Faleh Tamimi

Faleh [dot] tamimimarino [at] mcgill [dot] ca (Email)
Tel:(514) 398-7203 ext. 09654

Dr. Tamimi is a dentist who holds 2 clinical certificates, in Geriatric Dentistry, and in Implant-Prosthodontics, respectively, as well as a Ph.D. in Biomaterials. He is Also a Canada Research Chair in Translational Craniofacial Research.

Before being appointed as Assistant Professor in the Faculty of Dentistry, Dr. Tamimi held a postdoctoral position at McGill University for two years. During his training, Dr. Tamimi worked in the Departments of Oral Surgery, Prosthodontics, Physical Chemistry (University Complutense of Madrid, Spain) and Pharmaceutical Technology (University of Parma, Italy), developing a multidisciplinary research profile and network.

Dr. Tamimi’s research interests are in finding solutions to relevant clinical problems through the development and application of new biomaterials and pharmacological treatments. Many dental patients suffer from severe bone resorption due to tooth loss, infection and trauma, limiting their treatment options. Dr. Tamimi’s research in dental surgery involves the development of treatment-specific biomaterials and drugs for dental bone augmentation, as well as new surgical techniques for this purpose. This research line includes the synthesis of new polymeric and ceramic biomaterials, the formulation drug delivery systems for controlled release of bioactive molecules into treatment sites, and the use of pharmacological treatments for tissue regeneration. In addition, Dr. Tamimi is conducting several clinical trials evaluating the performance of new biomaterials and surgical techniques in dental patients.

His work has attracted much interest from the scientific community and from the popular media. His recent publications have been highlighted in Nature Reviews Endocrinology, as well as in the public media (i.e. print, radio and television interviews in media such as Newsweek Magazine,The Wall Street Journal, Radio Canada, CTV, Global News). Moreover, his discoveries on the cholinergic regulation of bone have been highlighted by CIHR  as one of the most relevant and important research programs on bone in Canada.

Click here to watch on YouTube. 

 


PUBLICATIONS

JOURNAL PAPERS

Eimar H, Tamimi F, Retrouvey JM, Rauch F, Aubin J, McKee MD. Craniofacial and Dental Defects in the Col1a1Jrt/+ Mouse Model of OI. Journal of dental Research 2016 (Accepted in press).

Wu X, Al-Abedalla K, Eimar H, Arekunnath Madathil S, Abi-Nader S, Daniel NG, Nicolau B, Tamimi F. Antihypertensive Medications and the Survival Rate of Osseointegrated Dental Implants A Cohort Study. Clinical Implant Dentistry and Related Research ( Accepted in press).

Al Subaie A, Emami E, Tamimi I, Laurenti M, Eimar H, Abdallah MN, Tamimi F. Systemic Administration of Omeprazole Interferes with Bone Healing & Implant Osseointegration: An in vivo study on rat tibiae. J Clin Periodontol. 2016 Jan 4. doi: 10.1111/jcpe.12506.

Ghanem H, Ian Afrashtehfar K, Abi-Nader S, Tamimi F. Impact of a "TED-Style" resentation on potential patients' willingness to accept dental implant therapy: a one-group, pre-test posttest study. J Adv Prosthodont. 2015 Dec;7(6):437-445.

Eimar H, Alebrahim S, Manickam G, Al-Subaie A, Abu-Nada L, Murshed M, Tamimi F. Donepezil regulates energy metabolism and favors bone mass accrual. Bone. 2015;84:131-138.

Sheikh Z, Zhang YL, Grover L, Merle GE, Tamimi F, Barralet J. In vitro degradation and in vivo resorption of dicalcium phosphate cement based grafts. Acta Biomater. 2015 Oct 15;26:338-46. doi: 10.1016/j.actbio.2015.08.031. Epub 2015 Aug 20.

AF Tamimi, I Tamimi, Abdelaziz, Q Saleh, F Obeidat, M Al-Husseini, W Haddadin, M, F Tamimi. Epidemiology of Malignant and Non-Malignant Brain Tumors in Jordan. Journal of Neuroepidemiology, 2015;45(2):100-8.

