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epigenetics

The father effect

A father's behavior and environment before his children are even conceived may affect the health of his children and grandchildren

Discovery of how environmental memories may be transmitted from a man to his grandchildren

Published: 8Oct2015

Honey, I shrunk the ants: how environment controls size

Until now scientists have believed that the variations in traits such as our height, skin colour, tendency to gain weight or not, intelligence, tendency to develop certain diseases, etc., all of them traits that exist along a continuum, were a result of both genetic and environmental factors. But they didn’t know how exactly these things worked together. By studying ants, McGill researchers have identified a key mechanism by which environmental (or epigenetic) factors influence the expression of all of these traits, (along with many more).

Published: 11Mar2015

How do environments talk to genes?

A report elucidates the widely recognized, but poorly understood, concept of gene-environment interaction, finding a molecular mechanism in the case of post-traumatic stress disorder: demethylation of a glucocorticoid response element in the stress response regulator FKBP5 that depends on both the risk allele and childhood trauma. [Review on epigenetics and childhood trauma by McGill's Moshe Szyf.]

Read more at Nature Neuroscience

Published: 10Jan2013