Armando Jardim - Publications

van Bergen B, Cyr N, Strasser R, Blanchette M, Sheppard JD, Jardim A. (2016) α,β-Dicarbonyl reduction is mediated by the Saccharomyces Old Yellow Enzyme. FEMS Yeast Res. (in press)

Smith S, Boitz J, Chidambaram ES, Chatterjee A, Ait-Tihyaty M, Ullman B, Jardim A. (2015) The cystathionine-β-synthase domains on the guanosine 5''-monophosphate reductase and inosine 5'-monophosphate dehydrogenase enzymes from Leishmania regulate enzymatic activity in response to guanylate and adenylate nucleotide levels. Mol Microbiol. 100:824-40

Chatterjee A, Caballero-Franco C, Bakker D, Totten S, Jardim A. (2015) Pore-forming Activity of the Escherichia coli Type III Secretion System Protein EspD.. J Biol Chem. 290:25579-94

Valanparambil RM, Segura M, Tam M, Jardim A, Geary TG and Stevenson MM (2014) Production and analysis of immunomodulatory excretory-secretory products from the mouse gastrointestinal nematode Heligmosomoides polygyrus bakeri. Nat Protoc 9: 2740-54.

Pilar AV, Strasser R, McLean J, et al. (2014) Analysis of the Leishmania peroxin 7 interactions with peroxin 5, peroxin 14 and PTS2 ligands. Biochem J 460: 273-82.

Hojjat H and Jardim A (2014) Identification of Leishmania donovani Peroxin 14 Residues Required for Binding the Peroxin 5 Receptor Proteins. Biochem J

Jardim AC, Bittar C, Matos RP, et al. (2013) Analysis of HCV quasispecies dynamic under selective pressure of combined therapy. BMC Infect Dis 13: 61.

Boitz JM, Strasser R, Yates PA, Jardim A and Ullman B (2013) Adenylosuccinate synthetase and adenylosuccinate lyase deficiencies trigger growth and infectivity deficits in Leishmania donovani. J Biol Chem 288: 8977-90.

Lakhal-Naouar I, Jardim A, Strasser R, et al. (2012) Leishmania donovani argininosuccinate synthase is an active enzyme associated with parasite pathogenesis. PLoS Negl Trop Dis 6: e1849.

Boitz JM, Ullman B, Jardim A and Carter NS (2012) Purine salvage in Leishmania: complex or simple by design? Trends Parasitol 28: 345-52.

Boitz JM, Strasser R, Hartman CU, Jardim A and Ullman B (2012) Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism. J Biol Chem 287: 7626-39.

Hassani K, Antoniak E, Jardim A and Olivier M (2011) Temperature-induced protein secretion by Leishmania mexicana modulates macrophage signalling and function. PLoS One 6: e18724.

Fulwiler AL, Boitz JM, Gilroy C, Yates PA, Jardim A and Ullman B (2011) IMP dehydrogenase deficiency in Leishmania donovani causes a restrictive growth phenotype in promastigotes but is not essential for infection in mice. Mol Biochem Parasitol 180: 123-6.

Feng X, Feistel T, Buffalo C, et al. (2011) Remodeling of protein and mRNA expression in Leishmania mexicana induced by deletion of glucose transporter genes. Mol Biochem Parasitol 175: 39-48.

Dasanayake D, Richaud M, Cyr N, et al. (2011) The N-terminal amphipathic region of the Escherichia coli type III secretion system protein EspD is required for membrane insertion and function. Mol Microbiol 81: 734-50.

Ullman B, Cyr N, Choi K and Jardim A (2010) Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase. Int J Biochem Cell Biol 42: 253-62.

Ullman B, Cyr N, Choi K and Jardim A (2010) Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase. Int J Biochem Cell Biol 42: 253-62.

Sethadavit M, Meemon K, Jardim A, Spithill TW and Sobhon P (2009) Identification, expression and immunolocalization of cathepsin B3, a stage-specific antigen expressed by juvenile Fasciola gigantica. Acta Trop 112: 164-73.

El Fadili K, Drummelsmith J, Roy G, Jardim A and Ouellette M (2009) Down regulation of KMP-11 in Leishmania infantum axenic antimony resistant amastigotes as revealed by a proteomic screen. Exp Parasitol 123: 51-7.

Pilar AV, Madrid KP and Jardim A (2008) Interaction of Leishmania PTS2 receptor peroxin 7 with the glycosomal protein import machinery. Mol Biochem Parasitol 158: 72-81.

Cyr N, Madrid KP, Strasser R, et al. (2008) Leishmania donovani peroxin 14 undergoes a marked conformational change following association with peroxin 5. J Biol Chem 283: 31488-99.