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Selected Publications

Last Updated: 27/11/14

  1. A Leong, W Rehman, Z Dastani, CM Greenwood, N Timpson, L Langsetmo, C Berger, METASTROKE, L Fu, BYL Wong, S Malik, R Malik, DEC Cole D Goltzman, JB Richards. The causal effect of Vitamin D binding protein (DBP) levels on calcemic and cardiometablic diseases: A Mendelian randomization study. PLOS Medicine. Oct 29, 2014. doi:10.1371/journal.pmed.1001751 . This paper received an Editorial from PLOS Medicine.

  2. R Lui, A Montpetit, M Rousseau, SYM Wu, CMT Greenwood, TD Spector, M Pollak, C Polychronakos, JB Richards. Somatic Point Mutations Occurring in Early Development: A Monozygotic Twin Study. Journal of Medical Genetics.  2014 Jan;51(1):28-34 PMID: 24123875. This article has been recommended by The Faculty of 1000.

  3. J. Brent Richards, Hou-Feng Zheng & Tim D. Spector. (2012) Genetics of osteoporosis from genome-wide association studies: advances and challenges.  Nature Reviews Genetics 13576-588. doi:10.1038/nrg3228

  4. Hou-Feng Zheng*, Jon H. Tobias*, Emma Duncan*, David M. Evans*, Joel Eriksson, Lavinia Paternoster, Laura M. Yerges-Armstrong, Terho Lehtima, Ulrica Bergstrom,Mika Kahonen, Paul J. Leo, Olli Raitakari, Marika Laaksonen, Geoffrey C. Nicholson,Jorma Viikari, Martin Ladouceur, Leo-Pekka Lyytikainen, Carolina Medina-Gomez,Fernando Rivadeneira, Richard L. Prince, Harri Sievanen, William D. Leslie, Dan Mellstrom,John A. Eisman, Sofia Moverare-Skrtic, David Goltzman, David A. Hanley, Graeme Jones,Beate St. Pourcain, Yongjun Xiao, Nicholas J. Timpson, George Davey Smith, Ian R. Reid,Susan M. Ring, Philip N. Sambrook, Magnus Karlsson, Elaine M. Dennison, John P. Kemp, Patrick Danoy, Adrian Sayers, Scott G. Wilson, Maria Nethander, Eugene McCloskey, Liesbeth Vandenput, Richard Eastell, Jeff Liu, Tim Spector, Braxton D. Mitchell,Elizabeth A. Streeten, Robert Brommage, Ulrika Pettersson-Kymmer, Matthew A. Brown, Claes Ohlsson*, J. Brent Richards*, Mattias Lorentzon*. (2012) WNT16 Influences Bone Mineral Density, Cortical Bone Thickness, Bone Strength, and Osteoporotic Fracture Risk. PLoS Genetics 8(7): e1002745. doi:10.1371/journal.pgen.1002745

