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Institute of Parasitology Publications 2012

Accardi, MV, Beech, RN and Forrester, SG (2012)
Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics. Invertebrate neuroscience 12 3-12.
Barrere, V, Alvarez, L, Suarez, G, Ceballos, L, Moreno, L, Lanusse, C and Prichard, RK (2012)
Relationship between increased albendazole systemic exposure and changes in single nucleotide polymorphisms on the beta-tubulin isotype 1 encoding gene in Haemonchus contortus. Veterinary parasitology 186 344-9.
Basanez, MG, McCarthy, JS, French, MD, Yang, GJ, Walker, M, Gambhir, M, Prichard, RK and Churcher, TS (2012)
A research agenda for helminth diseases of humans: modelling for control and elimination. PLoS neglected tropical diseases 6 e1548.
Boatin, BA, Basanez, MG, Prichard, RK, Awadzi, K, Barakat, RM, Garcia, HH, Gazzinelli, A, Grant, WN, McCarthy, JS, N'Goran, EK, Osei-Atweneboana, MY, Sripa, B, Yang, GJ and Lustigman, S (2012)
A research agenda for helminth diseases of humans: towards control and elimination. PLoS neglected tropical diseases 6 e1547.
Boitz, JM, Strasser, R, Hartman, CU, Jardim, A and Ullman, B (2012)
Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism. The Journal of biological chemistry 287 7626-39.
Boitz, JM, Ullman, B, Jardim, A and Carter, NS (2012)
Purine salvage in Leishmania: complex or simple by design? Trends in parasitology 28 345-52.
Cotton, S, Donnelly, S, Robinson, MW, Dalton, JP and Thivierge, K (2012)
Defense peptides secreted by helminth pathogens: antimicrobial and/or immunomodulator molecules? Front Immunol 3 269.
Dalton, JP, Demanga, CG, Reiling, SJ, Wunderlich, J, Eng, JW and Rohrbach, P (2012)
Large-scale growth of the Plasmodium falciparum malaria parasite in a wave bioreactor. International journal for parasitology 42 215-20.
Demanga, C, Eng, J and Dalton, JP (2012)
A novel method for lagre-scale culture of Plasmodium falciparum asexual blood stage and gametocytes in a wave biorecator cell culture system. Malaria Journal 11 22.
El-Shehabi, F, Taman, A, Moali, LS, El-Sakkary, N and Ribeiro, P (2012)
A novel G protein-coupled receptor of Schistosoma mansoni (SmGPR-3) is activated by dopamine and is widely expressed in the nervous system. PLoS neglected tropical diseases 6 e1523.
Geary, J, Satti, M, Moreno, Y, Madrill, N, Whitten, D, Headley, SA, Agnew, D, Geary, T and Mackenzie, C (2012)
First analysis of the secretome of the canine heartworm, Dirofilaria immitis. Parasit Vectors 5 140.
Geary, T and Ubalijoro, E (2012)
Searching for drugs that target multiple receptors for anthelmintics from African natural products. In: Drug Discovery in Africa . Eds Chibale, K, Davies-Coleman, M and Masimirembwa, C, Germany, Springer-Verlag. Ch 6 127-150.
Geary, TG (2012)
Are new anthelmintics needed to eliminate human helminthiases? Current opinion in infectious diseases 25 709-17.
Geary, TG (2012)
Mechanism-based screening strategies for anthelmintic discovery. In: Parasitic Helminths: Targets, Screens, Drugs and Vaccines . Eds Caffrey, C, Germany, Wiley-VCH Verlag. Ch 8 123-134.
Geary, TG, Chibale, K, Abegaz, B, Andrae-Marobela, K and Ubalijoro, E (2012)
A new approach for anthelmintic discovery for humans. Trends in parasitology 28 176-81.
Geary, TG and Gauvry, N (2012)
Anthelmintic discovery for human infections. In: Neglected Diseases and Drug Discovery . Eds Palmer, M and Wells, T, Cambridge, UK, The Ropal Society of Chemistry Press. Ch 11 290-321.
Geary, TG and Moreno, Y (2012)
Macrocyclic lactone anthelmintics: spectrum of activity and mechanism of action. Current pharmaceutical biotechnology 13 866-72.
Gheorghiu, C, Marcogliese, DJ and Scott, ME (2012)
Waterborne zinc alters temporal dynamics of guppy Poecilia reticulata epidermal response to Gyrodactylus turnbulli (Monogenea). Dis Aquat Organ 98 143-53.
