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Journal Articles

1. D'Antoni ML, Risse PA, Ferraro P, Martin JG, Ludwig MS. (2012). Effects of decorin and biglycan on human airway smooth muscle cell adhesion. Matrix Biol. 31(2):101-12.

2. Webb, D.J. & Brown, C.M. in Neurohistology and Imaging: Basic Techniques, . (eds. R. Doucette & W. Wolfgang)2011).

3. Lacoste, J., Vining, C., Zuo, D., Spurmanis, A. & Brown, C.M. in Annual Reviews in Fluorescence 2010. (ed. C.D. Geddes)2011).

4. Cole, R.W., Jinadasa, T. & Brown, C.M. Measuring and interpreting point spread functions to determine confocal microscope resolution and ensure quality control. Nat Protoc 6, 1929-1941 (2011).

5. Zhan, Y. et al. Dystroglycan and mitochondrial ribosomal protein l34 regulate differentiation in the Drosophila eye. PLoS ONE 5, e10488 (2010).

6. Yang, W. & Hekimi, S. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol 8, e1000556 (2010).

7. Tsurudome, K. et al. The Drosophila miR-310 cluster negatively regulates synaptic strength at the neuromuscular junction. Neuron 68, 879-893 (2010).

8. Robert, R. et al. Correction of the Delta phe508 cystic fibrosis transmembrane conductance regulator trafficking defect by the bioavailable compound glafenine. Mol Pharmacol 77, 922-930 (2010).

9. Picard, M. et al. Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers. Aging Cell 9, 1032-1046 (2010).

10. Nouvion, A.L. et al. CEACAM1: a key regulator of vascular permeability. J Cell Sci 123, 4221-4230 (2010).

11. Maghzal, N., Vogt, E., Reintsch, W., Fraser, J.S. & Fagotto, F. The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling. J Cell Biol 191, 645-659 (2010).

12. LeSimple, P., Liao, J., Robert, R., Gruenert, D.C. & Hanrahan, J.W. Cystic fibrosis transmembrane conductance regulator trafficking modulates the barrier function of airway epithelial cell monolayers. J Physiol 588, 1195-1209 (2010).

13. Laplante, C., Paul, S.M., Beitel, G.J. & Nilson, L.A. Echinoid regulates tracheal morphology and fusion cell fate in Drosophila. Dev Dyn 239, 2509-2519 (2010).

14. Kugler, J.M., Woo, J.S., Oh, B.H. & Lasko, P. Regulation of Drosophila vasa in vivo through paralogous cullin-RING E3 ligase specificity receptors. Mol Cell Biol 30, 1769-1782 (2010).

15. Kugler, J.M., Lem, C. & Lasko, P. Reduced cul-5 activity causes aberrant follicular morphogenesis and germ cell loss in Drosophila oogenesis. PLoS ONE 5, e9048 (2010).

16. Khila, A. & Abouheif, E. Evaluating the role of reproductive constraints in ant social evolution. Philos Trans R Soc Lond B Biol Sci 365, 617-630 (2010).

17. Hsieh, T.C., Nicolay, B.N., Frolov, M.V. & Moon, N.S. Tuberous Sclerosis Complex 1 Regulates dE2F1 Expression during Development and Cooperates with RBF1 to Control Proliferation and Survival. PLoS Genet 6 (2010).

18. Haghayeghi, A., Sarac, A., Czerniecki, S., Grosshans, J. & Schock, F. Pellino enhances innate immunity in Drosophila. Mech Dev 127, 301-307 (2010).

19. Ball, R.W. et al. Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons. Neuron 66, 536-549 (2010).

20. Abella, J.V. et al. The Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck. J Cell Sci 123, 1306-1319 (2010).

21. Xu, Y., Benlimame, N., Su, J., He, Q. & Alaoui-Jamali, M.A. Regulation of focal adhesion turnover by ErbB signalling in invasive breast cancer cells. Br J Cancer 100, 633-643 (2009).

22. Narbonne, P. & Roy, R. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 457, 210-214 (2009).

23. Moore, J., Han, H. & Lasko, P. Bruno negatively regulates germ cell-less expression in a BRE-independent manner. Mech Dev 126, 503-516 (2009).

24. Livingstone, M., Larsson, O., Sukarieh, R., Pelletier, J. & Sonenberg, N. A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. Chem Biol 16, 1240-1249 (2009).

25. Liu, N., Han, H. & Lasko, P. Vasa promotes Drosophila germline stem cell differentiation by activating mei-P26 translation by directly interacting with a (U)-rich motif in its 3' UTR. Genes Dev 23, 2742-2752 (2009).

