Robin Beech - Publications

Blanchard A, Gégnard F, Charvet C, et al. (2018) Deciphering anthelmintic targets from parasitic nematodes: when the model becomes the exception. PLOS Pathogens Submitted:

Kaur S, Dhugga KS, Beech R and Singh J (2017) Genome-wide analysis of the cellulose synthase-like (Csl) gene family in bread wheat (Triticum aestivum L.). BMC Plant Biol 17: 193.

Ishii J, Arenal A, Felix A, Yoshitani U, Beech R and Molento M (2017) Diagnosis of resistance alleles in codon 167 of the beta-tubulin (Cya-tbb-1) gene from third-stage larvae of horse cyathostomins. Research in Veterinary Science 115: 92-95.

International Helminth Genomes Consortium (2017) Comparative genomics of the major parasitic worms. bioRxiv

Godoy P, Che H, Beech RN and Prichard RK (2016) Characterisation of P-glycoprotein-9.1 in Haemonchus contortus. Parasite Vectors 9: 52.

Duguet TB, Charvet CL, Forrester SG, et al. (2016) Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. PLoS Negl Trop Dis 10: e0004826.

Ashraf S, Beech RN, Hancock MA and Prichard RK (2015) Ivermectin binds to Haemonchus contortus tubulins and promotes stability of microtubules. Int J Parasitol 

Ashraf S, Mani T, Beech R and Prichard R (2015) Macrocyclic lactones and their relationship to the SNPs related to benzimidazole resistance. Molecular and Biochemical Parasitology 201: 128-134.

Beech RN and Neveu C (2015) The evolution of pentameric ligand-gated ion-channels and the changing family of anthelmintic drug targets. Parasitology 142: 303-17.

Baur R, Beech RN, Sigel E and Rufener L (2015) Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 and Caenorhabditis elegans ACR-20 receptors. Molecular Pharmacology 87: 96-102.

Courtot E, Charvet CL, Beech RN, et al. (2015) Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes. PLoS Pathogens 11: e1005267.

Godoy P, Che H, Beech RN and Prichard RK (2015) Characterization of Haemonchus contortus P-glycoprotein-16 and its interaction with the macrocyclic lactone anthelmintics. Molecular and Biochemical Parasitology 204: 11-15.

Godoy P, Lian J, Beech RN and Prichard RK (2015) Haemonchus contortus P-glycoprotein-2: in situ localisation and characterisation of macrocyclic lactone transport. International Journal for Parasitology 45: 85-93.

Lynagh T, Beech RN, Lalande MJ, et al. (2015) Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels. Sci Rep 5: 8558.

Rostami S, Salavati R, Beech RN, Babaei Z, Sharbatkhori M and Harandi MF (2015) Genetic variability of Taenia saginata inferred from mitochondrial DNA sequences. Parasitology Research 114: 1365-76.

Urdaneta L, Beech R, Dent J and Prichard R (2014) A dyf-7 haplotype causes sensory neuron defects and is associated with macrocyclic lactone resistance worldwide in the nematode parasite Haemonchus contortus. International Journal for Parasitology 44: 1063-71.

Kotze A, Hunt P, Skuce P, et al. (2014) Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug / receptor interactions. International Journal for Parasitology Drugs and Drug Resistance 4: 164-84.

Issouf M, Guegnard F, Koch C, et al. (2014) Haemonchus contortus P-glycoproteins interact with host eosinophil granules: a novel insight into the role of ABC transporters in host-parasite interaction. PLoS One 9: e87802.

Barrere V, Beech RN, Charvet CL and Prichard RK (2014) Novel assay for the detection and monitoring of levamisole resistance in Haemonchus contortus. Int J Parasitol 44: 235-41.

Saunders GI, Wasmuth JD, Beech RN, et al. (2013) Characterization and comparative analysis of the complete Haemonchus contortus beta-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes. International journal for parasitology 43: 465-75.

