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Zari Dastani

Academic Training

Ph.D (Genetics), 2009, McGill University, (Montréal, Québec)

M.D., 1997, Mashhad University, (Mashhad, Iran)

Publications

  1. Iatan I, Dastani Z, Do R, Weissglas-Volkov D, Ruel I, Lee JC, Huertas-Vazquez A, Taskinen MR, Prat A, Seidah NG, Pajukanta P, Engert JC, Genest J.Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levels. Circ Cardiovasc Genet. 2009 Oct;2(5):467-75. Epub 2009 Aug 22.
  2. Dastani Z, Pajukanta P, Marcil M, Rudzicz N, Ruel I, Bailey SD, Lee JC, Lemire M, Faith J, Platko J, Rioux J, Hudson TJ, Gaudet D, Engert JC, Genest J.Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. Eur J Hum Genet. 2010 Mar;18(3):342-7. Epub 2009 Oct 21.
  3. Lee JC, Weissglas-Volkov D, Kyttälä M, Dastani Z, Cantor RM, Sobel EM, Plaisier CL, Engert JC, van Greevenbroek MM, Kane JP, Malloy MJ, Pullinger CR, Huertas-Vazquez A, Aguilar-Salinas CA, Tusie-Luna T, de Bruin TW, Aouizerat BE, van der Kallen CC, Croce CM, Aqeilan RI, Marcil M, Viikari JS, Lehtimäki T, Raitakari OT, Kuusisto J, Laakso M, Taskinen MR, Genest J, Pajukanta P.WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels. Am J Hum Genet. 2008 Aug;83(2):180-92.
  4. Dastani Z, Ruel IL, Engert JC, Genest J Jr, Marcil M. Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol.BMC Med Genet. 2007 Dec 18;8:79.
  5. Dastani Z, Engert JC, Genest J, Marcil M.Genetics of high-density lipoproteins. Curr Opin Cardiol. 2006 Jul;21(4):329-35. Review.
  6. Marcil M, Vu H, Cui W, Dastani Z, Engert JC, Gaudet D, Castro-Cabezas M, Sniderman AD, Genest J Jr, Cianflone K.Identification of a novel C5L2 variant (S323I) in a French Canadian family with familial combined hyperlipemia. Arterioscler Thromb Vasc Biol. 2006 Jul;26(7):1619-25. Epub 2006 Apr 20.
  7. Dastani Z, Quiogue L, Plaisier C, Engert JC, Marcil M, Genest J, Pajukanta P.Evidence for a gene influencing high-density lipoprotein cholesterol on chromosome 4q31.21. Arterioscler Thromb Vasc Biol. 2006 Feb;26(2):392-7. Epub 2005 Dec 1.
  8. Dastani Z, Dangoisse C, Boucher B, Desbiens K, Krimbou L, Dufour R, Hegele RA, Pajukanta P, Engert JC, Genest J, Marcil M. A novel nonsense apolipoprotein A-I mutation (apoA-I(E136X)) causes low HDL cholesterol in French Canadians. Atherosclerosis. 2006 Mar;185(1):127-36. Epub 2005 Jul 14.