26. Lachance, J.F., Lomas, M.F., Eleiche, A., Kerr, P.B. & Nilson, L.A. Graded Egfr activity patterns the Drosophila eggshell independently of autocrine feedback. Development 136, 2893-2902 (2009).

27. Kugler, J.M., Chicoine, J. & Lasko, P. Bicaudal-C associates with a Trailer Hitch/Me31B complex and is required for efficient Gurken secretion. Dev Biol 328, 160-172 (2009).

28. Frigault, M.M., Lacoste, J., Swift, J.L. & Brown, C.M. Live-cell microscopy - tips and tools. J Cell Sci 122, 753-767 (2009).

29. Fagotto, F. & Brown, C.M. Detection of Nuclear beta-catenin in Xenopus Embryos. Methods Mol Biol 469, 363-380 (2009).

30. Caceres, L. & Nilson, L.A. Translational repression of gurken mRNA in the Drosophila oocyte requires the hnRNP Squid in the nurse cells. Dev Biol 326, 327-334 (2009).

31. Arsovski, A.A. et al. AtBXL1 encodes a bifunctional {beta}-D-xylosidase/{alpha}-L-arabinofuranosidase required for pectic arabinan modification in Arabidopsis thaliana mucilage secretory cells. Plant Physiol 150, 1219-1234 (2009).

32. Ursini-Siegel, J. et al. ShcA signalling is essential for tumour progression in mouse models of human breast cancer. Embo J (2008).

33. Thomson, T., Liu, N., Arkov, A., Lehmann, R. & Lasko, P. Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins. Mech Dev 125, 865-873 (2008).

34. Reintsch, W.E. & Mandato, C.A. Deciphering animal development through proteomics: requirements and prospects. Proteome Sci 6, 21 (2008).

35. Ouellet, J., Li, S. & Roy, R. Notch signalling is required for both dauer maintenance and recovery in C. elegans. Development 135, 2583-2592 (2008).

36. Lee, S., Zhou, L., Kim, J., Kalbfleisch, S. & Schock, F. Lasp anchors the Drosophila male stem cell niche and mediates spermatid individualization. Mech Dev 125, 768-776 (2008).

37. Kodiha, M., Brown, C.M. & Stochaj, U. Analysis of signaling events by combining high-throughput screening technology with computer-based image analysis. Sci Signal 1, pl2 (2008).

38. Khila, A. & Abouheif, E. Reproductive constraint is a developmental mechanism that maintains social harmony in advanced ant societies. Proc Natl Acad Sci U S A 105, 17884-17889 (2008).

39. Houssier, M. et al. CD36 deficiency leads to choroidal involution via COX2 down-regulation in rodents. PLoS Med 5, e39 (2008).

40. Hebeisen, M. & Roy, R. CDC-25.1 stability is regulated by distinct domains to restrict cell division during embryogenesis in C. elegans. Development 135, 1259-1269 (2008).

41. Hebeisen, M., Drysdale, J. & Roy, R. Suppressors of the cdc-25.1(gf)-associated intestinal hyperplasia reveal important maternal roles for prp-8 and a subset of splicing factors in C. elegans. RNA 14, 2618-2633 (2008).

42. Frigault, M.M., Naujokas, M.A. & Park, M. Gab2 requires membrane targeting and the Met binding motif to promote lamellipodia, cell scatter, and epithelial morphogenesis downstream from the Met receptor. J Cell Physiol 214, 694-705 (2008).

43. Dansereau, D.A. & Lasko, P. The development of germline stem cells in Drosophila. Methods Mol Biol 450, 3-26 (2008).

44. Dansereau, D.A. & Lasko, P. RanBPM regulates cell shape, arrangement, and capacity of the female germline stem cell niche in Drosophila melanogaster. J Cell Biol 182, 963-977 (2008).

45. Walker, V.E., Atanasiu, R., Lam, H. & Shrier, A. Co-chaperone FKBP38 promotes HERG trafficking. J Biol Chem 282, 23509-23516 (2007).

46. Ursini-Siegel, J. et al. Elevated expression of DecR1 impairs ErbB2/Neu-induced mammary tumor development. Mol Cell Biol 27, 6361-6371 (2007).

47. Lahlou, H. et al. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression. Proc Natl Acad Sci U S A 104, 20302-20307 (2007).

48. Kodiha, M., Rassi, J.G., Brown, C.M. & Stochaj, U. Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway. Am J Physiol Cell Physiol 293, C1427-1436 (2007).