Momani M, Abdallah MN, Al-Sebaie D, Tamimi F. Rehabilitation of a Completely Edentulous Patient with Nonreducible Bilateral Anterior Dislocation of the Temporomandibular Joint: A Prosthodontic Challenge-Clinical Report. J Prosthodont. 2015 Jul 27. doi: 10.1111/jopr.12318. [Epub ahead of print]

Al-Abedalla K, Torres J, Cortes AR, Wu X, Nader SA, Daniel N, Tamimi F. Bone Augmented With Allograft Onlays for Implant Placement Could Be Comparable With Native Bone. J Oral Maxillofac Surg. 2015 Nov;73(11):2108-22.

Tamimi I, Montesa G, Collado F, González D, Carnero P, Rojas F, Nagib M, Pérez V, Álvarez M, Tamimi F. Displaced proximal humeral fractures: When is surgery necessary? Injury. 2015;46(10):1921-9.

Al Subaie AE, Eimar H, Abdallah MN, Durand R, Feine J, Tamimi F, Emami E. Anti-VEGFs hinder bone healing and implant osseointegration in rat tibiae. J Clin Periodontol. 2015;42(7):688-96.

Torres J, Tamimi I, Cabrejos-Azama J, Tresguerres I, Alkhraisat M, López-Cabarcos E, Hernández G, Tamimi F. Monetite granules versus particulate autologous bone in bone regeneration. Ann Anat. 2015 Jul;200:126-33.

Cortes AR, Eimar H, Barbosa Jde S, Costa C, Arita ES, Tamimi F. Sensitivity and specificity of radiographic methods for predicting insertion torque of dental implants. J Periodontol. 2015;86(5):646-55.

Alageel O, Abdallah MN, Luo ZY, Del-Rio-Highsmith J, Cerruti M, Tamimi F. Bonding metals to poly(methyl methacrylate) using aryldiazonium salts. Dent Mater. 2014 Dec 2. pii: S0109-5641(14)00654-X. doi: 10.1016/j.dental.2014.11.002.

Garcia-Denche JT, Abbushi A, Hernández G, Fernández-Tresguerres I, Lopez-Cabarcos E, Tamimi F. Nasal Floor Elevation for Implant Treatment in the Atrophic Premaxilla: A Within-Patient Comparative Study. Clin Implant Dent Relat Res. 2015;17 Suppl 2:e520-30.

Xixi Wu, K Abdallah, B Nicolau, S Abi-Nader, N Daniel, F Tamimi. SSRIs and the Risk of Osseointegrated Implant Failure --A cohort study. J Dent Res. 2014 Sep 3. pii: 0022034514549378. [Epub ahead of print] PubMed PMID: 25186831.

Arthur Rodriguez Gonzalez Cortes, Zhaoyu Jin, Matthew Daniel Morrison, Emiko Saito Arita, Jun Song, Faleh Tamimi. Mandibular tori are associated with mechanical stress and mandibular shape, Journal of Oral and Maxillofacial Surgery, 2014;72(11):2115-2125.

Tresguerres IF, Tamimi F, Eimar H, Barralet J, Torres J, Blanco L, Fernández-Tresguerres JA. Resveratrol as anti-aging therapy for age-related bone loss. Rejuvenation Res. 2014 Jun 23. [Epub ahead of print] PubMed PMID: 24956408.

Ghadimi E, Eimar H, Song J, Marelli B, Ciobanu O, Abdallah MN, Stähli C, Nazhat SN, Vali H, Tamimi F. Regulated fracture in tooth enamel: a nanotechnological strategy from nature. J Biomech. 2014; 47(10):2444-51.

Tamimi F, Torres J, Al-Abedalla K, Lopez-Cabarcos E, Alkhraisat MH, Bassett DC, Gbureck U, Barralet JE. Osseointegration of dental implants in 3D-printed synthetic onlay grafts customized according to bone metabolic activity in recipient site. Biomaterials. 2014; 35(21):5436-45. doi: 10.1016/j.biomaterials.2014.03.050. Epub 2014 Apr 13. PubMed PMID: 24726538.