  5. Z Dastani,* M-F Hivert,* N Timpson,* JRB Perry,* X Yuan,* RA Scott,* P Henneman,* I M. Heid,* JR Kizer,* L-P Lyytikainen,* C Fuchsberger,* T Tanaka, A P Morris, K Small, A Isaacs, M Beekman, S Coassin, K Lohman, L Qi, S Kanoni, J S Pankow, H-W Uh, Y Wu, A Bidulescu, L J Rasmussen-Torvik, CMT Greenwood, M Ladouceur, J Grimsby, AK Manning, C-T Liu, J Kooner, VE Mooser, P Vollenweider,  KA Kapur, J Chambers, NJ Wareham, C Langenberg, R Frants, K Willems-vanDijk, BA Oostra, S M Willems, C Lamina, Thomas Winkler, BM Psaty, RP Tracy, J Brody, I Chen, J Viikari, M Kähönen, PP Pramstaller,  M Evans, B St Pourcain, N Sattar, A Wood, S Bandinelli, Olga D. Carlson, JM Egan, S Böhringer, D van Heemst, L Kedenko, K Kristiansson, M-L Nuotio, B-M Loo, T Harris, M Garcia, A Kanaya, M Haun, N Klopp, HE Wichmann, P Deloukas, E Katsareli, DJ Couper, BB Duncan, M Kloppenburg, LS Adair, JB Borja, DIAGRAM+ Consortium, MAGIC Consortium, GLGC Investigators, MuTHER Consortium, JG Wilson, S Musani, X Guo, T Johnson, R Semple, TM Teslovich, MA Allison, S Redline, SG Buxbaum, KL Mohlke, I Meulenbelt, CM Ballantyne, GV Dedoussis, FB Hu, Y Liu, B Paulweber, TD Spector, PE Slagboom, L Ferrucci, A Jula, M Perola, O Raitakari, JC Florez, V Salomaa,** JG Eriksson, TM Frayling,** AA Hicks,** T Lehtimäki,** GD Smith,**, DS Siscovick,** F Kronenberg,** C van Duijn,** RJF Loos,** DM Waterworth,** JB Meigs,** J Dupuis,** JB Richards**. Novel Loci for Adiponectin Levels and their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals. PLoS Genetics, 2012 Mar 8(3): e1002607.doi:10.1371/journal.pgen.1002607.
  6. M Ladouceur  , Z Dastani , YS Aulchenko, CMT Greenwood, JB Richards. The Empirical Power of Rare Variant Association Methods: Results from Sanger Sequencing in 1,998 Individuals.PLoS Genetics.  2012 Feb 8(2):e1002496.doi:10.1371/journal.pgen.1002496.

  7.  TJ Wang*, F Zhang*, JB Richards*, B Kestenbaum*, JB van Meurs*, D Berry*, et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study.The Lancet. 2010 Jul 17;376(9736):180-8. Epub 2010 Jun 10.

  8. JB Richards, D Waterworth, S O’Rahilly, MF Hivert, RJF Loos, et al. A genome-wide association study reveals variants in ARL that influence adiponectin levels.PLoS Genetics. 2009 Dec;5(12):e1000768. Epub.

  9. JB Richards, FK Kavvoura, F Rivadeneira, U Styrkársdóttir, K Estrada, et al. A Systematic Evaluation of 150 Candidate Genes for their Association with Osteoporosis and Osteoporotic Fracture in a Meta-Analysis of Genome-Wide Association Data.Annals of Internal Medicine. 2009 Oct 20;151(8):528-37.

  10. JB Richards, X Yuan, F Geller, D Waterworth, V Bataille, et al. Genome-Wide Association Study Reveals a Novel Locus for Male Pattern Baldness.Nature Genetics. Nov 2008;40(11):1281-4.

  11. JB Richards,* F Rivadeneira,* M Inouye,* TM Pastinen, N Soranzo,et al. Genome-Wide Association Study for Bone Mineral Density Reveals Genetic Variants Associated with Osteoporosis and Osteoporotic Fractures.The Lancet. 2008 May 3;371(9623):1505-12.

  12. F Rivadeneira,* U Styrkársdóttir,* K Estrada,* B Halldórsson,* YH Hsu,* JB Richards,* MC Zillikens,* et al. Twenty bone mineral density loci identified by large-scale meta-analysis of genome-wide association studies.Nature Genetics. 2009 Nov;41(11):1199-206. Epub 2009 Oct 4.

  13. JB Richards, A Papaioannou, JD Adachi, L Joseph, HE Whitson, et al. Effect of selective serotonin reuptake inhibitors on the risk of fracture.Archives of Internal Medicine. 2007 Jan 22;167(2):188-94.

  14. JB Richards, WD Leslie, L Joseph, K Siminoski, DA Hanley, et al. Changes to Osteoporosis Prevalence According to Method of Risk Assessment.Journal of Bone Mineral Research. February 2007:22:228-34.

  15. M Mangino, JB Richards, N Soranzo, G Zhai, A Aviv, et al. A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length.Journal of Medical Genetics. 2009 Jul;46(7):451-4. Epub 2009 Apr 8.