49. Julien, S.G. et al. Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nat Genet 39, 338-346 (2007).

50. Jani, K. & Schock, F. Zasp is required for the assembly of functional integrin adhesion sites. J Cell Biol 179, 1583-1597 (2007).

51. Dillon, R.L., Brown, S.T., Ling, C., Shioda, T. & Muller, W.J. An EGR2/CITED1 transcription factor complex and the 14-3-3sigma tumor suppressor are involved in regulating ErbB2 expression in a transgenic-mouse model of human breast cancer. Mol Cell Biol 27, 8648-8657 (2007).

52. Combadiere, C. et al. CX3CR1-dependent subretinal microglia cell accumulation is associated with cardinal features of age-related macular degeneration. J Clin Invest 117, 2920-2928 (2007).

53. Carlile, G.W. et al. Correctors of protein trafficking defects identified by a novel high-throughput screening assay. Chembiochem 8, 1012-1020 (2007).

54. Brault, S. et al. Lysophosphatidic acid induces endothelial cell death by modulating the redox environment. Am J Physiol Regul Integr Comp Physiol 292, R1174-1183 (2007).

55. Abella JV, Peschard P, Naujokas MA, Lin T, Saucier C, Urbe S, Park M., Met/Hepatocyte growth factor receptor ubiquitination suppresses transformation and is required for Hrs phosphorylation., Mol Cell Biol. Nov;25(21):9632-45 (2005).

56. Akhavan, A., Atanasiu, R., Noguchi, T., Han, W., Holder, N. and Shrier, A., Identification of the Cyclic Nucleotide Binding Domain as a conserved determinant of ion channel cell surface localization. J. Cell Sci., 118, 2803-2812 (2005).

57. Atkey, M.R., Boisclair Lachance, J.-F., Walczak, M. and Nilson, L.A. Capicua regulates follicle cell fate in the Drosophila ovary through repression of mirror. Development, 2006, 133:2115-23.

58. Bates I.R., Hebert B., Luo Y., Liao J., Bachir A.I., Kolin D.L., Wiseman P.W., Hanrahan J.W., Membrane lateral diffusion and capture of CFTR within transient confinement zones. Biophys J. Aug 1;91(3):1046-58(2006). Epub 2006 May 19.

59. Bates I.R., Wiseman P.W., Hanrahan J.W., Investigating membrane protein dynamics in living cells. Biochem Cell Biol., Dec;84(6):825-31 (2006).

60. Benlimame, N., Q. He, S. Jie, D. Xiao, Y.J. Xu, M. Loignon, D.D. Schlaepfer, Alaoui-Jamali., M.A. FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion. J. Cell Biol., 171(3):505-516 (2005).

61. Brown, C.M., “Fluorescence Microscopy: Avoiding the Pitfalls”, J. Cell Sci., 120, 1703-1705. *Includes fold out poster with images taken at the facility (2007).

62. Caceres L, Nilson LA. Production of gurken in the nurse cells is sufficient for axis determination in the Drosophila oocyte. Development. May;132(10):2345-53. Epub 2005 Apr 13 (2005).

63. Chan,R Hardy, W. R., Dankort, D., Laing, M., and Muller, W. J. Modulation of Erbb2 signaling during development; a threshold level of erbb2 is required for development. Development 131,551-5560 (2004).

64. Cho, P., Gamberi C., Cho-Park, Y.A., Cho-Park, I.B., Lasko, P., Sonnenberg, N., Cap-dependent translational inhibition establishes two opposing morphogen gradients in Drosophila embryos. Curr Biol., 16:2035-41 (2006).

65. Fortier, A., de Chastellier, C., Balor, S., Gros., P., Birc1e/Naip5 rapidly antagonizes modulation of phagosome maturation by Legionella pneumophila. Cell Microbiol., 9:910-923 (2006).

66. Fournès, B., Farrah, J., Olson, M., Lamarche-Vane, N., and Beauchemin, N. Distinct Rho GTPase activities regulate epithelial intercellular targeting of the cell adhesion molecule CEACAM1: Involvement of the CEACAM1 transmembrane domain. Mol. Cell Biol. 20, 7291-7304 (2003).

67. Gingras, H., M. Krasilnikova, G. Bérubé, and Alain Nepveu. Biochemical Characterization of the Mammalian Cux 2 Protein. Gene 344: 273-285 (2005).

68. Goulet, B., Baruch, A., Moon, N. S., Poirier, M., Sansregret, L. L., Erickson, A., Bogyo, M. and Nepveu, A. Cathepsin L Isoform that Is Devoid of a Signal Peptide Localizes to the Nucleus in S Phase and Processes the CDP/Cux Transcription Factor. Mol Cell 14, 207-219 (2004).