Abdallah MN, Light N, Amin WM, Retrouvey JM, Cerruti M, Tamimi F. Development of a composite resin disclosing agent based on the understanding of tooth staining mechanisms. J Dent. 2014;42(6):697-708. doi:10.1016/j.jdent.2014.03.004. Epub 2014 Mar 14. PubMed PMID: 24632474.

Tresguerres IF, Tamimi F, Eimar H, Barralet J, Prieto S, Torres J, Calvo-Guirado JL, Fernández-Tresguerres JA. Melatonin dietary supplement as an anti-aging therapy for age-related bone loss. Rejuvenation Res. 2014 Mar 11.[Epub ahead of print] PubMed PMID: 24617902.

Abi Nader S, Eimar H, Momani M, Shang K, Daniel NG, Tamimi F. Plaque Accumulation Beneath Maxillary All-on-4™ Implant-Supported Prostheses. Clin Implant Dent Relat Res. 2015;17(5):932-7.

Eimar H, Perez Lara A, Tamimi I, Márquez Sánchez P, Gormaz Talavera I, Rojas Tomba F, García de la Oliva T, Tamimi F. Acetylcholinesterase inhibitors and healing of hip fracture in Alzheimer's disease patients: a retrospective cohort study. J Musculoskelet Neuronal Interact. 2013;13(4):454-63.

Ghadimi E, Eimar H, Marelli B, Nazhat SN, Asgharian M, Vali H, Tamimi F. Trace elements can influence the physical properties of tooth enamel. Springerplus. 2013;2:499.

Jesus Torres, Xixi Wu, PP Martinez, Hazem Eimar, E Lopez-Cabarcos, Tamimi F. Membranes Over the Lateral Window in Sinus Augmentation Procedures. A Two Arm and Split Mouth Randomized Clinical Trials, J Clin Periodontol. 2013 Nov;40(11):1043-51.

Arthur Cortes, Pinheiro LR, Cavalcanti MGP, Arita ES, Tamimi F. Sinus Floor Bone Failures in Maxillary Sinus Floor Augmentation: A Case-Control Study. Clin Implant Dent Relat Res. 2015;17:335-42.

Eimar H, Tamimi I, Murshed M, Tamimi F. Cholinergic regulation of bone. J Musculoskelet Neuronal Interact. 2013;13(2):124-32

Tamimi F, Comeau P, Le Nihouannen D, Zhang YL, Bassett DC, Khalili S, Gbureck U, Tran SD, Komarova S, Barralet JE. Perfluorodecalin and bone regeneration. Eur Cell Mater. 2013;25:22-36.

Z. Khavandgar, S. Alebrahim, H. Eimar, F. Tamimi, M.D. McKee, M. Murshed. Local Regulation of Tooth Mineralization by Sphingomyelin Phosphodiesterase 3. J Dent Res. 2013;92(4):358-64.

Matthew Morrison, Faleh Tamimi. Oral tori are associated with local mechanical and systemic factors: A case-control study Journal of Oral and Maxillofacial Surgery. J Oral Maxillofac Surg. 2013;71(1):14-22.

Tamimi Mariño I, Sesma Solis P, Pérez Lara A, Martinez Malo J, Vazquez ML, Tamimi F. Sensitivity and positive predictive value of magnetic resonance imaging in the diagnosis of elastofibroma dorsi: review of fourteen cases J Shoulder Elbow Surg. 2013;22(1):57-63.

Eimar H, Siciliano R, Abdallah MN, Nader SA, Amin WM, Martinez PP, Celemin A, Cerruti M, Tamimi F. Hydrogen peroxide whitens teeth by oxidizing the organic structure. J Dent. 2012;40 Suppl 2:e25-33.

Eimar H, Ghadimi E, Marelli B, Vali H, Nazhat SN, Amin WM, Torres J, Ciobanu O, Albuquerque Junior RF, Tamimi F. Regulation of enamel hardness by its crystallographic dimensions. Acta Biomater. 2012;8(9):3400-10. Epub 2012 Jun 8. PubMed PMID: 22684114.

