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Estimation of fetal macrosomia among the James Bay Cree

Macrosomia is associated with significant perinatal morbidity and its' definition is based on primarily Caucasian standards.  Once macrosomia is identified or predicted, obstetrical decisions or interventions are made which in turn can be associated with different maternal, fetal and neonatal morbidity.  Thus the definition of macrosmia is important. The James Bay Cree are at risk of increased GDM, increased macrosomia, and consequently, increased interventions (inductions/ cesareaqn sections), which may or may not be appropriate depending on the appropriateness of the definition of macrosomia for this particulaar population.

This study involves a retrospective cross sectional chart/lab/ultrasound review of 4000 Cree women with singleton pregnancies who had ultrasound at the Vald'Or hospital or who were transferred to the MUHC of St Justine Hospital between 2000-2010, as well as 120,00 non-Cree women from 2008-2010 from an existing database.

Objectives

  1. Develop fetal growth charts and birthweight charts specific to the eastern James Bay Cree population of Quebec
  2. Investigate the association between diagnosis of macrosomia and incidence of maternal interventions and perinatal complications, and propose  clinical pathways that could guide standards of care.

Funded by Canadian Institute of Health Research

Principal co-investigator: Nils Chaillet, PhD and Zhong-Cheng Luo, PhD, University of Montreal

Co-investigators: Jean-Luc Ardilouze, CHUS; Fracois Audibert, CHSJ; Louise Duperron, CHSJ;  Robert Gagnon, MUHC profile; Line Leduc CHSJ; Alexandrov Lubomir, CHSJ; Marie-Eve mathieu, CHSJ; Patricia Monnier, MUHC profile; Vyta Senikas, SOGC; Manon Turbide, CH Val d'Or.