Goodarzi, H, Najafabadi, HS, Oikonomou, P, Greco, TM, Fish, L, Salavati, R, Cristea, IM and Tavazoie, S (2012)
Systematic discovery of structural elements governing stability of mammalian messenger RNAs. Nature 485 264-8.
Guo, Q, Reiling, SJ, Rohrbach, P and Ma, H (2012)
Microfluidic biomechanical assay for red blood cells parasitized by Plasmodium falciparum. Lab on a chip 12 1143-50.
Halpenny, CM, Koski, KG, Valdes, VE and Scott, ME (2012)
Prediction of child health by household density and asset-based indices in impoverished indigenous villages in rural Panama. The American journal of tropical medicine and hygiene 86 280-91.
Hongoh, V, Berrang-Ford, L, Scott, ME and Lindsay, L (2012)
Expanding geographical distribution of the mosquito, Culex pipiens, in Canada under climate change. Applied Geography 33 53-62.
Kala, S, Moshiri, H, Mehta, V, Yip, CW and Salavati, R (2012)
The oligonucleotide binding (OB)-fold domain of KREPA4 is essential for stable incorporation into editosomes. PloS one 7 e46864.
Loaiza, JR, Bermingham, E, Sanjur, OI, Scott, ME, Bickersmith, SA and Conn, JE (2012)
Review of genetic diversity in malaria vectors (Culicidae: Anophelinae). Infect Genet Evol 12 1-12.
Lustigman, S, Prichard, RK, Gazzinelli, A, Grant, WN, Boatin, BA, McCarthy, JS and Basanez, MG (2012)
A research agenda for helminth diseases of humans: the problem of helminthiases. PLoS neglected tropical diseases 6 e1582.
Martin, RJ, Robertson, AP, Buxton, SK, Beech, RN, Charvet, CL and Neveu, C (2012)
Levamisole receptors: a second awakening. Trends in parasitology 28 289-96.
McCarthy, JS, Lustigman, S, Yang, GJ, Barakat, RM, Garcia, HH, Sripa, B, Willingham, AL, Prichard, RK and Basanez, MG (2012)
A research agenda for helminth diseases of humans: diagnostics for control and elimination programmes. PLoS neglected tropical diseases 6 e1601.
McVeigh, P, Maule, AG, Dalton, JP and Robinson, MW (2012)
Fasciola hepatica virulence-associated cysteine peptidases: a systems biology perspective. Microbes and infection / Institut Pasteur 14 301-10.
Menez, C, Sutra, JF, Prichard, R and Lespine, A (2012)
Relative neurotoxicity of ivermectin and moxidectin in Mdr1ab (-/-) mice and effects on mammalian GABA(A) channel activity. PLoS neglected tropical diseases 6 e1883.
Nana-Djeunga, H, Bourguinat, C, Pion, SD, Kamgno, J, Gardon, J, Njiokou, F, Boussinesq, M and Prichard, RK (2012)
Single nucleotide polymorphisms in beta-tubulin selected in Onchocerca volvulus following repeated ivermectin treatment: possible indication of resistance selection. Molecular and biochemical parasitology 185 10-8.
Osei-Atweneboana, MY, Boakye, D, Awadzi, K, Gyapong, J and Prichard, R (2012)
Genotypic analysis of beta-tubulin in Onchocerca volvulus from communities and individuals showing poor parasitological response to ivermectin treatment. International Journal for Parasitology: Drugs and Drug Resistance 2 20-28.
Osei-Atweneboana, MY, Lustigman, S, Prichard, RK, Boatin, BA and Basanez, MG (2012)
A research agenda for helminth diseases of humans: health research and capacity building in disease-endemic countries for helminthiases control. PLoS neglected tropical diseases 6 e1602.
Patocka, N and Ribeiro, P (2013)
The functional role of a serotonin transporter in Schistosoma mansoni elucidated through immunolocalization and RNA interference (RNAi). Molecular and biochemical parasitology 187 32-42.
Perez-Jvostov, F, Hendry, AP, Fussmann, GF and Scott, ME (2012)
Are host-parasite interactions influenced by adaptation to predators? A test with guppies and Gyrodactylus in experimental stream channels. Oecologia 170 77-88.
Poreba, M, McGowan, S, Skinner-Adams, TS, Trenholme, KR, Gardiner, DL, Whisstock, JC, To, J, Salvesen, GS, Dalton, JP and Drag, M (2012)
Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum. PloS one 7 e31938.
Prichard, R, Menez, C and Lespine, A (2012)
Moxidectin and the avermectins: Consaguinity but not identity. International Journal for Parasitology: Drugs and Drug Resistance 2 134-153.