Rufener L, Bedoni N, Baur R, et al. (2013) acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans. PLoS pathogens 9: e1003524.

Rostami S, Salavati R, Beech RN, et al. (2013) Cytochrome c oxidase subunit 1 and 12S ribosomal RNA characterization of Coenurus cerebralis from sheep in Iran. Vet Parasitol 197: 141-51.

Rostami S, Salavati R, Beech RN, et al. (2013) Molecular and morphological characterization of the tapeworm Taenia hydatigena (Pallas, 1766) in sheep from Iran. J Helminthol 1-8.

Rostami S, Beech RN, Salavati R, Baneshi M, Kamyabi H and Fasihi Harandi M (2013) Morphometric analysis of larval rostellar hooks in Taenia multiceps of sheep in Iran and its association with mitochondrial gene variability. Iranian Journal of Parasitology 8: 579-85.

Laing R, Kikuchi T, Martinelli A, et al. (2013) The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery. Genome biology 14: R88.

Dufour V, Beech RN, Wever C, Dent JA and Geary TG (2013) Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni. PLoS pathogens 9: e1003586.

Beech RN, Callanan MK, Rao VT, Dawe GB and Forrester SG (2013) Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes. Parasitol Int 62: 599-605.

Martin RJ, Robertson AP, Buxton SK, Beech RN, Charvet CL and Neveu C (2012) Levamisole receptors: a second awakening. Trends in parasitology 28: 289-96.

Accardi MV, Beech RN and Forrester SG (2012) Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics. Invertebrate neuroscience 12: 3-12.

Laing R, Hunt M, Protasio AV, et al. (2011) Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. PLoS One 6: e23216.

Beech RN, Skuce P, Bartley DJ, Martin RJ, Prichard RK and Gilleard JS (2011) Anthelmintic resistance: markers for resistance, or susceptibility? Parasitology 138: 160-74.

Rao VT, Accardi MV, Siddiqui SZ, Beech RN, Prichard RK and Forrester SG (2010) Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus. Molecular and biochemical parasitology 173: 64-8.

Neveu C, Charvet CL, Fauvin A, Cortet J, Beech RN and Cabaret J (2010) Genetic diversity of levamisole receptor subunits in parasitic nematode species and abbreviated transcripts associated with resistance. Pharmacogenetics and genomics 20: 414-25.

Beech RN, Zarlenga D, Bird D, Berriman M and Dent JA (2010) Naming genes beyond Caenorhabditis. Worm Breeder's Gazette 18: 17.

Beech RN, Wolstenholme AJ, Neveu C and Dent JA (2010) Nematode parasite genes: what's in a name? Trends in parasitology 26: 334-40.

Beech RN and Sylvestre A (2010) Mutations associated with anthelmintic drug resistance. Anti-Inf Agent Med Chem 9: 105-112.

Beech RN, Levitt N, Cambos M, Zhou S and Forrester SG (2010) Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus. Molecular and biochemical parasitology 171: 74-80.

Morissette DC, Dauch A, Beech RN, Masson L, Brousseau R and Jabaji-Hare S (2008) Isolation of mycoparasitic-related transcripts by SSH during interaction of the mycoparasite Stachybotrys elegans with its host Rhizoctonia solani. Current genetics 53: 67-80.

Blackhall WJ, Prichard RK and Beech RN (2008) P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles. Veterinary parasitology 152: 101-7.

Jia X, Ebine N, Demonty I, et al. (2007) Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 transporter expressions in hamsters. The British journal of nutrition 98: 550-5.

Gilleard JS and Beech RN (2007) Population genetics of anthelmintic resistance in parasitic nematodes. Parasitology 134: 1133-47.

Eng JK, Blackhall WJ, Osei-Atweneboana MY, et al. (2006) Ivermectin selection on beta-tubulin: evidence in Onchocerca volvulus and Haemonchus contortus. Molecular and biochemical parasitology 150: 229-35.

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