Tamimi F, Nihouannen DL, Eimar H, Sheikh Z, Komarova S, Barralet J. The effect of autoclaving on the physical and biological properties of dicalcium phosphate dihydrate bioceramics: Brushite vs. monetite. Acta Biomater. 2012 Aug;8(8):3161-9. Epub 2012 Apr 20. PubMed PMID: 22522010.

Tamimi I, Ojea T, Sanchez-Siles JM, Rojas F, Martin I, Gormaz I, Perez A, Dawid-Milner MS, Mendez L, Tamimi F. Acetylcholinesterase inhibitors and the risk of hip fracture in Alzheimer's disease patients: A case-control study. J Bone Miner Res. 2012 Jul;27(7):1518-27. doi: 10.1002/jbmr.1616. PubMed PMID: 22467182.

Tresguerres IF, Clemente C, Blanco L, Khraisat A, Tamimi F, Tresguerres JA. Effects of local melatonin application on implant osseointegration. Clin Implant. Dent Relat Res. 2012 Jun;14(3):395-9. doi: 10.1111/j.1708-8208.2010.00271.x. Epub 2010 Apr 23. PubMed PMID: 20455901.

Tamimi F, Sheikh Z, Barralet J. Dicalcium phosphate cements: brushite and monetite. Acta Biomater. 2012;8(2):474-87.

Torres J, Tamimi F, Alkhraisat MH, Prados-Frutos JC, Rastikerdar E, Gbureck U, Barralet JE, López-Cabarcos E. Vertical bone augmentation with 3D-synthetic monetite blocks in the rabbit calvaria. J Clin Periodontol. 2011;38(12):1147-53.

Eimar H, Marelli B, Nazhat SN, Abi Nader S, Amin WM, Torres J, de Albuquerque RF Jr, Tamimi F. The role of enamel crystallography on tooth shade. J Dent. 2011;39 Suppl 3:e3-10.

Gustavo Duque, Dao Chao Huang, Natalie Dion, Michael Macoritto, Daniel Rivas, Wei Li, Xian Fang Yang, Jiarong Li, Jing Liang, Faleh Tamim Marino, Jake Barralet, Viorica Lascau, Claire Deschênes, Louis‐Georges Ste‐Marie, Richard Kremer. Interferon γ plays a role in bone formation in vivo and rescues osteoporosis in ovariectomized mice. J Bone Miner Res. 2011;26(7):1472-83.

Faleh Tamimi, Damien Le Nihouannen, David C Bassett, Suzette Ibasco, Uwe Gbureck, Jonathan Knowles, Adrian Wright, Andrew Flynn, Svetlana V Komarova, Jake E Barralet. Biocompatibility of magnesium phosphate minerals and their stability under physiological Conditions. Acta Biomater. 2011;7(6):2678-85. Epub 2011 Feb 13.

Gomez-Polo M, Bartens F, Sala L, Tamini F, Celemin A, Del Rio J. The correlation between crown-implant ratios and marginal bone resorption: a preliminary clinical study. Int J Prosthodont. 2010;23(1):33-7.

Karmouty-Quintana H, Tamimi F, McGovern TK, Grover LM, Martin JG, Barralet JE. Sustained steroid release in pulmonary inflammation model. Biomaterials. 2010;31(23):6050-9.

Tamimi F, Torres J, Bassett D, Barralet J, Cabarcos EL. Resorption of monetite granules in alveolar bone defects in human patients. Biomaterials. 2010;31(10):2762-9.

De la Riva B, Sánchez E, Hernández A, Reyes R, Tamimi F, López-Cabarcos E, Delgado A, Evora C. Local controlled release of VEGF and PDGF from a combined brushite-chitosan system enhances bone regeneration. J Control Release. 2010;143(1):45-52.