Prichard, RK, Basanez, MG, Boatin, BA, McCarthy, JS, Garcia, HH, Yang, GJ, Sripa, B and Lustigman, S (2012)
A research agenda for helminth diseases of humans: intervention for control and elimination. PLoS neglected tropical diseases 6 e1549.
Reiling, SJ and Rohrbach, P (2012)
Maurer's clefts of Plasmodium falciparum: Unraveling its morphology. In: Plasmodium falciparum . Eds Mayer, G, Nova Science Publishers. Ch 99-122.
Ribeiro, P, Gupta, V and El-Sakkary, N (2012)
Biogenic amines and the control of neuromuscular signaling in schistosomes. Invertebrate neuroscience : IN 12 13-28.
Robinson, MW, Alvarado, R, To, J, Hutchinson, AT, Dowdell, SN, Lund, M, Turnbull, L, Whitchurch, CB, O'Brien, BA, Dalton, JP and Donnelly, S (2012)
A helminth cathelicidin-like protein suppresses antigen processing and presentation in macrophages via inhibition of lysosomal vATPase. FASEB J 26 4614-27.
Robinson, MW, Dalton, JP, O'Neill, S and Donnelly, S (2012)
Mechanisms of immune modulation by Fasciola hepatica: importance for vaccine development and for novel immunotherapetics. In: Parasitic Helminths: Targets, Screens, Drugs and Vaccines . Eds Caffrey, C, Germany, Wiley-VCH Verlag. Ch 27 451-463.
Rohrbach, P (2012)
Quantitative fluorescent live cell imaging of intracellular Ca2+ and H+ ions in malaria parasites. Methods in enzymology 505 469-83.
Salavati, R, Moshiri, H, Kala, S and Najafabadi, HS (2012)
Inhibitors of RNA editing as potential chemotherapeutics against trypanosomatid pathogens. International Journal for Parasitology: Drugs and Drug Resistance 2 36-46.
Sivaraman, KK, Oellig, CA, Huynh, K, Atkinson, SC, Poreba, M, Perugini, MA, Trenholme, KR, Gardiner, DL, Salvesen, G, Drag, M, Dalton, JP, Whisstock, JC and McGowan, S (2012)
X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase PfM18AAP. Journal of molecular biology 422 495-507.
Skinner-Adams, TS, Peatey, CL, Anderson, K, Trenholme, KR, Krige, D, Brown, CL, Stack, C, Nsangou, DM, Mathews, RT, Thivierge, K, Dalton, JP and Gardiner, DL (2012)
The aminopeptidase inhibitor CHR-2863 is an orally bioavailable inhibitor of murine malaria. Antimicrobial agents and chemotherapy 56 3244-9.
Vercruysse, J, Albonico, M, Behnke, JM, Kotze, AC, Prichard, RK, McCarthy, JS, Montresor, A and Levecke, B (2011)
Is anthelmintic resistance a concern for the control of human soil-transmitted helminths? International Journal for Parasitology: Drugs and Drug Resistance 1 14-27.
Vercruysse, J, Levecke, B and Prichard, R (2012)
Human soil-transmitted helminths: implications of mass drug administration. Current opinion in infectious diseases 25 703-8.
Wang, XR, Moreno, YA, Wu, HR, Ma, C, Li, YF, Zhang, JA, Yang, C, Sun, S, Ma, WJ and Geary, TG (2012)
Proteomic profiles of soluble proteins from the esophageal gland in female Meloidogyne incognita. International journal for parasitology 42 1177-83.
Woods, D, Maeder, S, Robertson, AP, Martin, RJ, Geary, T, Thompson, D, Johnson, S and Conder, G (2012)
Discovery, mode of action and commercialization of Derquantel. In: Parasitic Helminths: Targets, Screens, Drugs and Vaccines . Eds Caffrey, C, Germany, Wiley-VCH Verlag. Ch 18 297-307.
Wunderlich, J, Rohrbach, P and Dalton, JP (2012)
The malaria digestive vacuole. Front Biosci (Schol Ed) 4 1424-48.
Yan, R, Urdaneta-Marquez, L, Keller, K, James, CE, Davey, MW and Prichard, RK (2012)
The role of several ABC transporter genes in ivermectin resistance in Caenorhabditis elegans. Veterinary parasitology 190 519-29.
Yang, Y, Li, Z, Mo, W, Ambadipudi, R, Arnold, RJ, Hrncirova, P, Novotny, MV, Georges, E and Zhang, JT (2012)
Human ABCC1 interacts and colocalizes with ATP synthase alpha, revealed by interactive proteomics analysis. Journal of proteome research 11 1364-72.