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The Muscle Physiology and Biophysics Laboratory focuses on the molecular and cellular mechanisms of muscle contraction and force regulation in health and disease.

The laboratory studies muscle contraction on different scales such as single cells, myofibrils, sarcomeres, filaments, and motor proteins. The laboratory also designs and develops research instruments and experimental systems that are unique.

The laboratory uses advanced microscopy and micro/nano fabrication technologies to measure muscle forces ranging from millinewtons to piconewtons.

Electron microscopy images with myosin filaments: