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 Prostaglandin F2α - induced cell ruffling, shown by phalloidin staining, can be inhibited by PDC113.824 (structure shown)

Confocal microscopy image of a rat spinal cord Lamina I neuron labelled retrogradely from the parabrachial nucleus with cholera toxin subunit b (CTb - in red) which displays substance P receptor (NK-1r) immunoreactivity (in green) on the plasma membrane.

Alfredo Ribeiro-da-Silva

Clostridium difficile causes serious nosocomial infections of the colon. Two toxins secreted by the bacteria are interesting therapeutic targets. 2014, CDC, Photo credit: Jennifer Hulsey

Bastien Castagner

3D reconstruction of pathologic neo-vessels(red) and retinal ganglion cell(green) at post-natal day 17 in a model of human ocular neovascular disease

The Department has interests in both basic and clinical areas of research, although its emphasis is on the basic sciences. The Department is constantly adding to its expertise by attracting new or affiliated members to its growing staff. With 47 full or affiliated faculty members, the repertoire of its research specialties includes neuropharmacology, reproductive, endocrine, receptor, cardiovascular, cancer, developmental, clinical and biochemical pharmacology, molecular biology, proteomics, genomics, epigenomics and toxicology.