 01 - Swine Analgesia
107 01 - Bird Analgesia
108 01 - Fish, Amphibian and Reptile Analgesia
109 01 - Ruminant Analgesia


 Anesthesia

110 03 - Mouse Anesthesia
111 02 - Rat Anesthesia
112 02 - Hamster Anesthesia
113 02 - Guinea Pig 113_02-Guinea_Pig_Anesthesia.doc
114 01 - Rabbit Anesthesia
115 01 - Non-Human Primate Anesthesia
116 01 - Dog Anesthesia
117 01 - Cat Anesthesia
118 01 - Fish and Aquatic Amphibian Anesthesia
119 01 - Swine Anesthesia
120 01 - Anesthesia Protocol Lung Physiology Measurements 


Surgery

201 02 - Rodent Surgery
202 01 - Rodent Stereotaxic Surgery
203 01 - Large Animal Surgery 


Euthanasia

301 01 - Rodent Euthanasia
302 01 - Large Animal Euthanasia
303 01 - Fish and Amphibian Euthanasia
304 01 - Avian Euthanasia 


Experimental Guidelines

 401 02 - Controlled Drugs
402 01 - Tissue Collection for Genotyping Mice
403 01 - Guidelines for Blood Collection Volumes and Frequency
Blood Volumes Annex

 404 01 - Substance Administration
405 01 - Monoclonal Antibody Production In Mice
406 01 - Polyclonal Antibody Production Rabbits
407 01 - Polyclonal Antibody Production In Rats
408 01 - Water Control in Non-Human Primates
409 01 - Maintaining Clinical Records

 410 01 - Humane Endpoints
412 01 - Humane Endpoints for Aging Rodents
413 01 - Tissue Collection for Genotyping Rats
415 02 - Humane Endpoints for Rodent Cancer Models
Tumor Volume
Metastatic Model Monitoring log
Mammary gland identification mouse
Tumor Monitoring Log 


Animal Care

501 01 - Animal Transport and Use Outside of Facilities

502 01 - Environmental Enrichment Program for Mice
503 01 - Environmental Enrichment Program for Rats
504 01 - Environmental Enrichment Program for Rabbits
505 01 - Environmental Enrichment Program for Hamsters
506 01 - Environmental Enrichment Program for Guinea Pigs
507 01 - Environmental Enrichment Program for Non-Human Primates

508 01 - Rodent Husbandry
509 01 - Rodent Daily Care
511 01 - Sentinel Husbandry
512 01 - Contact Sentinel Husbandry
513 01 - Marmoset Husbandry
514 01 - Marmoset Daily Care
515 01 - Marmoset Feeding
516 01 - Marmoset Cage Changing
517 01 - Marmoset Room Sanitation
519 01 - Aquatic Animal Husbandry
523 01 - Rabbit Husbandry
524 01 - Rabbit Daily Care
525 01 - Cat Husbandry
526 01 - Cat Daily Care
531 01 - Animal Acquisition, Receiving, and Acclimation 


Veterinary Care

601 02 - Rodent Veterinary Care Program
602 02 - Rodent Health Monitoring Program
603 01 - Rodent Quarantine Program
604 02 - Bioexclusion Levels for Rodents
610 01 - Testing of Biological Material
615 02 - Post Irradiation Care 


Occupational Health and Safety

701 01 - Macaque Related Injury
705 01 - Animal Biosafety Level 2 Rodents
708 02 - Use of Streptozotocin in Rodents
710-01 - Personal Protective Equipement Requirements 


Other SOPs:

Xenopus Frog Surgery for Oocytes Removal - SOP#9

SOP #9 - Xenopus Frog Surgery for Oocytes Removal

Body Condition Score (BCS)

Body Condition Score Outline Mice
Body Condition Score Outline For Rats
Cow Body Condition Score

Of interest:

Article Body Condition Score for Rats

Veterinary Care SOP #014 for Long Term Housing

SOP #014 - Long-term Housing

SOPs related to animal facility maintenance:

SOP C-3 - Procedure Room Maintenance
SOP C-2 - Working with a Laminar Flow Cabinet

 

Draft SOPs for review by all.

 

Please send your comments to animalcare [at] mcgill [dot] ca (this email )by March 31st so that they are up for approval at April 2013 meeting (was January but more time was given for input from community):

101-rodent_analgesia-draft-nov2012.doc

102-rabbit_analgesia-draft-nov2012.doc 

103-nhp_analgesia-draft-nov2012.doc

104-dog_analgesia-draft-nov2012.doc

105-cat_analgesia_2-draft-nov2012.doc

106-swine_analgesia-draft-nov2012.doc

108-fish_amphibian_reptile_analgesia_2-draft-nov2012.doc 

109-ruminant_analgesia-draft-nov2012.doc

110-mouse_anesthesia-draft-nov2012.doc 

116-dog_anesthesia-draft-nov2012.doc

117-cat_anesthesia_2-draft-nov2012.doc 

119-swine_anesthesia-draft-nov2012.doc