Alkhraisat MH, Rueda C, Cabrejos-Azama J, Lucas-Aparicio J, Mariño FT, Torres García-Denche J, Jerez LB, Gbureck U, Cabarcos EL.Loading and release of doxycycline hyclate from strontium-substituted calcium phosphate cement. Acta Biomater. 2010;6(4):1522-8.

Tamimi AF, Tamimi F. Medical education in Jordan. Med Teach. 2010;32(1):36-40.

Jesús Torres,  Faleh Tamimi,  Isabel F. Tresguerres, Mohammad H. Alkhraisat, Ameen Khraisat, Luis Blanco, Enrique López-Cabarcos.  Effect of Combining PRP with Anorganic Bovine Bone on Vertical Bone Regeneration: Early Healing Assessment on Rabbit Calvariae. International Journal of Oral and Maxillofacial Implants, 2010;25(1):123-9.

Torres J, Tamimi F, Alkhraisat MH, Manchón A, Linares R, Prados-Frutos JC, Hernández G, López Cabarcos E. Platelet-rich plasma may prevent titanium-mesh exposure in alveolar ridge augmentation with anorganic bovine bone. J Clin Periodontol. 2010 Oct;37(10):943-51.

Tamimi F, Torres J, Gbureck U, Lopez-Cabarcos E, Bassett DC, Alkhraisat MH, Barralet JE. Craniofacial vertical bone augmentation: A comparison between 3D printed monolithic monetite blocks and autologous onlay grafts in the rabbit.  Biomaterials. 2009;30(31):6318-26.

Mohammad Hamdan Alkhraisat, Carmen Rueda, Luis Blanco Jerez, Faleh Tamimi Mariño, Jesus Torres, Uwe Gbureck, Enrique Lopez Cabarcos. Effect of silica gel on the cohesion, properties and biological performance of brushite cement. Acta Biomaterialia, 2009;5(8):3150-6.

Jesús Torres,  Faleh Tamimi,  Isabel F. Tresguerres, Mohammad H. Alkhraisat, Ameen Khraisat, Luis Blanco, Enrique López-Cabarcos.  Effect of platelet-rich plasma on sinus lifting: a randomized-controlled clinical trial. Journal of Clinical Periodontology J Clin Periodontol. 2009;36(8):677-87.

Mohammad Hamdan Alkhraisat, Uwe Gbureck, Luis Blanco, Faleh Tamimi, Carmen Rueda, Jesus Torres Enrique Lopez Cabarcos. Effect of hyaluronic acid on brushite cement cohesion Acta Biomaterialia, 2009;5(8):3150-6.

Suzette Ibasco, Faleh Tamimi, Robert Meszaros, Damien Le Nihouannen, Srikar Vengallatore, Edward Harvey, Jake E Barralet. Magnesium sputtered titanium for the formation of bioactive coatings Acta Biomaterialia 2009;5(6):2338-47.

M. Sánchez-Paniagua López, F. Tamimi, E. López-Cabarcos, B. López-Ruiz Highly sensitive amperometric biosensor base on a biocompatible calcium phosphate cement. Biosensors and Bioelectronics, 2009;24(8):2574-9.

Jesús Torres, Faleh Tamimi, Ignacio García, Herrero A, Rivera B, Sobrino JA, Hernandez G. Dental implants in a patient with Paget's disease under bisphosphonate treatment: a case report. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2009; 107(3):387-92.

Faleh Tamimi, Jesus Torres, Enrique Lopez-Cabarcos, David C. Bassett, Pamela Habibovic, Elena Luceron, Jake E. Barralet. Minimally invasive maxillofacial vertical bone augmentation using brushite based cements. Biomaterials 2009;30(2):208-16.

Rossdeutscheur L, Huang DC, Yang  XF, Marino FT, Barralet J, Kremer R. Effect of 1,25-Dihydroxyvitamin D-3 and 25-Hydroxyvitamin D-3 on Osteoblastogenesis and Bone Strength in Vitamin D Sufficient Growing Mice. Journal of Bone and Mineral Research 2008;23:S291-S291.   

