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On the function of Stomatin-like protein 2

Project Information

This collaboration involves three different laboratories: one at McGill, the other at the University of Cologne, and the third at the University of Geneva.  The aim is to establish the function of a novel protein named stomatin-like protein 2, using a coordinated strategy of cutting edge molecular and cellular techniques as well as animal models of disease. 

Project Date: 
01/01/2011 to 09/29/2022
Type of Project: 
Research Area: 
Health Research
Sub-Research Area: 
Health research
Funding Source: 
McGill University Project Leader Information
Project Leader: 

Joaquin Madrenas

Profile Picture: 
Primary Position
Faculty of Medicine
Microbiology & Immunology
Other Position/Appointment: 
Chairman of the Department of Microbiology and Immunology at McGill University. Canada Research Chair in Human Immunology
Research Interests: 
Dr. Madrenas has made seminal contributions to Science as illustrated by his publications in top journals (Science, Nature Medicine, Immunity, Journal of Experimental Medicine, The Lancet, and the Proceedings of the National Academy of Science USA). Among his discoveries are the different patterns of signalling through the T cell antigen receptor, the mechanisms of signalling by CTLA-4, and the signals delivered to T cells by bacterial superantigens. For his research, he has received numerous awards including a Canada Foundation for Innovation Researcher Award, a Premier’s Research Excellence Award, a Canada Research Chair, an Ontario Distinguished Researcher Award, a Canadian Who’s Who, The John B. Dossetor Mission Award in Research from The Kidney Foundation of Canada, the UWO Dean’s Award of Excellence in Research and UWO Faculty Scholar Award. In 2011, Dr. Madrenas was inducted to the Canadian Academy of Health Sciences.

Dr. Joaquín (Quim) Madrenas is Full Professor and Chairman of the Department of Microbiology and Immunology at McGill University.  Previously, he was professor of Microbiology and Immunology, and Medicine and Tier I Canada Research Chair in Immunobiology at The University of Western Ontario (UWO), and Head of Immunology at Robarts Research Institute.

Dr. Madrenas received an M.D. degree at the University of Barcelona, specialized in Nephrology and Transplantation at the University Autonoma of Barcelona, and obtained a Ph.D. degree in Immunology under Dr. Phillip Halloran, at the University of Alberta.  He was a visiting associate with Dr. Ronald Germain at the National Institutes of Health (Bethesda, MD, USA), before coming back to Canada. He was the founding Director of the FOCIS Centre for Clinical Immunology and Immunotherapeutics in London, ON, the first FOCIS Centre of Excellence in Canada.

Principal Investigator
Non-McGill Partners
Thomas Langer
Jean-Claude Martinou