Clinical Interests
Hip and Knee Reconstruction
Research Interests
Outcome of total hip arthroplasty
Periprosthetic osteolysis
Wear debris and metal ions
Current Appointments
Assistant Professor of Surgery, Division of Orthopaedic Surgery, McGill University
Staff Orthopaedic Surgeon, SMBD - Jewish General Hospital
Consulting Staff Orthopaedic Surgeon, Jewish Rehabilitation Hospital
Undergraduate Studies
1977-1980 B.Sc., Honors Physiology, McGill University
Medical School
1980-1985 McGill University
Residency
1986-1990 Programme d'Orthopédie Édouard-Samson, Université de Montréal
Fellowship
1990-1991 Orthopaedic Surgery Clinical Fellowship, Hôtel-Dieu de Montréal, Université de Montréal
1991-1992 Hip Arthroplasty Fellowship, Hospital for Special Surgery, Cornell University Medical College
Other Graduate Studies
1985-1986 M.Sc., Clinical Sciences, Université de Montréal
Grants Held in Last 5 Years
Canadian Orthopaedic Foundation
Serum metal ion levels in patients with metal-on-metal prostheses
J Antoniou, A Petit, T Ahmedali, DJ Zukor, OL Huk
$10,000 / 2005-2006
Current Address
SMBD-Jewish General Hospital, Room E-003
3775 chemin Côte Ste-Catherine
Montreal, QC
H3T 1E2
Telephone: (514) 340-8222 est. 3605
Fax: (514) 340-7595
ohuk [at] ldi.jgh.mcgill.ca
Recent Publications
- SG Bergeron, M Bernstein, A Petit, OL Huk, J Antoniou. Rise of cobalt and chromium ion levels in patients undergoing bilateral hip resurfacings. Clin Orthop Relat Res. In press.
- NM Desy, SG Bergeron, A Petit, OL Huk, J Antoniou. The influence of surgical variables on metal ion levels after hip resurfacing. Clin Orthop Relat Res. In press.
- C Tkaczyk, OL Huk, F Mwale, J Antoniou, DJ Zukor, A Petit, M Tabrizian. Investigation of the intercaction of Cr(III) complexes with bovine and human serum proteins: A proteomic approach. Biomaterials. J Biomed Mater Res Part A. 94-A: 214-222, 2010.
- C Tkaczyk, OL Huk, F Mwale, J Antoniou, DJ Zukor, A Petit, M Tabrizian. Effect of metal ions on the expression of antioxidant enzymes in human U937 macrophage-like cells. J Biomed Mater Res – Part A. 94-A: 419-425, 2010.
- C Tkaczyk, M Tabrizian, J Antoniou, DJ Zukor, A Petit, OL Huk. Significance of elevated blood metal ion levels in patients with metal-on-metal prostheses: an evaluation of oxidative stress markers. The Open Orthop J. 4: 188-194, 2010.
- C Tkaczyk, OL Huk, F Mwale, J Antoniou, DJ Zukor, A Petit, M Tabrizian. The molecular structure of complexes formed by chromium or cobalt ions in simulated physiological fluids. Biomaterials. 30: 460-467, 2009.
- S Bergeron, KJ Kardash, OL Huk, DJ Zukor, J Antoniou. The long-term functional outcome of femoral versus obturator nerve block following total knee replacement. Clin Orthop Relat Res. 467: 1458-1462, 2009.
- S Bergeron, KJ Kardash, OL Huk, DJ Zukor, J Antoniou. The long-term functional outcome after a single perioperative dose of dexamethasone in total hip arthroplasty. Clin Orthop Relat Res. 467: 1463-1467, 2009.
- VS Nikolaou, SG Bergeron, OL Huk, DJ Zukor, J Antoniou. Evaluation of persistent pain after hip resurfacing. Bull NYU Hospital for Joint Dis. 67: 168-172, 2009.
- C Tkaczyk, OL Huk, F Mwale, J Antoniou, DJ Zukor, A Petit, M Tabrizian. The molecular structure of complexes formed by chromium or cobalt ions in simulated physiological fluids. Biomaterials. 30: 460-467, 2009.
- CJ Richards, D Giannitsios, OL Huk, DJ Zukor, T Steffen, J Antoniou. Risk of periprosthetic femoral neck fracture after hip resurfacing arthroplasty: Valgus compared with anatomic alignment. A biomechanical and clinical analysis. J Bone Joint Surg [Am]. 90-A (Suppl 3): 96-101, 2008.
- J Antoniou, DJ Zukor, F Mwale, W Minarik, A Petit, OL Huk. Metal ion levels in the blood of patients after hip resurfacing: A comparison between twenty-eight and thirty-six millimeter-head metal-on-metal prostheses. J Bone Joint Surg [Am]. 90-A (Suppl 3): 142-148, 2008.
- F Mwale, HT Wang, DJ Zukor, OL Huk, A Petit, J Antoniou. Effect of a type II collagen fragment on the expression of genes of the extracellular matrix in cells of the intervertebral disc. The Open Orthop J. 2: 1-9, 2008.
- A Petit, F Mwale, C Tkaczyk, J Antoniou, DJ Zukor, OL Huk. Cobalt and chromium ions induce nitration of proteins in human U937 macrophages in vitro. J Biomed Mater Res – Part A. 79A: 599-605, 2006.
- I Catelas, P Campbell, JD Bobyn, JB Medley, OL Huk. Wear particles from metal-on-metal total hip replacements: effects of implant design and implantation time. Proc IMechE - Part H J Eng Med. 220 (Special Issue), 195-208, 2006.
- C Fleury, A Petit, F Mwale, J Antoniou, DJ Zukor, M Tabrizian, OL Huk. Effect of cobalt and chromium ions on human MG-63 osteoblasts in vitro: morphology, cytotoxicity, and oxidative stress. Biomaterials. 27: 3351-3360, 2006.
- A Petit, F Mwale, DJ Zukor, J Antoniou, OL Huk. Effect of bisphosphonates on the stimulation of macrophage by alumina ceramic particles: a comparison with ultra-high-molecular-weight polyethylene. J Mater Sci: Mater Med. 17: 667-673, 2006.