Huang DC, Duque G, Yang XF, Marino FT, Barralet J, Kremer R. Low Dose Administration of Interferon gamma Stimulates Osteoblastogenesis and Prevents Ovariectomy-Induced Osteoporosis in C57BL/6 Mice.  Journal of Bone and Mineral Research 2008;23 S457-S457  

Tamimi F, Torres J, Kathan C, Baca R, Clemente C, Blanco L, Cabarcos EL.Bone regeneration in rabbit calvaria with novel monetite granules. J Biomed Mater Res A. 2008;87(4):980-5.

Jesús Torres, Faleh Tamimi, Ignacio García, Jose Luis Cebrian, Enrique López-Cabarcos, Antonio Lopez. Management of atrophic maxilla in severe osteoporosis treated with bisphosphonates: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008;106(5):668-72.

Tamimi F, Kumarasami B, Doillon C, Gbureck U, Nihouannen DL, Cabarcos EL, Barralet JE.Brushite-collagen composites for bone regeneration.Acta Biomater. 2008;4(5):1315-21.

Tamimi F, Torres J, Bettini R, Ruggera F, Rueda C, López-Ponce M, Lopez-Cabarcos E. Doxycycline sustained release from brushite cements for the treatment of periodontal diseases.J Biomed Mater Res A. 2008;85(3):707-14.

Jesús Torres, Faleh M. Tamimi, Isabel F. Tresguerres, Mohammad H. Alkhraisat, Ameen Khraisat, Enrique Lopez-Cabarcos, Luis Blanco. Effect of Solely Applied Platelet-Rich Plasma on Osseous Regeneration Compared to Bio-Oss®: A Morphometric and Densitometric Study on Rabbit Calvaria. Clin Implant Dent Relat Res. 2008;10(2):106-12.

Alkhraisat MH, Mariño FT, Rodríguez CR, Jerez LB, Cabarcos EL. Combined effect of strontium and pyrophosphate on the properties of brushite cements. Acta Biomater. 2008;4(3):664-70.

Alkhraisat MH, Mariño FT, Retama JR, Jerez LB, López-Cabarcos E. Beta-tricalcium phosphate release from brushite cement surface. J Biomed Mater Res A. 2008;84(3):710-7.

Rubio-Retama J, Tamimi FM, Heinrich M, López-Cabarcos E. Synthesis and characterization of poly(magnesium acrylate) microgels. Langmuir. 2007;23(16):8538-43.'

Torres J, Tresguerres I, Tamimi F, Clemente C, Niembro E, Blanco L. Influence of platelet-rich plasma on bone regeneration: a histomorphometric study in rabbit calvaria. Int J Oral Maxillofac Implants. 2007;22(4):563-8.

Tamimi FM, Montalvo S, Tresguerres I, Blanco Jerez L. A comparative study of 2 methods for obtaining platelet-rich plasma. J Oral Maxillofac Surg. 2007;65(6):1084-93.

Rubio-Retama J, Mariño FT, López-Cabarcos E. Enzymatic biodegradable micro-reactors for therapeutic applications. J Biomed Mater Res B Appl Biomater. 2007;83(1):145-52. 

Tamimi-Mariño F, Mastio J, Rueda C, Blanco L, López-Cabarcos E.Increase of the final setting time of brushite cements by using chondroitin 4-sulfate and silica gel. J Mater Sci Mater Med. 2007;18(6):1195-201.

Mariño FT, Torres J, Tresguerres I, Jerez LB, Cabarcos EL. Vertical bone augmentation with granulated brushite cement set in glycolic acid. J Biomed Mater Res A. 2007;81(1):93-102.

Mariño FT, Torres J, Hamdan M, Rodríguez CR, Cabarcos EL.Advantages of using glycolic acid as a retardant in a brushite forming cement. J Biomed Mater Res B Appl Biomater. 2007;83(2):571-9.

Tamimi F, Torres J, Tresguerres I, Clemente C, López-Cabarcos E, Blanco LJ. Bone augmentation in rabbit calvariae: comparative study between Bio-Oss and a novel beta-TCP/DCPD granulate. J Clin Periodontol. 2006;33(12):922-8.