69. Grote, D., Souabni, A, Busslinger, M. and Bouchard, M. Pax2/8-regulated Gata3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney. Development, 133:53-61 (2005).

70. Han, W., S. Nattel, T. Noguchi, andA. Shrier. C-terminal domain of Kv4.2 and associated KChIP2 interactions regulate functional expression and gating of Kv4.2. J Biol Chem 281(37):27134-27144 (2006).

71. Imaizumi, K. and Pollack, G.S. Central projections of auditory receptor neurons of crickets. Journal of Comparative Neurology 493:439-447 (2005).

72. Johnstone, O., Deuring, R., Bock, R., Linder, P., Fuller, M.T., Lasko, P. Belle is a Drosophila DEAD-box protein required for viability and in the germ line. Dev Biol. Jan 1;277(1):92-101, (2005).

73. Johnstone, O., Lasko, P., Interaction with eIF5B is essential for Vasa function during development. Development. Sep;131(17):4167-78. Epub 2004 Jul 27 (2004).

74. Khoury, H., Naujokas, M.A., Zuo, D., Sangwan, V., Frigault, M.M, Petkiewicz, S., Dankort, D.L., Muller, W.J., Park, M. HGF converts ErbB2/Neu epithelial morphogenesis to cell invasion. Molecular Biology Cell 16(2): 550-61 (2005).

75. Kim, H., Chan R., Dankort, D.L., Zou, D, Naujokas, M., Park, M. and Muller, W.J. The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2”:implications for erbB-2 mediated transformation and signalling. Oncogene. 24:7599-607 (2005).

76. Laplante, C., Nilson, L.A., Differential expression of the adhesion molecule Echinoid drives epithelial morphogenesis in Drosophila. Development. Aug;133(16):3255-64 (2006). Epub 2006 Jul 19. **Including Cover of Journal Issue.**

77. Liu, N., Dansereau, D.A., Lasko, P., Fat facets interacts with vasa in the Drosophila pole plasm and protects it from degradation. Curr Biol. Oct 28;13(21):1905-9, (2003).

78. Long J, Zuo D, Park M., Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin., J Biol Chem. Oct 21;280(42):35477-89. (2005) Epub 2005 Aug 1.

79. Marsat, G., and Pollack, G.S., Differential temporal coding of rhythmically diverse acoustic signals by a single interneuron. Journal of Neurophysiology 92: 939-948 (2004).

80. Rodrigues SP, Fathers KE, Chan G, Zuo D, Halwani F, Meterissian S, Park M., CrkI and CrkII function as key signaling integrators for migration and invasion of cancer cells., Mol Cancer Res. Apr;3(4):183-94 (2005).

81. Sheftel, A. D., An-Sheng, Z., Brown, C.M., Orian, S. S., Ponka, P. "Direct interorganellar transfer of iron from endosome to mitochondrion", Blood, In Press. (2007).

82. Silvius, J.R., Bhagatji, P., Leventis, R., Terrone., D., K-ras4B and prenylated proteins lacking "second signals" associate dynamically with cellular membranes. Mol Biol Cell, 17(1):192-202 (2006).

83. Szabo, E.Z., Numata, M., Lukashova, V., Lannuzzi, P., Orlowski, J., beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform. Proc Natl Acad Sci U S A. Feb 22;102(8):2790-5. Epub 2005 Feb 7 (2005).

84. Thomson, T., Lasko, P., Drosophila tudor is essential for polar granule assembly and pole cell specification, but not for posterior patterning. Genesis. Nov;40(3):164-70, (2004).

85. Torban E, Wang HJ, Patenaude AM, Riccomagno M, Daniels E, Epstein D, Gros P. Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation. Gene Expr Patterns. 7(3):346-354, (2007).

86. Tunstall, D.N. and Pollack, G.S. Temporal and directional processing by an identified interneuron, ON1, compared in cricket species that sing with different tempos. Journal of Comparative Physiology A, 191:363-372 (2005).

87. Wang, T.Y., R. Leventis, andJ.R. Silvius. Artificially lipid-anchored proteins can elicit clustering-induced intracellular signaling events in Jurkat T-lymphocytes independent of lipid raft association. J Biol Chem, 280(24):22839-22846 (2005).

88. White, D., Kurpios, N.A., Zuo, Dongmei, Hassell, J.A., Blaess, S., Mueller, U., Muller, W.J. Targeted disruption of B1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. Cancer Cell., 6: 159-170 (2004).